Results 91 to 100 of about 202,264 (382)

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source

Budapest városfejlesztés aktuális kérdései az MTA Közlekedés- és Járműtudományi Bizottságának üléséről [PDF]

, 2021
Balázs Horváth, Ádám Török
openalex   +1 more source

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

Comparative evaluation of fracture resistance of simulated immature teeth and its effect on single visit apexification versus complete obturation using MTA and biodentine

Journal of Family Medicine and Primary Care, 2020
Aim and Objectives: This study sought to evaluate and compare the fractured resistance of simulated immature teeth and the effect of single visit apexification versus complete obturation using MTA and biodentine.
Pawan Darak, Manoj Likhitkar, Shachi Goenka, Abhinav Kumar, Priyanka Madale, Ashwini Kelode   +5 more
doaj   +1 more source

Antimicrobial and antibiofilm activities of MTA supplemented with bismuth lipophilic nanoparticles.

Dental materials journal, 2017
The objective of this work was to determine the antimicrobial and antibiofilm properties of mineral trioxide aggregate (MTA) supplemented with bismuth lipophilic nanoparticles (BisBAL NPs).
R. Hernandez-Delgadillo, C. del Angel-Mosqueda, J. Solís-Soto, Silvia Munguía-Moreno, Nayely Pineda-Aguilar, R. I. Sánchez-Nájera, S. Chellam, C. Cabral-Romero   +7 more
semanticscholar   +1 more source

Spatio‐Temporal Proteomic Landscape Reveals Early Warning Signals of Esophageal Squamous Cell Carcinoma Progression

Advanced Science, EarlyView.
This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li, Jie Yuan, Min Gao, Jibin Liu, Qinqin Wang, Yaqi Zhang, Mingtao Cao, Xiaolin Hu, Hui Yang, Jun Li, Chen Li, Xiaoguang Li, Hui Wang   +12 more
wiley   +1 more source

Investigating in vitro Effect of Endodontic Calcium Silicate-based Biomaterials on the Human Cell Survival: A Systematic Review [PDF]

Journal of Mazandaran University of Medical Sciences, 2023
Background and purpose: The use of biomaterials in restorative dentistry is receiving increasing attention. In the treatment of living pulp, calcium silicate-based materials are used, the most common of which are MTA, biodentine, and CEM Cement.
Sahar Shabani Panbeh Choleh, Mahmoud Heidari, Ezatolah Kazeminejad, Masoud Mohammadi, Abdolhalim Rajabi   +4 more
doaj  

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

In vitro comparative study of apical microfiltration in retrograde fillings between dental cements: MTA Repair Hp and Biodentine

Salud Uninorte, 2018
Objetivo: Comparar "in vitro" el grado de microfiltración bacteriana en el tercio apical del conducto radicular, al realizar la técnica de obturación retrógrada mediante el uso de dos cementos endodónticos: el MTA Repair Hp (Angellus) y el Biodentine ...
María Fernanda Ramos Delgado, Silvia Cárdenas, Dunier Arias Socarràs, Sandra Cruz Quintana   +3 more
doaj  

Comparative Analysis of Cytotoxicity and Odontogenic Differentiation of Novel Bioceramic Material on Human Dental Pulp Stem Cells – An In Vitro Study

Journal of Pharmacy and Bioallied Sciences
Background and Objective: Bioceramic materials have revolutionized the field of endodontics by successfully transforming the outcomes of pulp therapies.
G. R. Ishwarya Dhevi, Ponnudurai Arangannal, J Jeevarathan   +2 more
doaj   +1 more source