Plasma metabolic signatures of healthy dietary patterns and risk of metabolic dysfunction-associated steatotic liver disease and cirrhosis. [PDF]
Wang S +12 more
europepmc +1 more source
Genetic testing in paediatric neurological disorders
In this study 390 paediatric patients with neurological disorders underwent genetic testing via exome sequencing, commercial panel, in‐house epilepsy, and movement disorder gene panels. Exome sequencing provides the highest diagnostic yield, and severe developmental delay and hypotonia predicted pathogenic variants in the exome sequencing cohort ...
Wafa Bani Uraba +15 more
wiley +1 more source
Traditional Chinese medicine as a potential barrier-oriented sensitization strategy for immune checkpoint blockade in microsatellite-stable colorectal cancer: from resistance mechanisms to translational validation. [PDF]
Wang D, Wang Y, Wang X.
europepmc +1 more source
Early tocilizumab and outcomes in acute necrotizing encephalopathy
Early tocilizumab and outcome in acute necrotising encephalopathy. Aim To evaluate the timing and safety of tocilizumab in acute necrotizing encephalopathy (ANE). Method This was a multicentre retrospective study evaluating outcomes (modified Rankin Scale [mRS]) in children with ANE treated with tocilizumab. A logistic regression model determined a cut‐
Velda X Han +14 more
wiley +1 more source
Characterizing Gynecological Cancers with the Uncommon dMMR/MSS Phenotype in Lynch Syndrome Patients. [PDF]
Koktsidis G +8 more
europepmc +1 more source
Abstract The 1430s were characterized by extreme weather conditions, food and fodder shortages, and high mortalities among animals and humans, although the severity of events and their consequences in England have received limited attention. The economic downturn and the depressed customary land market in this decade marked the beginning of the Great ...
Mark Bailey
wiley +1 more source
Impact of Dominant Species Shift in Herbaceous Vegetation Beneath Sand-Fixing Plantations on Soil Microbial Communities Involved in Organic P Mineralization and Inorganic P Solubilization. [PDF]
Li H, Zhang Y, Xiang Y, Cao C.
europepmc +1 more source
The Effects of Information Technologies on the Bankruptcy Decision
ABSTRACT Exploiting the staggered adoptions of electronic systems across 70 bankruptcy courts in the United States, I investigate the impacts of digital transformation on bankruptcy behavior. The digital transformation in bankruptcy courts significantly lowered the cost of filing by enabling debtors to file for bankruptcy online, yet empirical tests ...
Jeyul Yang
wiley +1 more source
The characteristics of gut microbiota in colorectal cancer with different microsatellite states. [PDF]
Yao Y +5 more
europepmc +1 more source
This meta‐analysis demonstrates that high‐grade tumour budding is an independent prognostic factor in stage II–III colorectal cancer, associated with significantly worse disease‐free survival, overall survival and cancer‐specific survival. Aims Tumour budding (TB) has been recognized as an additional prognostic factor in the TNM (2017) and WHO (2019 ...
Yao Shu +4 more
wiley +1 more source

