Results 161 to 170 of about 111,528 (283)

High continuous fragility index values for randomised controlled trials investigating medial patellofemoral ligament reconstruction for patellar instability: A systematic review

Knee Surgery, Sports Traumatology, Arthroscopy, Volume 34, Issue 2, Page 494-508, February 2026.
Abstract Purpose To evaluate the statistical fragility of randomised controlled trials (RCTs) investigating medial patellofemoral ligament reconstruction (MPFLR) of patients with patellar instability. Methods A search of PubMed, MEDLINE, and EMBASE databases for RCTs investigating surgical management of patients with patellar instability from inception
Dalraj Dhillon, Paary Balakumar, Prushoth Vivekanantha, Amit Meena, Shahbaz Malik, Darren de SA   +5 more
wiley   +1 more source

How to Use MRP in Continuous Production Industries When Order Type is Lot for Lot

International Journal of Industrial Engineering and Production Research, 2010
The Materials Requirements Planning (MRP) method that is applied in production planning and management has some weaknesses. One of its weaknesses is that the time in MRP method is discrete, and is considered as time period. Hence we are not able to order
Ramin Sadeghian
doaj  

An Electrically Tight In Vitro Blood–Brain Barrier Model Displays Net Brain-to-Blood Efflux of Substrates for the ABC Transporters, P-gp, Bcrp and Mrp-1

AAPS Journal, 2014
H. C. Helms, Maria Hersom, Louise Borella Kuhlmann, Lasina Badolo, C. Nielsen, B. Brodin   +5 more
semanticscholar   +1 more source

Tailored GelMA‐Chitosan‐Polypyrrole‐ CNT Conductive Scaffold for Potential Application in Neural Tissue Regeneration

Macromolecular Materials and Engineering, Volume 311, Issue 2, February 2026.
This study presents an optimal hydrogel that matches the physicochemical and biological properties of neural tissue. The presence of carbon nanotubes and polypyrrole in the GelMA‐chitosan matrix improved the biomechanical and bioelectric properties of the scaffold and increased the adhesion and viability of PC12 and SH‐SY5Y cells.
Pegah Madaninasab, Sheyda Labbaf, Hossein Salehi   +2 more
wiley   +1 more source

Metabolic reprogramming-driven stratification and therapeutic targeting in lung adenocarcinoma: implications for prognosis and personalized treatment. [PDF]

Front Oncol
Jia J, Feng S, Wang R, Zhao X, Cui Y.
europepmc   +1 more source

The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.

Journal of Biological Chemistry, 1994
I. Leier, G. Jedlitschky, U. Buchholz, S. Cole, R. Deeley, D. Keppler   +5 more
semanticscholar   +1 more source

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian, Jun Ge, Ni Fan, Zheng Sun, Chengcheng Zhao, Yujiao Sun, Yingpeng Li, Yunfei Li, Hui Fu   +8 more
wiley   +1 more source

Caylobolide B: Structure Revision, Total Synthesis, Biological Characterization, and Discovery of New Analogues

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
Marine polyhydroxylated macrolides’ drug discovery potential is limited by structural complexity and scarce material supply, hindering structure assignment, synthesis, and biological studies. Here, we present an integrated workflow that combines chemogenomic profiling, ultra‐high‐resolution NMR‐guided structural revision and stereochemical assignment ...
Malcolm R. P. George, Lobna A. Elsadek, Max Deering, Larissa Costa de Almeida, Jasper L. Tyler, Adam Noble, Valerie J. Paul, Hendrik Luesch, Craig P. Butts, Varinder K. Aggarwal   +9 more
wiley   +2 more sources

Fermented Soy Protein Maillard Product Prevents Bone Loss via TNF-α Suppression and Gut-Bone Axis Modulation in Ovariectomized Mice. [PDF]

J Microbiol Biotechnol
Bae HJ, Joung JY, Choi HS, Han JS, Kim JH, Kim JK, Oh NS.   +6 more
europepmc   +1 more source

State‐of‐the‐Art Strategies for Circular RNA in Cancers: Opportunity and Challenge

MedComm, Volume 7, Issue 2, February 2026.
Overview of circular RNA in tumors. ABSTRACT Circular RNAs (circRNAs) are characterized by their covalently closed structure, remarkable stability, and precise spatiotemporal regulation, evolving from once‐overlooked transcriptional byproducts to pivotal molecular regulators.
Zehao Ding, Zai Luo, Liao Zhang, Shaopeng Zhang, Renchao Zhang, Zhengjun Qiu, Chen Huang   +6 more
wiley   +1 more source