Results 71 to 80 of about 29,844,443 (188)

Physical and chemical characteristics of mucin secreted by pseudomyxoma peritonei (PMP)

open access: yes, 2017
Background: Pseudomyxoma peritonei (PMP) is a rare disease with excess intraperitoneal mucin secretion. Treatment involves laparotomy, cytoreduction and chemotherapy that is very invasive with patients often suffers from numerous compromises.
Pillai, K   +4 more
core   +1 more source

Mucin-Like Domain of Mucosal Addressin Cell Adhesion Molecule-1 Facilitates Integrin α4β7-Mediated Cell Adhesion Through Electrostatic Repulsion

open access: yesFrontiers in Cell and Developmental Biology, 2020
The homing of lymphocytes from blood to gut-associated lymphoid tissue is regulated by interaction between integrin α4β7 with mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) expressed on the endothelium of high endothelial venules (HEVs ...
MengYa Yuan   +7 more
doaj   +1 more source

Mucin 1 Oncoprotein Expression Is Suppressed by the miR-125b Oncomir

open access: yesGenes & Cancer, 2010
The MUC1 oncoprotein is overexpressed in most human breast cancers by mechanisms that are incompletely understood. The microRNA, miR-125b, is downregulated in breast cancer cells. The present studies demonstrate that the MUC1 3'UTR contains a site for binding of the miR-125b seed region.
Rajabi, H   +5 more
openaire   +3 more sources

Nitric oxide induces MUC5AC mucin in respiratory epithelial cells through PKC and ERK dependent pathways

open access: yesRespiratory Research, 2007
Background Nitric oxide (NO) is generally increased during inflammatory airway diseases. This increased NO stimulates the secretion of mucin from the goblet cell and submucosal glands but the mechanism is still unknown precisely.
Kim Kwan   +8 more
doaj   +1 more source

Membrane-Tethered Mucin-like Polypeptides Sterically Inhibit Binding and Slow Fusion Kinetics of Influenza A Virus [PDF]

open access: yes, 2019
The mechanism(s) by which cell-tethered mucins modulate infection by Influenza A viruses (IAVs) remains an open question. Mucins form both a protective barrier that can block virus binding and recruit IAVs to bind cells via the sialic ...
Corleone, Delaveris   +4 more
core   +1 more source

Pellicle Modification with Casein and Mucin Does Not Promote In Vitro Bacterial Biofilm Formation. [PDF]

open access: yes, 2020
PURPOSE During biofilm formation, bacterial species do not attach directly onto the enamel surface, but rather onto the salivary pellicle. Salivary pellicle modification with casein and mucin can hinder erosive demineralisation of the enamel, but it ...
Saads Carvalho, Thiago   +5 more
core   +1 more source

Targeted disruption of the murine mucin gene 1 decreases susceptibility to cholesterol gallstone formation1

open access: yesJournal of Lipid Research, 2004
Gallbladder mucins play a critical role in the pathogenesis of cholesterol gallstones because of their ability to bind biliary lipids and accelerate cholesterol crystallization.
Helen H. Wang   +3 more
doaj   +1 more source

MUC20 promotes aggressive phenotypes of epithelial ovarian cancer cells via activation of the integrin beta 1 pathway

open access: yes, 2017
Objective. Mucin (MIX) 20 has recently been implicated to play a role in human carcinogenesis. However, the role of MUC20 in epithelial ovarian cancer (EOC) remains to be elucidated. Methods.
陳啟豪;林鶴雄;黃敏銓;徐明洸   +1 more
core   +1 more source

Leucine increases mucin 2 and occludin production in LS174T cells partially via PI3K-Akt-mTOR pathway

open access: yesAnimal Nutrition, 2016
Mucin 2 and occludin play a crucial role in preserving the intestinal mucosal integrity. However, the role for leucine mediating intestinal mucin 2 and occludin expression has little been investigated.
Xiangbing Mao   +4 more
doaj   +1 more source

Submaxillary Mucin: its Effect on Aroma Release from Acidic Drinks and New Insight into the Effect of Aroma Compounds on its Macromolecular Integrity [PDF]

open access: yes, 2019
Submaxillary mucin is a major component that defines the makeup and functionality of saliva. Understanding its structure and function during food intake is key to designing appropriate strategies for enhancing the delivery of flavour.
Harding, Stephen E.   +16 more
core   +1 more source

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