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Inhibiting mTTR Aggregation/Fibrillation by a Chaperone-like Hydrophobic Amino Acid-Conjugated SPION
Journal of Physical Chemistry B, 2022Transthyretin (TTR) aggregation via misfolding of a mutant or wild-type protein leads to systemic or partial amyloidosis (ATTR). Here, we utilized variable biophysical assays to characterize two distinct aggregation pathways for mTTR (a synthesized monomer TTR incapable of association into a tetramer) at pH 4.3 and also pH 7.4 with agitation, referred ...
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Research on MTTR Allocation of Commercial Aircraft
2020 Global Reliability and Prognostics and Health Management (PHM-Shanghai), 2020Maintainability is always the key to the commercial success of commercial aircraft and directly affects the economy and market competitiveness. The target value of maintainability indexes of each system or equipment of the aircraft shall be determined by aircraft-level maintainability index allocation.
Zheng Wang, Linlong Ma, Xixi Yan
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Equipment MTTR Demonstration Method Based on Virtual Simulation
Applied Mechanics and Materials, 2013Aiming at the disadvantage of existing equipment MTTR demonstration method, this paper studied the project of equipment maintainability demonstration Based on Virtual Simulation, and put forward a method of equipment MTTR demonstration in the virtual environment, at last power system of equipment is verified as an example.
Xi Wu, Da Xu, Bao Qi Wang, Ge Mu
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The (α, β)-Precise Estimates of MTBF and MTTR: Definition, Calculation, and Observation Time
IEEE Transactions on Automation Science and Engineering, 2021The mean time between failures (MTBF) and mean time to repair (MTTR) of manufacturing equipment (e.g., machines) are used in every quantitative method for production systems performance analysis, continuous improvement, and design. Unfortunately, the literature offers no methods for evaluating the smallest number of up- and downtime measurements ...
Pooya Alavian, Yongsoon Eun, Kang Liu
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Researches on integrated evaluation methods for military aircraft's MTTR
The Proceedings of 2011 9th International Conference on Reliability, Maintainability and Safety, 2011Exerting combat efficiency of military aircraft relies heavily on its own quality characteristics, such as reliability, maintainability and supportability. Reducing aircraft's Mean Time To Repair (MTTR) is one of the significant targets for the maintenance of military aircraft to concern.
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Availability, MTBF and MTTR for Repairable M out of N System
IEEE Transactions on Reliability, 1981The availability of a redundant system requiring m out of n units to be operational represents a basic and elementary result within reliability engineering. The corresponding mean time between system failures (MTBF) and mean time of system restoral (MTTR) are less commonly known since these results have either required the solution of time-dependent ...
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Multi-MTTR Asynchronous-Asymmetric Channel-Hopping Sequences for Scalable Cognitive Radio Networks
IEEE Transactions on Cognitive Communications and Networking, 2018In this paper, a family of channel-hopping (CH) sequences, so-called multi-maximum time-to-rendezvous (MTTR) asynchronous-asymmetric prime sequences (MAAPSs), for cognitive radio networks (CRNs) is designed and analyzed. They have known and enlarged cardinality (for the benefit of user identification), full degree of rendezvous, and pairwise shift ...
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