Results 51 to 60 of about 24,399,079 (272)

Ferguson, Champ, 1821-1865 (MSS 1) [PDF]

, 2008
Finding aid only for Manuscripts Collection 1. An account of Ferguson\u27s military trial for murders committed during the Civil War by him and his band of outlaws, held at Nashville, Tennessee.
Folklife Archives, Manuscripts &
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Inhalable Nano-Dimpled Microspheres Containing Budesonide-PLGA for Improved Aerodynamic Performance

International Journal of Nanomedicine, 2022
Chang-Soo Han,1,* Ji-Hyun Kang,1,* Young-Jin Kim,1 Dong-Wook Kim,2 Chun-Woong Park1 1College of Pharmacy, Chungbuk National University, Cheongju, 28160, Republic of Korea; 2College of Pharmacy, Wonkwang University, Iksan, 54538, Republic of Korea&
Han CS, Kang JH, Kim YJ, Kim DW, Park CW
doaj  

Nanocrystalline cellulose derived from melon seed shell (Citrullus colocynthis L.) for reduction and stabilization of silver nanoparticles: Synthesis and catalytic activity

Carbohydrate Polymer Technologies and Applications, 2021
Melon seed shells (MSS) are a hazard to the environment as they host disease vectors. To alleviate the effect, we explored melon seed shells (MSS) as a new source of nanocrystalline cellulose (NCC) with reducing- and stabilizing capacity for the ...
Segun A. Ogundare, Vashen Moodley, James F. Amaku, Abdulrazaq O. Ogunmoye, Odunayo C. Atewolara-Odule, Oseyemi O. Olubomehin, Kehinde N. Awokoya, Nurudeen O. Sanyaolu, Adeola A. Ibikunle, Werner E. van Zyl   +9 more
doaj   +1 more source

Phase II study of durvalumab (anti-PD-L1) and trametinib (MEKi) in microsatellite stable (MSS) metastatic colorectal cancer (mCRC)

Journal for ImmunoTherapy of Cancer, 2022
Background Monotherapy with immune checkpoint blockade is ineffective for patients (pts) with microsatellite stable (MSS) metastatic colorectal cancer (mCRC). This study investigates whether the combination of trametinib (T) with durvalumab (D) can alter
B. Johnson, C. Haymaker, E. Parra, L. Soto, Xuemei Wang, Jane V. Thomas, A. Dasari, V. Morris, K. Raghav, E. Vilar, B. Kee, C. Eng, C. Parseghian, R. Wolff, Younghee Lee, D. Lorenzini, Caddie Laberiano-Fernández, A. Verma, W. Lang, I. Wistuba, A. Futreal, S. Kopetz, M. Overman   +22 more
semanticscholar   +1 more source

A new approach toward geometrical concept of black hole thermodynamics [PDF]

, 2015
Motivated by the energy representation of Riemannian metric, in this paper we study different approaches toward the geometrical concept of black hole thermodynamics.
Hendi, S. H., Momennia, M., Panah, B. Elam, Panahiyan, S.   +3 more
core   +2 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

A Cost-Effectiveness Analysis of First Trimester Non-Invasive Prenatal Screening for Fetal Trisomies in the United States. [PDF]

PLoS ONE, 2015
Non-invasive prenatal testing (NIPT) is a relatively new technology for diagnosis of fetal aneuploidies. NIPT is more accurate than conventional maternal serum screening (MSS) but is also more costly.
Brandon S Walker, Richard E Nelson, Brian R Jackson, David G Grenache, Edward R Ashwood, Robert L Schmidt   +5 more
doaj   +1 more source

Radioactive Probes of the Supernova-Contaminated Solar Nebula: Evidence that the Sun was Born in a Cluster [PDF]

, 2006
We construct a simple model for radioisotopic enrichment of the protosolar nebula by injection from a nearby supernova, based on the inverse square law for ejecta dispersion.
Brian D. Fields, Cosarinsky M., Hauri E. H., John J. Tobin, Kleine T., Kleine T., Leslie W. Looney, Meyer B. S., Meyer B. S., Nyquist L. E., Yorke H. W., Young E. D.   +11 more
core   +3 more sources