Conversion of sustained release omeprazole loaded buccal films into fast dissolving strips using supercritical carbon dioxide (scCO2) processing, for potential paediatric drug delivery [PDF]
This study involves the development of thin oral solvent cast films for the potential delivery of the proton pump inhibitor, omeprazole (OME) via the buccal mucosa for paediatric patients.
Boateng, Joshua S. +3 more
core +1 more source
Composite bi-layered erodible films for potential ocular drug delivery [PDF]
Bi-layered hydroxypropylmethylcellulose and Eudragit based films were formulated as potential ocular drug delivery systems using chloramphenicol as a model antibiotic.
A.M. Popescu +37 more
core +1 more source
A Window for Enhanced Oral Delivery of Therapeutics via Lipid Nanoparticles
Hilda Amekyeh,1 Rayan Sabra,2 Nashiru Billa3 1Department of Pharmaceutics, School of Pharmacy, University of Health and Allied Sciences, Ho, Ghana; 2Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT, USA; 3College of Pharmacy ...
Amekyeh H, Sabra R, Billa N
doaj
Influence of excipients on spray-dried powders for inhalation [PDF]
Two areas attracting considerable attention when developing effective pulmonary drug delivery systems include the improvement of aerosolisation efficiency of the inhaled formulation and the controlled release of drug from the formulation following ...
Adi +45 more
core +1 more source
Ocular pharmacoscintigraphic and aqueous humoral drug availability of ganciclovir-loaded mucoadhesive nanoparticles in rabbits [PDF]
The present report describes the improved ocular retention and aqueous humoral drug availability of ganciclovir (GCV) when administered via topical instillation of different kind of nanoparticles onto the rabbit eye.
Ahmad, Farjam Jalees +6 more
core +2 more sources
Initially, chemotherapy is effective for treatment of bladder cancer after transurethral resection of the bladder. However, certain patients progressively become unresponsive after multiple treatment cycles, which results from the rapid and almost ...
Hui Guo +7 more
doaj +1 more source
Chitosan/poly(lactic-co-glycolic)acid Nanoparticle Formulations with Finely-Tuned Size Distributions for Enhanced Mucoadhesion [PDF]
Feipeng Yang +3 more
openalex +1 more source
Mucoadhesion is defined as the adhesion between a mucosal surface and, natural or synthetic, macromolecules. Mucoadhesion is a complex mechanism and it depends intermolecular interactions. The adhesive macromolecules can be part of a pharmaceutical formulation, turning it in a mucoadhesive preparation as well. The mucoadhesion mechanism is divided into
openaire +1 more source
Pullulan-Based Spray-Dried Mucoadhesive Microparticles for Sustained Oromucosal Drug Delivery
Mucoadhesive microparticles for oromucosal drug delivery offer several advantages, including intimate contact with the mucosa, delivery to less accessible regions, extended residence time, sustained drug release, reduced irritation, and improved patient ...
Ting Liu +4 more
doaj +1 more source

