Results 51 to 60 of about 316,599 (309)
Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease
Advanced Science, EarlyView.ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan +17 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu +12 more
wiley +1 more source
Occupational challenges in nursing: a qualitative study from Bangladesh
Discover Public HealthPurpose Nursing is one of the most challenging professions in healthcare as nurses face numerous challenges while delivering healthcare services in hospitals.
Shahinur Akter +3 more
doaj +1 more source
A Stone-Weierstrass theorem for group representations
International Journal of Mathematics and Mathematical Sciences, 1978 It is well known that if G is a compact group and π a faithful (unitary) representation, then each irreducible representation of G occurs in the tensor product of some number of copies of π and its contragredient. We generalize this result to a separable
Joe Repka
doaj +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Invertebrate communities from the mesovoid shallow substratum of the Carpatho-Euxinic area
Travaux de l'Institut de Speologie Emile Racovitza, 2010 Between 1998 and 2008, the authors analyzed from a faunistic and zoogeographic point of view, 5 sites with different types of mesovoid shallow subtratum (MSS) from the karst areas of Dobrogea and the Carpathians.
EUGEN NITZU +3 more
doaj
Hematology, Transfusion and Cell TherapyObjetivos: Este artigo de revisão tem como objetivo explorar a utilização da citometria de fluxo na caracterização de células imunes em pacientes com cardiomiopatia hipertrófica (CMH).
MSS Pereira
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Colorectal cancer (CRC) remains therapeutically challenging due to high metastasis, recurrence, and immunotherapy resistance driven by tumor microenvironment‐mediated immune evasion. Immunogenic cell death (ICD) offers a promising strategy to reshape the immune microenvironment, yet existing ICD inducers suffer from poor targeting efficiency ...
Yao Xiao +12 more
wiley +1 more source
An efficient decomposition approach for surgical planning [PDF]
, 2012 This talk presents an efficient decomposition approach to surgical planning. Given a set of surgical waiting lists (one for each discipline) and an operating theater, the problem is to decide the room-to-discipline assignment for the next planning period
Agnetis, Alessandro +5 more
core
Hematology, Transfusion and Cell TherapyObjetivos: Este artigo visa revisar a eficácia do Patient Blood Management (PBM) na redução de transfusões sanguíneas em pacientes com insuficiência cardíaca avançada. O PBM é uma abordagem multidisciplinar que busca otimizar o uso do sangue do paciente,
MSS Pereira
doaj +1 more source