Results 241 to 250 of about 24,399,079 (272)

Colorectal Cancer Organoid Model Reveals the Mechanisms of Irinotecan Resistance at Single‐Cell Resolution

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Objective Irinotecan, a standard therapeutic agent for metastatic colorectal cancer (mCRC), often faces significant limitations due to drug resistance, with treatment failure observed in approximately 30%–50% of patients, leading to poor clinical outcomes.
Yi Pan, Lin Chen, Yuqing Hu, Jie Chang, Xifeng Xu, ShuoChen Xu, YiWen Li, Jinlin Du, JianPing Wang, Wenxia Xu   +9 more
wiley   +1 more source

High-dimensional strain unlocks fast polysulfide redox kinetics for lithium-sulfur batteries. [PDF]

Nat Commun
Yang JL, Xu H, Xiao T, Li J, Yan W, Zhang T, Fan HJ.   +6 more
europepmc   +1 more source

Internal closure of a posterior perforation using amniotic membrane: A novel surgical technique

Acta Ophthalmologica, Volume 104, Issue 2, Page 236-238, March 2026.
J. S. Suwandi, B. A. van der Wel, E. H. C. van Dijk, S. S. Manning, M. Manzulli, P. Geeraert, S. van Romunde, K. Faridpooya   +7 more
wiley   +1 more source

Isoflavonoids and Epigenetic Modulation: Therapeutic Insights for Cancer Treatment

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
Venn diagram illustrating the epigenetic roles of three phytochemical groups—flavonoids, isoflavonoids, and pterocarpans. ABSTRACT Isolavonoides represent the second largest subgroup of flavonoids and have an influence on critical molecular pathways and restore cellular homeostasis, through the reprogramming of epigenetic regulatory mechanisms.
Eduardo de Moraes e Sousa, Maria Claudia dos Santos Luciano, Gabriel Caetano de Souza, Maria Francilene Souza Silva, Fátima de Cássia Evangelista de Oliveira, Sarah Sant'Anna Maranhão, Felipe Vasconcelos, Cristiana Libardi Miranda Furtado, Claudia do Ó Pessoa   +8 more
wiley   +1 more source

Marinesco-Sjögren Syndrome: A Novel <i>SIL1</i> Variant with In Silico Analysis and Review of the Literature. [PDF]

Life (Basel)
Aslan ES, Eslamkhah S, Akcali N, Yavas C, Karcioglu Batur L, Sengenc E, Yüksel A.   +6 more
europepmc   +1 more source

A Machine Learning-Based Scoring System to Identify High Immunoactivity Microsatellite Stability Tumors by Quantifying Similarity to Microsatellite Instability-High Tumors in Colorectal Cancers: Development and Quantitative Study. [PDF]

JMIR Form Res
Yan H, Jiang L, Li Y, Wang F, Mo S, Sheng W, Huang D, Peng J.   +7 more
europepmc   +1 more source

A Cross-Layer Framework Integrating RF and OWC with Dynamic Modulation Scheme Selection for 6G Networks. [PDF]

Sensors (Basel)
Waheed A, Genoves Guzman B, Mohammady S, Brandt-Pearce M.   +3 more
europepmc   +1 more source

Emerging role of DNA polymerase epsilon non-exonuclease domain mutations in colorectal cancer: From sequence variants to clinical implications. [PDF]

World J Gastroenterol
Xu JJ, Ni CX, Xu JJ.
europepmc   +1 more source

LOX1-mediated supramolecular self-assembly nanomedicine for microsatellite-stable colorectal cancer towards reactivating anti-tumor immunity. [PDF]

Front Immunol
Wei X, Guo Y, Lei J, Chen N.
europepmc   +1 more source

Deciphering mismatch repair protein expression variability in gastric cancer: clinical and prognostic implications. [PDF]

BMC Cancer
Zhong F, Zhang M, Xu L, Cui J, Chen Z, Gao Q.   +5 more
europepmc   +1 more source