Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian +9 more
wiley +1 more source
Microleakage Evaluation Around Retrograde Filling Materials Prepared Using Conventional and Ultrasonic Techniques [PDF]
Introduction: The importance of the retrograde cavity preparation and the material used to restore is of utmost importance to achieve successful surgical endodontics. Aim: The aim of the present study is to evaluate the apical microleakage of root end
Pragna Mandava +4 more
doaj +1 more source
Simulations of the anisotropic kinetic and magnetic alpha effects
The validity of a closure called the minimal tau approximation (MTA), is tested in the context of dynamo theory, wherein triple correlations are assumed to provide relaxation of the turbulent electromotive force. Under MTA, the alpha effect in mean field
Bhattacharjee +19 more
core +2 more sources
Introduction This in vitro study investigated the dislodgement resistance of EndoSeal MTA, a new pozzolan-containing calcium silicate-based material, in comparison with ProRoot MTA and Biodentine in the presence and absence of contamination with blood ...
A. Adl +2 more
semanticscholar +1 more source
Associations of Sleep and Shift Work with Osteoarthritis Risk
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships between circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000‐person cohort, we evaluated associations between sleep duration, sleeplessness/insomnia, and ...
Elizabeth L. Yanik +5 more
wiley +1 more source
Evaluation of Antimicrobial Activity of Mineral Trioxide Aggregate (MTA) [PDF]
Aims: To evaluate the antimicrobial activity of MTA against selected microorganisms compared with awidely used root end filling materials. Materials and methods: Fifteen mm discs of MTA, GIC andAmalgam were prepared and three types of microorganisms; two
Mahmoud Y Taha +2 more
doaj +1 more source
Histological and Immunohistochemical Evaluation of Biphasic Calcium Phosphate and a Mineral Trioxide Aggregate for Bone Healing in Rat Calvaria [PDF]
This work focused on the process of bone repair of defects in standardized calvaria of Wistar rats treated with biphasic calcium phosphate (BCP), mineral trioxide aggregate (MTA), or a combination of the two.
Almeida, Luis Eduardo +5 more
core +1 more source
Weighing the Local Group in the Presence of Dark Energy [PDF]
We revise the mass estimate of the Local Group (LG) when Dark Energy (in the form of the Cosmological Constant) is incorporated into the Timing Argument (TA) mass estimator for the Local Group (LG).
Hoffman, Yehuda +2 more
core +1 more source
Harmonization of space-borne infra-red sensors measuring sea surface temperature [PDF]
Sea surface temperature (SST) is observed by a constellation of sensors, and SST retrievals are commonly combined into gridded SST analyses and climate data records (CDRs).
Block, Thomas +5 more
core +1 more source
X‐Ray Tomography Analysis of Damage Mechanisms in Metal Matrix Syntactic Foams During Compression
In situ synchrotron X‐ray tomography is used to investigate the internal damage mechanisms of AlSi12 metal matrix syntactic foam with ceramic hollow spheres during compressive loading. It is concluded that a homogeneous distribution of the second‐phase filler material results in a sequential collapse in a localized region; this leads to controlled and ...
Indrajeet Tambe +8 more
wiley +1 more source

