Comparison and analysis of the immune landscape at the tumour invasion front in patients with pMMR/MSI-H and pMMR/MSS colorectal cancer. [PDF]
Shen M +5 more
europepmc +1 more source
Compartment‐guided assembly of large‐scale molecular models with Bentopy
Abstract Molecular dynamics simulations of whole cells and organelles aim to transform cell biology by providing a molecular view into the crowded cellular environment. However, constructing suitable starting configurations remains a major bottleneck due to their size and complexity.
M. S. S. Westendorp +6 more
wiley +1 more source
Impact of liver metastasis on the efficacy of immune checkpoint inhibitors for advanced colorectal cancer. [PDF]
Xiang MY +5 more
europepmc +1 more source
Examination of the Characteristics and Relevant Physical Factors Associated with Persistent Falls in Community-Dwelling Older Adults: An Exploratory Prospective Cohort Study. [PDF]
Morimoto Y +6 more
europepmc +1 more source
Deep Dermal and Subcutaneous Deposits in Thin Melanoma: A Cautionary Tale
ABSTRACT Melanoma microsatellites are peritumoral metastatic deposits and surrogates for potentially aggressive biological behavior. Their presence indicates clinical stage III disease. They are rarely reported in association with thin primary tumors (< 1.0 mm, pT1).
Angela Cheng +5 more
wiley +1 more source
Mutation and Microsatellite Instability (MSI) Affect the Differential Gene Expression of Folic Acid and 5-Flourouracil Metabolism-Related Genes in Colorectal Carcinoma. [PDF]
Islam MR +6 more
europepmc +1 more source
Cave environments filter plant traits, selecting thinner, smaller leaves with reduced photosynthetic and vascular structures. Abstract Caves present unique ecological conditions that influence the distribution and adaptation of species, yet studies on cave‐associated vegetation remain limited.
G. H. Rosa +3 more
wiley +1 more source
Transcriptomic-guided whole-slide image classification for molecular subtype identification. [PDF]
Wang W, Zhang X, Xiong Y.
europepmc +1 more source
The secreted redox sensor roGFP2‐Orp1 reveals oxidative dynamics in the plant apoplast
Using the secreted redox biosensor roGFP2‐Orp1, we reveal differences in extracellular (apoplastic) oxidative processes between and within species, depending on cell type and immune signalling. Abstract Specific generation of reactive oxygen species (ROS) is important for signalling and defence in many organisms. In plants, different types of ROS serve
J. Ingelfinger +8 more
wiley +1 more source
Malnutrition and sarcopenia: a combined risk factor for vascular calcification and cardiovascular events in hemodialysis patients. [PDF]
Wang Z +6 more
europepmc +1 more source

