Results 1 to 10 of about 29,433 (206)

Identification and characterisation of mucin abnormalities in the ganglionic bowel in Hirschsprung's disease [PDF]

open access: yes, 2010
MDHirschsprung’s disease (HD) is a congenital abnormality of unknown origin, characterised by a lack of ganglion cells in the distal colon which results in functional colonic obstruction.
Speare, Ruth Marian
core   +4 more sources

Microbial experience through housing in a farmyard-type environment alters intestinal barrier properties in mouse colons

open access: yesScientific Reports, 2023
To close the gap between ultra-hygienic research mouse models and the much more environmentally exposed conditions of humans, we have established a system where laboratory mice are raised under a full set of environmental factors present in a ...
Henriette Arnesen   +7 more
doaj   +1 more source

A Preliminary Study Examining the Binding Capacity of Akkermansia muciniphila and Desulfovibrio spp., to Colonic Mucin in Health and Ulcerative Colitis. [PDF]

open access: yesPLoS ONE, 2015
Akkermansia muciniphila and Desulfovibrio spp. are commensal microbes colonising the mucus gel layer of the colon. Both species have the capacity to utilise colonic mucin as a substrate. A.
Helen Earley   +10 more
doaj   +1 more source

Expression profiling identifies key genes and biological functions associated with eosinophilic esophagitis in human patients

open access: yesFrontiers in Allergy, 2023
IntroductionEosinophilic Esophagitis (EoE) is a chronic allergic disease characterized by progressive inflammation of the esophageal mucosa. This chronic inflammatory disorder affects up to 50 per 100,000 individuals in the United States and Europe yet ...
Holly A. Morrison   +10 more
doaj   +1 more source

Up-regulation of MUC2 and IL-1β expression in human colonic epithelial cells by Shigella and its interaction with mucins. [PDF]

open access: yesPLoS ONE, 2011
BackgroundThe entire gastrointestinal tract is protected by a mucous layer, which contains complex glycoproteins called mucins. MUC2 is one such mucin that protects the colonic mucosa from invading microbes.
Radhakrishnan Prakash   +3 more
doaj   +1 more source

Molecular studies of phages-Klebsiella pneumoniae in mucoid environment: innovative use of mucolytic agents prior to the administration of lytic phages

open access: yesFrontiers in Microbiology, 2023
Mucins are important glycoproteins that form a protective layer throughout the gastrointestinal and respiratory tracts. There is scientific evidence of increase in phage-resistance in the presence of mucin for some bacterial pathogens.
Olga Pacios   +26 more
doaj   +1 more source

Mucin1 and Mucin16: Therapeutic Targets for Cancer Therapy

open access: yesPharmaceuticals, 2021
The mucin (MUC) family is a group of highly glycosylated macromolecules that are abundantly expressed in mammalian epithelial cells. MUC proteins contribute to the formation of the mucus barrier and thus have protective functions against infection ...
Dong-Hee Lee   +3 more
doaj   +1 more source

Stimulation of neutrophil oxidative burst by calcium phosphate particles with adsorbed mucin

open access: yesRussian Open Medical Journal, 2021
Objective — Mucin can promote formation of gallstones via precipitation with calcium phosphate. The proinflammatory effect of mucin-coated particles is still unclear, and our aim was to study the role of mucin sorption in activation of neutrophil ...
Elena V. Mikhalchik   +9 more
doaj   +1 more source

Morphometric analysis and mucin histochemistry of gallbladder surface and glandular epithelium in swine [PDF]

open access: yesBulgarian Journal of Veterinary Medicine, 2020
The aim of the study was to perform morphometric analysis and to distinguish histochemically the variety of mucins in surface and glandular gallbladder epithelium in swine at different ages.
I. S. Stefanov
doaj   +1 more source

Supplementation with sesame oil suppresses genotoxicity, hepatotoxicity and enterotoxicity induced by sodium arsenite in rats

open access: yesLipids in Health and Disease, 2023
Background Sesame oil, an edible essential oil, is known to be rich in unsaturated fatty acids, vitamins and lignans with several reported health-promoting benefits.
Akinleye Stephen Akinrinde   +2 more
doaj   +1 more source

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