PPARγ induces PD-L1 expression in MSS+ colorectal cancer cells
OncoImmunology, 2021 Only a small subset of colorectal cancer (CRC) patients benefits from immunotherapies, comprising blocking antibodies (Abs) against checkpoint receptor “programmed-cell-death-1” (PD1) and its ligand (PD-L1), because most cases lack the required ...
Tobias Gutting +21 more
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Tumor mutational burden predicts neoantigen profiles and immunotherapy response in microsatellite stable tumors across different cancer types [PDF]
Frontiers in ImmunologyIntroductionImmunotherapy has shown positive response in many patients with microsatellite instable (MSI-H) tumors, but its effectiveness in microsatellite stable (MSS) tumors remains limited.
Olesia Kondrateva +7 more
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Enhanced behavior of solar stills with modified absorber surfaces: Comparative analysis of floating wick designs [PDF]
E3S Web of Conferences, 2023 Different shaped floating wick (FW) material in the basin improved the efficacy of a single slope solar still (SS). Thermocol is used to support a basin in which cotton wicks are suspended.
Kannakumar K. +6 more
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Analysis of the Development of Abnormal Grains Structures During Beta Annealing of Ti-64 Wrought Products [PDF]
MATEC Web of Conferences, 2020 The ß-annealing of Titanium-6Al-4V (Ti64) wrought aerospace components can lead to the development of abnormal grain structures (AGS) that jeopardise material performance.
Byres Nicholas E. +5 more
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Research Progress on Combined Immunotherapy for Microsatellite Stable Colorectal Cancer
Zhongliu Fangzhi Yanjiu, 2022 In recent years, immunotherapy has achieved great progress in the treatment of malignant tumors and has enriched the treatment mode of many types of malignant tumors. Colorectal cancer is a common tumor worldwide.
YIN Zhucheng, LIANG Xinjun
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Consilium Medicum, 2022 Aim. The pooled efficacy data of two similar randomized placebo-controlled clinical trials were analyzed. Safety was evaluated on the basis of the individual trials. Materials and methods. The efficacy analysis was based on 589 patients.
Rainer Jund +4 more
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The road to incorporating Scottish pelagic industry data in science for stock assessments
Frontiers in Marine Science, 2023 Fisheries data collection through industry-science partnerships have significant potential to support stock assessments and sustainable management, but few studies have described the steps taken en route to a successful partnership.
Steven Mackinson +5 more
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Vìsnik - Kiïvsʹkij nacìonalʹnij unìversitet ìmenì Tarasa Ševčenka: Ìstorìâ, 2020 The author of the article investigates the merits and remuneration of employees of the regional and city depatments of the NKGB-MSS in the Ternopil region in the 1945-1948 on the basis of a considerable circle of historical sources and monographs.
Roman Pyrozhyshyn
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Traffic agents for improving QoS in mixed infrastructure and ad hoc modes wireless LAN [PDF]
, 2006 As an important complement to infrastructured wireless networks, mobile ad hoc networks (MANET) are more flexible in providing wireless access services, but more difficult in meeting different quality of service (QoS) requirements for mobile customers ...
A Hills +17 more
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A new Arctic MSS model derived from combined Cryosat-2 and ICESat observations
International Journal of Digital Earth, 2022 Due to the existence of seasonal or perennial sea ice cover, the determination of the Arctic sea surface is more difficult than that of mid-low latitudinal oceans.
Guodong Chen +5 more
doaj +1 more source