Results 121 to 130 of about 37,147 (232)

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

Tailored Hardening and Isothermal Bainitizing of Additively Manufactured Nitrogen‐Enhanced Martensitic Chromium Steel

steel research international, EarlyView.
Tailored heat treatments transform additively manufactured high‐nitrogen martensitic Cr steel from austenitic as‐built condition to high‐hardness states. Isothermal bainitizing at 250°C generates an ultrafine nanostructure and achieves higher hardness than conventional hardening and tempering, highlighting a promising postprocessing route for laser ...
Philip König, Sebastian Weber, Jonathan Lentz   +2 more
wiley   +1 more source

Multicellular immunosuppressive networks in microsatellite-stable colorectal cancer: CD8+ T cell exclusion, dysfunction, exhaustion, and therapeutic implications. [PDF]

Front Immunol
Xia Z, Chen H, Shen Y, Lin M, Xie X, Shu H, Pang S, Liu D, Cao Y, Zhang S.   +9 more
europepmc   +1 more source

Reconstruction of 3-D core flows using magnetic data from Swarm and MSS-1

Physics of the Earth and Planetary Interiors
Jinfeng Li, Yufeng Lin, Keke Zhang
openaire   +1 more source

Effects of Motivational Interventions on EFL Learners' Learning Effort and Achievement: An L2 Motivational Self System Perspective

TESOL Quarterly, EarlyView.
Abstract Grounded in the L2 motivational self system theory, this quasi‐experimental study investigated the impact of three motivational interventions on two outcome measures: L2 learning effort and L2 achievement. A total of 391 Chinese junior secondary students were assigned to four conditions: a control group receiving no motivational instruction ...
Xuejun Ye, Guangwei Hu
wiley   +1 more source

Heating the Cold: Overcoming Immunotherapy Resistance in Microsatellite-Stable Colorectal Cancer: A Systematic Review. [PDF]

Molecules
Bartusik-Aebisher D, Justin Raj DR, Wilk I, Aebisher D.   +3 more
europepmc   +1 more source

The polysaccharide Pullulan improves the initial steps of allergen‐specific immunotherapy in dogs

Veterinary Record, EarlyView.
Abstract Background Allergen‐specific immunotherapy (AIT) is the only aetiological treatment for canine atopic dermatitis (CAD). Pullulan, a polysaccharide with immunomodulatory properties, may enhance AIT outcomes when combined with allergens such as recombinant Dermatophagoides farinae 2 (Der f 2).
Franco Martini, Ana Rostaher, Claude Favrot, Nina M. Fischer   +3 more
wiley   +1 more source

Microsatellite instability combined with PD-L1 expression in prognosis of gastric cancer: an integrated analysis based on individual patient data. [PDF]

Front Oncol
Feng Y, Yin M, Chai J, Zhu J, Zhang Y, Wang K, Duan F.   +6 more
europepmc   +1 more source

The Chemical Effects of Nitrogenous Substances in Two Different Grades of PVDF Used in Offshore Applications

Journal of Vinyl and Additive Technology, EarlyView.
Proposed reaction schematic. ABSTRACT In this work, two different grades of poly(vinylidene fluoride) (PVDF) commonly used in offshore applications, one with 3% of dibutyl sebacate (DBS) plasticizer and the other a copolymer containing chlorotrifluoroethylene (CTFE), were subjected to an aging process in contact with a fluid containing hydrocarbons ...
Luiza M. S. S. de Oliveira, Frederico G. de A. Dias, Elaine F. Silva, Achilles J. B. Dutra, Marysilvia F. da Costa   +4 more
wiley   +1 more source

Muscle Spindle Alterations Following Ischemic Stroke and Peripheral Denervation in Murine Models. [PDF]

Int J Mol Sci
Sun Y, Zhao X, Fede C, Petrelli L, Morri G, Allegra M, Porzionato A, Stecco C.   +7 more
europepmc   +1 more source