Results 21 to 30 of about 132,096 (256)

Steroidal but not embryonic regulation of mucin 1 expression in bovine endometrium. [PDF]

J Reprod Dev, 2021
In cow herd management, inadequate embryo implantation leads to pregnancy loss and causes severe economic losses. Thus, it is crucial to understand the molecular mechanisms underlying endometrial receptivity and subsequent embryo implantation. Transmembrane glycocalyx mucin 1 (MUC1) has a large and highly glycosylated extracellular domain known to ...
Kubota K, Miwa M, Hayashi KG, Hosoe M, Sakatani M.   +4 more
europepmc   +5 more sources

Theragnostic perspectives of Mucin 1 for oral cancer

Oral Oncology Reports
Dharmaraj Senthilkumar, Baskar Venkidasamy   +1 more
doaj   +2 more sources

Expression of aberrantly glycosylated Mucin‐1 in ovarian cancer [PDF]

Histopathology, 2010
Van Elssen C H M J, Frings P W H, Bot F J, Van de Vijver K K, Huls M B, Meek B, Hupperets P, Germeraad W T V & Bos G M J
(2010) Histopathology57, 597–606
Expression of aberrantly glycosylated Mucin‐1 in ovarian cancerAims:  Mucin 1 (MUC1) is an important tumour‐associated antigen (TAA), both overexpressed and aberrantly glycosylated in ...
Van Elssen, Catharina H. M. J., Frings, Peter W. H., Bot, Freek J., Van de Vijver, Koen K., Huls, Mariska B., Meek, Bob, Hupperets, Pierre, Germeraad, Wilfred T. V., Bos, Gerard M. J.   +8 more
openaire   +3 more sources

Mucin Level as a Potential Biomarker for Breast Cancer Diagnosis

MCBS (Molecular and Cellular Biomedical Sciences), 2022
Background: Breast cancer is the second leading cause of cancer death and a health problem worldwide. Secreted mucins are upregulated in ductal adenocarcinoma of the breast, however, the use of mucin as breast cancer biomarker has not been established ...
Tagwa Sayed Abdihalim, Alkhair Abd Almahmoud Idris   +1 more
doaj   +1 more source

Transmembrane Mucin 1 Blocks Fluorescein Ingress to Corneal Epithelium. [PDF]

Invest Ophthalmol Vis Sci, 2022
To determine the role of transmembrane mucins in blocking fluorescein ingress to the corneal epithelium and its deficiency in contributing to corneal fluorescein punctate staining.A dry eye model was established by extirpating lacrimal and Harderian glands in rabbits to correlate the expression of mucins with fluorescein-stained areas on the corneal ...
Sun YC, Hung KF, Li TY, Chang YA, Yeh PT, Hu FR.   +5 more
europepmc   +3 more sources

Mouse mucin 1 (MUC1) defined by monoclonal antibodies [PDF]

International Journal of Cancer, 1998
Mucins are highly expressed in many different human cancers and numerous murine monoclonal antibodies (MAbs) to human mucins, particularly Mucin 1 (MUC1), have been produced. However, no such antibodies to murine mucin 1 (muc1) have been described and we now describe 6 different antibodies produced to murine muc1 and to human MUC1 cytoplasmic tail ...
P X, Xing, C, Lees, J, Lodding, J, Prenzoska, G, Poulos, M, Sandrin, S, Gendler, I F, McKenzie   +7 more
openaire   +2 more sources

Mucin 1 Gene (MUC1) and Gastric-Cancer Susceptibility [PDF]

International Journal of Molecular Sciences, 2014
Gastric cancer (GC) is one of the major malignant diseases worldwide, especially in Asia. It is classified into intestinal and diffuse types. While the intestinal-type GC (IGC) is almost certainly caused by Helicobacter pylori (HP) infection, its role in the diffuse-type GC (DGC) appears limited.
Saeki, Norihisa, Sakamoto, Hiromi, Yoshida, Teruhiko   +2 more
openaire   +2 more sources

Mucin 16, the dimerization copycat of mucin 1?

The FASEB Journal, 2021
Mucin 1 (MUC1), a transmembrane mucin that serves a protective role by inhibiting extracellular pathogens from entering epithelial cells is also implicated in forming cancerous cells through dimer formation. Upon expression and localization in the membrane, MUC1 proteins form cysteine‐dependent homodimers through the juxtamembrane domain CQC motif. The
Robert Murphy, Nicole Butch, Edwin Li
openaire   +1 more source

MUCIN 1 in Prostate Cancer

, 2021
ABSTRACT Despite extensive research efforts in prostate cancer for the last several decades, the disease remains a leading cause of cancer death in men in the developed world. A typical feature of prostate cancer initiation and progression is the landscape of genetic alterations, which changes the expression patterns of numerous molecules in prostate ...
Kapoor A, Gu Y, Lin X, Peng J, Major P, Tang D.   +5 more
europepmc   +3 more sources

Pro-Resolving Mediator Annexin A1 Regulates Intracellular Ca2+ and Mucin Secretion in Cultured Goblet Cells Suggesting a New Use in Inflammatory Conjunctival Diseases

Frontiers in Immunology, 2021
The amount of mucin secreted by conjunctival goblet cells is regulated to ensure the optimal level for protection of the ocular surface. Under physiological conditions lipid specialized pro-resolving mediators (SPM) are essential for maintaining tissue ...
Anne V. Lyngstadaas, Anne V. Lyngstadaas, Anne V. Lyngstadaas, Markus V. Olsen, Markus V. Olsen, Markus V. Olsen, Jeffrey A. Bair, Robin R. Hodges, Tor P. Utheim, Tor P. Utheim, Tor P. Utheim, Charles N. Serhan, Darlene A. Dartt   +12 more
doaj   +1 more source