Results 1 to 10 of about 1,939,990 (302)

Enhancing microalgal lipid accumulation for biofuel production

open access: yesFrontiers in Microbiology, 2022
Microalgae have high lipid accumulation capacity, high growth rate and high photosynthetic efficiency which are considered as one of the most promising alternative sustainable feedstocks for producing lipid-based biofuels.
Zhi Zhu   +7 more
doaj   +5 more sources

Lipid Accumulation and Chronic Kidney Disease [PDF]

open access: yesNutrients, 2019
Obesity and hyperlipidemia are the most prevalent independent risk factors of chronic kidney disease (CKD), suggesting that lipid accumulation in the renal parenchyma is detrimental to renal function. Non-esterified fatty acids (also known as free fatty acids, FFA) are especially harmful to the kidneys. A concerted, increased FFA uptake due to high fat
Zhenguo Wang   +2 more
exaly   +5 more sources

Tumour-driven lipid accumulation in oenocytes reflects systemic lipid alterations. [PDF]

open access: yesPLoS Genetics
Cancer cachexia is a multifactorial syndrome characterized by systemic metabolic dysfunction, including liver steatosis. In this study, we examined the role of larval oenocytes - hepatocyte-like cells, in a Drosophila model of cancer cachexia.
Chang Liu   +4 more
doaj   +2 more sources

Lutein Attenuates Lipid Accumulation in Association with TFEB Nuclear Translocation and Autophagy–Lysosomal Responses in a Cellular Model of Hepatic Steatosis [PDF]

open access: yesAntioxidants
Lutein is a dietary xanthophyll carotenoid valued for its antioxidant properties that has been shown to benefit liver health and reduce hepatic lipid accumulation; however, this lipid-lowering effect cannot be fully attributed to its antioxidant activity,
Faride Saud   +6 more
doaj   +2 more sources

Oxysterol undersulfation promotes osteoarthritis by fueling chondrocyte lipid accumulation [PDF]

open access: yesNature Communications
Osteoarthritis (OA) is a common degenerative joint disease with no curative treatments and a poorly understood etiology. Here, we report that defective sulfation, a largely underexplored chemical modification of lipid metabolites, drives pathogenic lipid
Huanbo Wang   +17 more
doaj   +2 more sources

The effect of chitooligosaccharides on oleic acid-induced lipid accumulation in HepG2 cells

open access: yesSaudi Pharmaceutical Journal, 2016
This experiment aimed to evaluate the capacities of two types of chitooligosaccharides (COS) with different molecular weights for the ability to eliminate lipid accumulation in hepatocytes.
Peiqiu Cao   +4 more
doaj   +3 more sources

Astrocytes in stress accumulate lipid droplets [PDF]

open access: yesGlia, 2021
AbstractWhen the brain is in a pathological state, the content of lipid droplets (LDs), the lipid storage organelles, is increased, particularly in glial cells, but rarely in neurons. The biology and mechanisms leading to LD accumulation in astrocytes, glial cells with key homeostatic functions, are poorly understood.
Tina Smolič   +11 more
openaire   +2 more sources

Lipid metabolism and accumulation in oilseed crops [PDF]

open access: yesOCL, 2021
Triacylglycerols (TAGs) serve as the most important storage form of energy and carbon in eukaryotic cells and thus are one of the fundamental macronutrients for animal and human diet. They are also used as a major feedstock for diverse industrial and energetic sectors due to their high energy density. Oilseed crops represent the most valuable source of
Miklaszewska, Magdalena   +3 more
openaire   +4 more sources

Swertia mussotii prevents high-fat diet-induced non-alcoholic fatty liver disease in rats by inhibiting expression the TLR4/MyD88 and the phosphorylation of NF-κB

open access: yesPharmaceutical Biology, 2022
Context Swertia mussotii Franch. (Gentianaceae) is a source of the traditional Tibetan medicine, ZangYinChen, and is used to treat chronic hepatitis and many types of jaundice.Objective This study explored the therapeutic effects and mechanism of S ...
Ming Dong Si   +8 more
doaj   +1 more source

ACSM5 inhibits ligamentum flavum hypertrophy by regulating lipid accumulation mediated by FABP4/PPAR signaling pathway

open access: yesBiology Direct, 2023
Background Ligamentum flavum (LF) hypertrophy is the main cause of lumbar spinal canal stenosis (LSCS). Previous studies have shown that LF hypertrophy tissue exhibits abnormal lipid accumulation, but the regulatory mechanism remains unclear.
Yanlin Cao   +4 more
doaj   +1 more source

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