Results 161 to 170 of about 10,557 (200)

Genetic Modification of Mucor circinelloides to Construct Stearidonic Acid Producing Cell Factory

open access: yesInternational Journal of Molecular Sciences, 2019
Stearidonic acid (SDA; 18:4, n-3) is the delta 15-desaturase product of gamma linolenic acid (GLA; 18:3, n-6) and delta 6-desaturase product of alpha linolenic acid (ALA; 18:3, n-3).
Victoriano Garre   +2 more
exaly   +2 more sources
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Metabolic Engineering of Mucor circinelloides for Zeaxanthin Production

2012
Mucor circinelloides is a β-carotene producing zygomycete amenable to metabolic engineering using molecular tools. The crtS gene of the heterobasidiomycetous yeast Xanthophyllomyces dendrorhous encodes the enzymatic activities β-carotene hydroxylase and ketolase, allowing this yeast to produce the xanthophyll called astaxanthin.
Marta, Rodríguez-Sáiz   +2 more
openaire   +2 more sources

Integrative transformation by homologous recombination in the zygomycete Mucor circinelloides

Molecular and General Genetics MGG, 1991
Transformation of a Mucor circinelloides Leu- strain with the plasmid pAD45, harbouring the wild-type allele (leuA+) and a chymosin gene, led to the identification of mitotically stable transformants after one to three vegetative growth cycles on non-selective medium.
J, Arnau, L P, Jepsen, P, Strøman
openaire   +2 more sources

Molecular Detection of Mucor Circinelloides in Diabetic Patients

Pakistan Journal of Medical and Health Sciences, 2022
Workload Aims: This study was aimed to detect of Mucor circinelloides in diabetic patients and compare between the cultural and molecular methods for rapid and efficiency detection Materials and Methods: A total of one hundred specimens were collected from patients with diabetes mellitus who attended medical city in Baghdad for a period of four ...
Abbas M. Ammari   +2 more
openaire   +1 more source

A negative regulator of light-inducible carotenogenesis in Mucor circinelloides

Molecular Genetics and Genomics, 2001
Mucor circinelloides responds to blue light by activating carotene biosynthesis. Wild-type strains grown in darkness contain minimal amounts of beta-carotene because of the low levels of transcription of the structural genes for carotenogenesis. When exposed to a light pulse, the level of transcription of these genes increases strongly, leading to the ...
E, Navarro   +6 more
openaire   +2 more sources

Sporulation on blood serum increases the virulence of Mucor circinelloides

Microbial Pathogenesis, 2019
Mucor circinelloides is an opportunistic human pathogen that is used to study mucormycosis, a rare but lethal infection in susceptible immunosuppressed patients. However, the virulence characteristics of this pathogen have not been fully elucidated.
J Alberto, Patiño-Medina   +9 more
openaire   +2 more sources

Gene replacement and ectopic integration in the zygomycete Mucor circinelloides

Current Genetics, 1993
Transformation of Mucor circinelloides with plasmid pTL42 led to the identification of different integrative events. Analysis of eight transformed strains allowed the detection of three classes of transformants: integrative types derived from either homologous (exclusively at the leuA locus) or heterologous recombination and a class which originated by
J, Arnau, P, Strøman
openaire   +2 more sources

Primary cutaneous zygomycosis due to Mucor circinelloides

Australasian Journal of Dermatology, 2002
SUMMARYA 62‐year‐old woman with myelodysplastic syndrome presented with a 4‐week history of a large indurated ulcer with a black eschar on the forearm following trauma. On biopsy a diagnosis of zygomycosis was made as broad, sparsely septate, thin‐walled hyphae were seen in the deep dermis and subcutaneous fat.
Suresh, Chandra, Alan, Woodgyer
openaire   +2 more sources

Mutants of the Carotenoid Biosynthetic Pathway of Mucor circinelloides

Experimental Mycology, 1995
Abstract Navarro, E., Sandmann, G., and Torres-Martinez, S. 1995. Mutants of the carotenoid biosynthetic pathway of Mucor circinelloides. Experimental Mycology 19, 186-190. We have isolated and characterized a number of mutants affected in the biosynthesis of β-carotene in the fungus Mucor circinelloides.
Eusebio Navarro   +2 more
openaire   +1 more source

Molecular Tools for Carotenogenesis Analysis in the Zygomycete Mucor circinelloides

2012
The carotene producer fungus Mucor circinelloides is the zygomycete more amenable to genetic manipulations by using molecular tools. Since the initial development of an effective procedure of genetic transformation, more than two decades ago, the availability of new molecular approaches such as gene replacement techniques and gene expression ...
Santiago, Torres-Martínez   +5 more
openaire   +2 more sources

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