Results 231 to 240 of about 24,399,079 (272)

A comparison by mismatch repair status of real‐world characteristics and outcomes in patients with stage II/III rectal cancer in the Netherlands

International Journal of Cancer, Volume 158, Issue 4, Page 963-976, 15 February 2026.
What's new? Mismatch repair deficiency (dMMR) in rectal cancer is rare, and knowledge about tumor biological behavior, response to treatment, and clinical outcomes in this subset of patients is limited. This nationwide cohort study including 182 patients with dMMR rectal cancer found that they were younger and had more poorly differentiated tumors ...
Renee A. Lunenberg, Ingrid A. Franken, Frederieke H. van der Baan, Femke P. C. Sijtsma, Geraldine R. Vink, Manon N. G. J. A. Braat, Leon M. G. Moons, Miangela M. Lacle, Marloes A. G. Elferink, Susan Boklage, Martijn P. W. Intven, Jamie Garside, Miriam Koopman, Rob van Wuijtswinkel, Jeanine M. L. Roodhart   +14 more
wiley   +1 more source

Camrelizumab plus albumin-bound paclitaxel and S-1 as first-line treatment for patients with human epidermal growth factor receptor 2-negative advanced gastric or gastroesophageal junction adenocarcinoma: a phase 2 trial. [PDF]

Front Immunol
Wu C, Li S, Hou X.
europepmc   +1 more source

Tailored Xenogeneic‐Free Polymer Surface Promotes Dynamic Migration of Intestinal Stem Cells

Advanced Materials, Volume 38, Issue 8, 6 February 2026.
This study introduces a PoLymer‐coated Ultra‐stable Surface (PLUS), a nitrogen plasma‐treated poly(ethyleneglycoldimethacrylate), as a stable xenogeneic‐free platform for intestinal stem cell culture. PLUS enhances cell attachment, supports actin‐driven migration, and retains functionality after 3 years of storage. Promoting cytoskeletal reorganization,
Seonghyeon Park, Sang Yu Sun, Jin Gyeong Son, Sun Young Lee, Hyun Kyong Shon, Ohman Kwon, Minseok Lee, Keonwoo Choi, Jemin Yeun, Sung Hyun Yoon, Minkyung Kim, Mi‐Young Son, Tae Geol Lee, Sung Gap Im   +13 more
wiley   +1 more source

Current and emerging concepts for systemic treatment of metastatic colorectal cancer. [PDF]

Gut
Steup C, Kennel KB, Neurath MF, Fichtner-Feigl S, Greten FR.   +4 more
europepmc   +1 more source

Terahertz Waveform‐Selective Antenna Using a Patch Structure Loaded with Nonlinear Circuits

Advanced Photonics Research, Volume 7, Issue 2, February 2026.
A waveform‐selective antenna that integrates the functions of waveform selectivity, electromagnetic shielding, and EM wave radiation has been proposed. By integrating different nonlinear circuits and selecting appropriate component values, the antenna can achieve high reflection of either a pulse wave or a continuous wave, while allowing the other ...
Zeting Li, Kai‐Da Xu, Pin Wen
wiley   +1 more source

Medical student syndrome among medical and nonmedical students at Sultan Qaboos University: A comparative study of health anxiety. [PDF]

J Educ Health Promot
Al Lawati A, Alhadithy Z, Al Abri GN, Al Lawati GS, Al Azri MI, Al-Mahrouqi T, Al-Mufargi Y, Al Sinawi H.   +7 more
europepmc   +1 more source

Subacute Thyroiditis Diagnosed by Targeted Anterior Neck Examination

Journal of General and Family Medicine, Volume 27, Issue 2, March 2026.
Ryuichi Minoda Sada, Saki Sada Minoda
wiley   +1 more source

Three‐Year Follow‐Up of Neoadjuvant Tislelizumab with Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Adenocarcinoma: Revealing Cancer‐Associated Fibroblast Heterogeneity Corresponding to PD‐1 Blockade Efficacy

Advanced Science, Volume 13, Issue 9, 13 February 2026.
Heterogeneous cancer‐associated fibroblasts orchestrate dual immune microenvironments in LAGC. Abstract The potential for immunotherapy in patients with locally advanced gastric cancer (LAGC) is recently confirmed. To report the 3‐year follow‐up data are aimed from a novel clinical trial. This is a prospective single‐arm phase II trial.
Yao Lin, Xiong Sun, Chengguo Li, Ming Yang, Ke Wu, Ke Liu, Anshu Li, Xiaoming Shuai, Kailin Cai, Zheng Wang, Guobin Wang, Peng Zhang, Jianfeng Shen, Kaixiong Tao, Yuping Yin   +14 more
wiley   +1 more source

The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer

Advanced Science, Volume 13, Issue 9, 13 February 2026.
In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu, Jing Xun, Bin Liu, Xiaolin Jiang, Yingdi Han, Huichao Yang, Qi Gao, Ruifang Gao, Aimin Zhang, Xueliang Wu, Dapeng Zhang, Dihua Li, Tian Li, Shimin Yang, Ximo Wang, Xiangyang Yu, Qi Zhang   +16 more
wiley   +1 more source

Cathepsin-D-mediated MHC class I degradation contributes to immune evasion in colorectal cancer. [PDF]

Cell Rep Med
Zhan W, Fu Y, Liu Y, Cai R, Bai F, Guo C, Cheng Y, Wu Z, Qin G, Xie Y, Zhang J, Deng Y.   +11 more
europepmc   +1 more source