Results 181 to 190 of about 36,668 (274)

Clinical‐Grade Human Induced Pluripotent Stem Cell‐Derived Neural Precursor Cells Restore Motor Function and Preserve Striatal Integrity in a Quinolinic Acid‐Lesioned Rat Model of Huntington's Disease

Cell Proliferation, EarlyView.
Clinical‐grade HLA‐homozygous iPSC‐derived neural precursor cells restore motor function, rebuild striatal circuitry and reduce neuroinflammation in QA‐lesioned rats. These findings demonstrate robust neuronal replacement and microenvironment modulation, supporting their potential as a regenerative therapy for Huntington's disease.
Hyeonjoong Jeon, Il‐Shin Lee, Sanghun Lee, Hyo Chang Park, Beomsoo Kim, Hyun Sook Kim, Jihwan Song   +6 more
wiley   +1 more source

Biomarker guided combination strategies and perioperative integration for immune cold microsatellite stable colorectal cancer. [PDF]

Discov Oncol
Yao N, Li W, Duan N, Han F, Yu G, Qu J.
europepmc   +1 more source

Epistolario de fray Diego Tadeo González (BNE, MSS/23306/1). Cartas a Gaspar Melchor de Jovellanos y a Miguel Miras, Oviedo, IFESXVIII / Ediciones Trea (ACESXVIII, 17), 2025.

Mayte Contreras Mira
openalex   +2 more sources

493 Akkermansia muciniphila reprograms immunosuppressive microenvironment via efferocytosis inhibition to sensitize anti-PD-1 therapy in MSS colorectal cancer: phase I trial [PDF]

Yuting Jiang, Guangqi Li, Xuelei Ma
openalex   +1 more source

Block scheduling in practice: An optimal decomposition strategy for nonidentical operating rooms

Decision Sciences, EarlyView.
Abstract We develop and implement a Master Surgery Schedule for a real‐life hospital, assigning operating room (OR) time to surgical specialties over a multi‐week horizon. Through action research, we identify a critical operational challenge: the issue of split blocks. Split blocks allow two specialties to share an OR on the same day—one in the morning,
Vincent J. J. van Ham, Alex Kuiper, Robert H. Lee   +2 more
wiley   +1 more source

Preparation of Uniform PEG-PLLA Microspheres via Membrane Emulsification for Soft Tissue Filling Applications. [PDF]

J Funct Biomater
Zhang S, Gao Y, Wang D, Chi Y, Wu F, Wang L, Jin H.   +6 more
europepmc   +1 more source

MSS-CT-5 (Train 1)

Yu Pengxin
openalex   +1 more source

PD‐1 blockade enhances the effect of targeted chemotherapy on locally advanced pMMR/MSS colorectal cancer [PDF]

Fengyun Pei, Wan He, Yinghua Duan, Qijun Yao, Yandong Zhao, Xinjuan Fan, Shuai Liu, Haiyang Chen, Fang He, Tingzhi Liu, Jiaoting Chen, Yijia Zheng, Heping Li, Xiaofang Guo, Lishuo Shi, Li Ling, Yaoxu Chen, Jia‐Peng He, Miao Liu, Mengli Huang, Mengli Huang, Yuezong Bai, Jian‐Ping Wang, Meijin Huang, Meijin Huang, Jun Huang   +25 more
openalex   +1 more source

Evaluating the Impact of Putative Metformin Targets on Cancer Outcomes: A Drug‐Target Mendelian Randomization Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Observational studies show metformin use associated with lower cancer risk, although experimental evidence is inconsistent. To provide genetic validation for repositioning of metformin in cancer prevention, we assessed genetically proxied effects of putative metformin targets on cancer outcomes using a drug‐target Mendelian randomization (
Xingyu Shen, Shan Luo, Jie Zheng, Celine Sze Ling Chui, Ian Chi Kei Wong, Eric Yuk Fai Wan, Catherine Mary Schooling, Shiu Lun Au Yeung   +7 more
wiley   +1 more source

Relationship of Photoplethysmography Morphological Variability Indices and Ankle-Brachial Index in Peripheral Artery Disease Patients. [PDF]

Sensors (Basel)
Hernández-Obín D, Torres-Machorro A, Lerma C.   +2 more
europepmc   +1 more source