Results 161 to 170 of about 111,910 (294)

Breaking Alzheimer's Disease Barrier: The Role of Xanthoceras sorbifolia Bunge Oil in Gut‐Brain Axis and TLR4/Myd88/MAPK Pathway Inhibition

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with cognitive decline and neuroinflammation. Xanthoceras sorbifolia Bunge oil (XSBO), a woody plant oil rich in bioactive fatty acids, has shown potential health benefits.
Lijing Du   +8 more
wiley   +1 more source

Incidental High-Grade Appendiceal Mucinous Neoplasm. [PDF]

open access: yesCRSLS
Fatah FH   +6 more
europepmc   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

open access: yesSmart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou   +4 more
wiley   +1 more source

Gut microbiota dysbiosis in the inflammatory pathogenesis of diabetic retinopathy

open access: yesVIEW, EarlyView.
This graphical abstract illustrates how gut dysbiosis drives diabetic retinopathy through the gut‐retina axis, a process unfolding in three interconnected stages. First, in the gut, a decrease in beneficial bacteria and an increase in pro‐inflammatory taxa compromise the intestinal barrier, causing a “leaky gut” that allows LPS to translocate into the ...
Junyan Hu, Jingxiang Zhong
wiley   +1 more source

A Giant 25cm Hepatobiliary Mucinous Cystic Neoplasm Mimicking Hydatid Disease- A Diagnostic Pitfall with Radiological Water-Lily Sign: A Case Report with Literature Review

open access: yesInternational Journal of Medical Students
Background Hepatobiliary mucinous cystic neoplasm is a rare type of liver tumor that primarily occurs in middle-aged women. Their radiological appearance can mimic that of parasitic liver disease, which can be a major challenge.
Sheeza Ahmed   +9 more
doaj  

Silent Sinus Syndrome: 13‐Year Experience With Endoscopic Surgery and Long‐Term Patient Outcomes

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Silent sinus syndrome (SSS) is a rare condition characterized by spontaneous maxillary sinus collapse with associated orbital deformity. Existing studies are limited by heterogeneous surgical approaches, small sample sizes, and short follow‐up.
Sholem Hack   +3 more
wiley   +1 more source

Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas   +3 more
wiley   +1 more source

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