Results 41 to 50 of about 3,483 (174)

Health Screening and Post‐Arrival Services for Refugee Children From Afghanistan

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim To examine refugee health screening and services for Afghan children in the unique context of emergency expedited humanitarian resettlement in Melbourne, Australia. Methods Retrospective audit of Afghan children who attended a specialist child refugee health service between August 2021–April 2024. Results Participants included 218 children
Amy Williamson, Eva Sudbury, Rija Khanal, Jade Woon, Jennifer Schaefer, Georgia Paxton   +5 more
wiley   +1 more source

Clinical and Radiological Features Suggestive of Mucopolysaccharidosis in Two Siblings From Sudan: A Case Series

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Mucopolysaccharidosis should be suspected in patients presenting with multisystem involvement, including coarse facial features, skeletal abnormalities, and progressive organ dysfunction, particularly in resource‐limited settings where delayed diagnosis is common.
Alaa Bella, Mumen Abdalazim Dafallah, Ashraf Yousif Fadlalla, Bothaina Faisal Elmardi, Yomna Mohialdin Alataya, Abdalla Abdelmahmoud Abdalla, Mohammed Almeldin Ahmed Ibrahim, Mawada Faisal Nugud, Salah Elamin Ahmed Babiker, Hiba faroug Al_amin, Safaa Ayoub Yousif Mohammed, Moawia Elbalal Mohammed   +11 more
wiley   +1 more source

Cardiac Involvement in Pediatric Mucopolysaccharidoses Patients and their Genetic Profile: A Retrospective Single-center Study

Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging
Background: Mucopolysaccharidoses (MPS) are rare metabolic disorders of monogenic inheritance, with varying degrees of cardiac involvement due to undegraded glycosaminoglycans getting aggregated in the spongiosa of the cardiac valves, the myocardium, and
Shruti Irene Varghese, Joshua Abishek Christudoss, Rekha Aaron, Sumita Danda, Jesu Krupa   +4 more
doaj   +1 more source

High‐Power Surgical Laser for Treatment of Oral Manifestations of Mucopolysaccharidosis VI: A Case Report

Special Care in Dentistry, Volume 46, Issue 4, July/August 2026.
ABSTRACT Mucopolysaccharidosis type VI (MPS VI), a rare metabolic disorder, results from glycosaminoglycan accumulation in tissues, frequently leading to hyperplastic gingival alterations that necessitate comprehensive intervention. An 11‐year‐old male patient diagnosed with MPS VI required hospitalization due to complications associated with a ...
Regina Maria Raffaele, Mario Eduardo Baldo, Bianca Ribeiro Marques, Stefan Gabriel Gonçalves Martiniano, Gleyson Kleber do Amaral Silva, Rafael Ferreira   +5 more
wiley   +1 more source

Leukocyte Imbalances in Mucopolysaccharidoses Patients

Biomedicines, 2023
Mucopolysaccharidoses (MPSs) are rare inherited lysosomal storage diseases (LSDs) caused by deficient activity in one of the enzymes responsible for glycosaminoglycans lysosomal degradation.
Nuno Lopes, Maria L. Maia, Cátia S. Pereira, Inês Mondragão-Rodrigues, Esmeralda Martins, Rosa Ribeiro, Ana Gaspar, Patrício Aguiar, Paula Garcia, Maria Teresa Cardoso, Esmeralda Rodrigues, Elisa Leão-Teles, Roberto Giugliani, Maria F. Coutinho, Sandra Alves, M. Fátima Macedo   +15 more
doaj   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

Prenatal Diagnosis, Volume 46, Issue 5-6, Page 623-635, May 2026.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear, Beltran Borges, Billie R. Lianoglou, Tony Lum, Emma Canepa, Jennifer L. Cohen, Julia E. H. Brown, Akos Herzeg   +7 more
wiley   +1 more source

Structure and functions of Glycosaminoglycans: a short review (with some personal scientific contributions)

Atti della Accademia Peloritana dei Pericolanti - Classe di Scienze Medico-Biologiche, 2020
This present article wishes to underline the strong contribution to both structure and functions of living bodies of a group of acidic polysaccharides, the Glycosaminoglycans (GAGs), usually covalently linked to proteins to give Proteoglycans (PGs): GAGs
Alberto Calatroni
doaj   +1 more source

Multiorgan Molecular Landscape of Severe COVID‐19 Revealed by Consensus Gene Signatures and RAB8B Targeting

Journal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Severe COVID‐19 involves hyperinflammation and multiorgan pathology, but consistent gene signatures remain elusive. We aimed to identify consensus transcriptomic signatures and molecular mechanisms in severe COVID‐19. We performed an integrative analysis of 39 studies spanning 11 tissue types, 1551 bulk RNA‐seq samples, and over 2 million ...
Jonathan Peña Avila, Peter Park, Youvika Singh, Paulo P. Amaral, Ícaro Castro, Felipe Ten‐Caten, Viviane Schuch, André N. A. Gonçalves, Jeevan Giddaluru, Mauro César Cafundó Morais, Rodrigo L. T. Ogava, Thiago Lubiana, Gabriel Amoroso de Castro, Rodrigo Aquino, Luiz Durão, Júlia Raspante Martins, Leandro Jimenez, André G. Costa‐Martins, Patrícia Gonzalez‐Dias, Thiago Dominguez Crespo Hirata, Thomaz Lüscher Dias, Débora Guerra Peixe, Adriana Simizo, Juan Carlo Santos e Silva, Amanda Pereira Vasconcelos, Marcelo Berçot Rodrigues, Bianca G. Castelucci, João Victor Virgillio‐da‐Silva, Larissa Menezes, Pedro M. Moraes‐Vieira, Otavio Cabral‐Marques, Helder I. Nakaya   +31 more
wiley   +1 more source

Racial and Ethnic Disparities in Care for Pediatric Sleep‐Disordered Breathing

OTO Open, Volume 10, Issue 2, April-June 2026.
Abstract Objective Obstructive sleep disordered breathing is the most common indication for pediatric tonsillectomy in the United States, but there are barriers to specialty care that may contribute to disparities in tonsillectomy use. This study examined the association between race, ethnicity, urban/rural residence, and other factors in access to ...
Colleen C. McLaughlin, Jesse L. Hawke, Emily F. Boss, Guy M. Brock, Meredith M. Lind, Tasleem J. Padamsee, Prasanth Pattisapu, Deena J. Chisolm, Laura J. Chavez   +8 more
wiley   +1 more source

Hematopoietic stem cell transplantation in pediatric patients with type VI mucopolysaccharidosis [PDF]

Clinical and Experimental Pediatrics
Background It is uncertain whether hematopoietic stem cell transplantation (HSCT), versus standard enzyme replacement therapy (ERT), is effective for type VI mucopolysaccharidosis (MPS VI).
Vedat Uygun, Koray Yalçın, Hayriye Daloğlu, Seda Öztürkmen, Suna Çelen, Suleimen Zhumatayev, Gülsün Karasu, Akif Yeşilipek   +7 more
doaj   +1 more source