Results 121 to 130 of about 113,396 (305)

Interstitial 11q Deletions and Terminal 11q Duplications Cause a Bleeding Tendency due to Platelet Dysfunction That Is Similar to 11q Deletions Causing Jacobsen Syndrome

European Journal of Haematology, EarlyView.
ABSTRACT Introduction Jacobsen syndrome, resulting from a terminal deletion of chromosome 11 (11q), may lead to an increased bleeding tendency due to low platelet counts or platelet dysfunction. Currently, information on bleeding tendency and platelet function in patients with nonterminal 11q‐aberrations such as larger deletions, interstitial 11q ...
Elise J. Huisman, Virgil A. S. H. Dalm, Marieke Joosten, Frans J. Smiers, Leendert Porcelijn, Arjan Hoogendijk, Hans Janssen, Nicole N. van der van der Wel, Idske C. L. Kremer Hovinga, Masja de Haas, Marjon H. Cnossen   +10 more
wiley   +1 more source

Tumor‐Resident Microbiota‐Based Risk Model Predicts Neoadjuvant Therapy Response of Locally Advanced Esophageal Squamous Cell Carcinoma Patients

Advanced Science
Few predictive biomarkers exist for identifying patients who may benefit from neoadjuvant therapy (NAT). The intratumoral microbial composition is comprehensively profiled to predict the efficacy and prognosis of patients with esophageal squamous cell ...
Hong Wu, Qianshi Liu, Jingpei Li, Xuefeng Leng, Yazhou He, Yiqiang Liu, Xia Zhang, Yujie Ouyang, Yang Liu, Wenhua Liang, Chuan Xu   +10 more
doaj   +1 more source

Prevalence of peripheral dental caries and diastemata in horses fed high‐carbohydrate diets

Equine Veterinary Education, EarlyView.
Summary Background Peripheral dental caries and diastemata impair equine oral health. Diets rich in soluble carbohydrates are suspected risk factors, but few studies have assessed their impact. In Brazil, sugarcane is widely used as a forage source due to its availability and low cost.
S. L. Paredes, R. P. Mendes, M. D. Lacerenza, R. G. S. Dória, J. d. A. Arantes, L. S. B. Silva, R. R. Corrêa   +6 more
wiley   +1 more source

The competitive interplay of 12‐oxophytodienoic acid (OPDA), protein thiols, and glutathione

The FEBS Journal, EarlyView.
12‐Oxophytodienoic acid (OPDA) is a phytohormone involved in plant growth and stress defense. Due to its cyclopentenone moiety, OPDA can form Michael adducts with thiol‐containing compounds such as glutathione and cysteine residues of proteins, resulting in alterations of the cellular redox regulatory network.
Madita Knieper, Ruben Schwarz, Lara Vogelsang, Jens Sproß, Armağan Kaya, Maike Bittmann, Harald Gröger, Andrea Viehhauser, Karl‐Josef Dietz   +8 more
wiley   +1 more source

Identification of RMP24 and RMP64, human ribonuclease MRP-specific protein components

Cell Reports
Summary: Human RNase MRP is a ribonucleoprotein (RNP) enzyme that processes precursor rRNA (pre-rRNA) at ITS1 site 2 and may have additional activities. It is an endonuclease related to RNase P, which processes pre-tRNAs and pre-tRNA-like substrates.
Rui Che, Bhoomi Mirani, Monireh Panah, Xiaotong Chen, Hong Luo, Andrei Alexandrov   +5 more
doaj   +1 more source

The Proper Forcing Axiom and the Singular Cardinal Hypothesis

, 2005
We show that the Proper Forcing Axiom implies the Singular Cardinal Hypothesis.
Viale, Matteo
core   +1 more source

Cost reduction using process analysis in company PEGRES obuv s.r.o. [PDF]

, 2012
Firma PEGRES obuv s.r.o. se již delší dobu potýká se stagnací v oblasti plánování a řízení výroby. Některé podnikové procesy jsou nyní značně zastaralé a v aktuálních podmínkách již neefektivní.
Gřeš, Jan
core  

Risk Perceptions and Corporate Financing Behavior

Financial Management, EarlyView.
ABSTRACT Using a recently developed measure of financial market risk perceptions, we show that risk perceptions affect firm‐level corporate financing behavior. Firms tend to adjust their capital structures to cater to investors' appetite for risk. When perceived risks are low, firms tend to choose more leveraged capital structures to take advantage of ...
Youngmin Choi, Armen Hovakimian, Joonsung Won   +2 more
wiley   +1 more source

Theory of constraints (TOC) production and manufacturing performance [PDF]

, 2016
This paper is based on an empirical study of the relationship between Theory of Constraints (TOC) production and operational performance in manufacturing plants.
Panizzolo, Roberto
core  

Development of CCMb: A Low‐Mg Calcite Reference Material for In Situ Measurement of δ18O, δ13C and Selected Trace Elements

Geostandards and Geoanalytical Research, EarlyView.
Key Points Low‐Mg calcite RM developed for in situ microanalysis applications in palaeoclimatology (δ18O, δ13C; Mg, Sr m/m). New data for calcite CRM IAEA‐603 (δ18O, δ13C by SIMS and GS‐IRMS; Mg m/m). No detectable IMF effect of Mg on SIMS δ18O determinations for mass fractions < 3650 μg g‐1.
Andreas T. Hertwig, Maciej G. Śliwiński, Irene Cantarero, Richard A. Stern, Carles Fàbrega, Jakub T. Śliwiński, Thomas Ludwig, František Majs, William Nachlas, John H. Fournelle, Xavier Llovet, Rachelle B. Turnier, David Parcerisa, Anna Travé   +13 more
wiley   +1 more source