Results 211 to 220 of about 107,445,010 (245)
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CTL in mice immunized with human mucin 1 are MHC-restricted
The Journal of Immunology, 1995Abstract CTLs that recognize tumor Ags have been described in mice and humans, particularly for melanoma. These CTLs are CD8+, which is MHC-restricted. In contrast, in human carcinomas of the breast, pancreas, or ovary, and in multiple myeloma, CD8+ CTLs have been described that lyse targets expressing human MUC1 in a non-MHC ...
V, Apostolopoulos +3 more
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Mucin-1-related T cell infiltration in colorectal carcinoma
Cancer Immunology, Immunotherapy, 1996Mucins (MUC) are highly glycosylated molecules widely expressed on epithelia of different origins, including colonic mucosa. Altered glycosylation processes in tumour cells result in the exposure of normally cryptic peptide epitopes, which may then be recognized as tumour-specific antigens.
Mulder, W. M.C. +5 more
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Designer Tridentate Mucin 1 Aptamer for Targeted Drug Delivery
Journal of Pharmaceutical Sciences, 2012A single-stranded DNA aptamer (APT) capable of targeting mucin 1 (MUC1) extracellular protein was modified to increase its drug delivery specificity toward MUC1 overexpressing cancer cell line, MCF7. The active targeting region of APT was truncated and variable repeats (one, two, or three) of this sequence were synthesized. An aptamer formed from three
Tan, L. +4 more
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Purified mucins in drug delivery research
Advanced Drug Delivery Reviews, 2021Matthias Marczynski +2 more
exaly
Identification of Allobaculum mucolyticum as a novel human intestinal mucin degrader
Gut Microbes, 2021Guus H van Muijlwijk +2 more
exaly
The effects of diet and gut microbiota on the regulation of intestinal mucin glycosylation
Carbohydrate Polymers, 2021Meiyi Zhang, Fengwei Tian, Gang Wang
exaly