Results 111 to 120 of about 116,093,450 (283)

Histopathological and ultrastructural evaluations of giant African snail (Achatina fulica) mucin and alginate hydrogel on cutaneous wound healing in rats

open access: yesOpen Veterinary Journal
Background: Wound healing is a complex biological process that involves inflammation, cellular proliferation, and tissue remodeling. Efficient and prompt wound repair is critical for infection prevention and tissue integrity restoration.
Mohammad Reza Salahi   +4 more
doaj   +1 more source

Follicular Adenoma with Extensive Extracellular Mucin Deposition: Report on Two Cases

open access: yesClinical Medicine Insights: Case Reports, 2012
We report two cases of follicular adenoma of the thyroid with extensive extracellular mucin deposition. Fine needle aspiration in Case 1 showed singly discohesive polygonal cells in a granular mucinous background.
Na Rae Kim   +5 more
doaj   +1 more source

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

open access: yesAdvanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin   +13 more
wiley   +1 more source

Differential expression of mucin 1 and mucin 2 in colorectal cancer

open access: yesWorld Journal of Gastroenterology, 2018
To determine tissue expression (mRNA, protein) of two types of mucins [mucin 1 (MUC1) and mucin 2 (MUC2)] in patients with colorectal cancer (CRC).Expression of membrane-bound mucin (MUC1) and secretory mucin (MUC2) in CRC (mRNA, protein) were analyzed in tissue material including fragments of tumors obtained from CRC patients (n = 34), and fragments ...
Kasprzak, Aldona   +6 more
openaire   +2 more sources

Induction of mucin expression by estrogen and lipopolysaccharide in the lower oviductal segments in hens.

open access: yes, 2013
Mucins play an essential role as mucosal barrier to prevent invasion of pathogens in the oviductal tissue of hens. The aim of this study was to determine the effect of estradiol and lipopolysaccharide (LPS) on the mucin expression in the lower oviductal ...
Isobe, Naoki   +2 more
core  

Determination of Gene‐Level Fitness Contributions Across the Mucin‐Utilization Network of Bacteroides thetaiotaomicron

open access: yesAdvanced Science, EarlyView.
Genome‐wide CRISPRi and RNA‐seq resolve how B. thetaiotaomicron converts host mucosal glycans into fitness. The study reveals a layered mucin‐utilization architecture in which capsular polysaccharides constrain surface access, extracellular CAZymes and peptidases show functional redundancy, and intracellular catabolic pathways create discrete metabolic
Kangsan Kim   +5 more
wiley   +1 more source

Hybrid CaCO3-mucin crystals: Effective approach for loading and controlled release of cationic drugs

open access: yesMaterials & Design, 2019
Vaterite CaCO3 crystals are actively used as a biocompatible and degradable matrix for encapsulation of fragile biomacromolecules. However, the incorporation of small cationic drugs into the crystals remains awkward due to a poor binding of these drugs ...
Nadezhda G. Balabushevich   +5 more
doaj   +1 more source

SIgA Binding to Mucosal Surfaces Is Mediated by Mucin-Mucin Interactions [PDF]

open access: yes, 2015
The oral mucosal pellicle is a layer of absorbed salivary proteins, including secretory IgA (SIgA), bound onto the surface of oral epithelial cells and is a useful model for all mucosal surfaces.
Wilson, Stephen   +18 more
core   +2 more sources

Oral Astilbin Nanogels Modulate Senescence‐Associated CD4+ T Cells and Promote Treg Induction in Aged Mice with Colitis

open access: yesAdvanced Science, EarlyView.
Fluorinated β‐glucan/pectin nanogels enable colon‐targeted oral delivery of astilbin through gastrointestinal protection, β‐glucanase‐responsive release, mucus penetration, and prolonged retention. The released astilbin attenuates senescence‐associated features of CD4+ T cells and promotes Treg responses, while the nanogel matrix modulates the gut ...
Lei Zhao   +11 more
wiley   +1 more source

ELF5‐Mediated Enhancer–Promoter Interaction Regulates LALBA Expression in Ovine Mammary Gland

open access: yesAdvanced Science, EarlyView.
In the study, we systematically investigate the epigenetic mechanisms underlying lactation traits in sheep by integrating transcriptomic, chromatin accessibility, histone modification, and functional analyses. We identify a super‐enhancer at the LALBA locus and demonstrate that enhancer E4 functions as its core regulatory element.
Xinmiao Wu   +11 more
wiley   +1 more source

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