Results 1 to 10 of about 3,316,815 (349)

Enhancing microalgal lipid accumulation for biofuel production

open access: yesFrontiers in Microbiology, 2022
Microalgae have high lipid accumulation capacity, high growth rate and high photosynthetic efficiency which are considered as one of the most promising alternative sustainable feedstocks for producing lipid-based biofuels.
Zhi Zhu   +7 more
doaj   +4 more sources

Vicious cycle of lipid peroxidation and iron accumulation in neurodegeneration

open access: yesNeural Regeneration Research, 2023
Lipid peroxidation and iron accumulation are closely associated with neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, and Huntington’s diseases, or neurodegeneration with brain iron accumulation disorders.
Irene Villalón-García   +10 more
doaj   +2 more sources

Swertia mussotii prevents high-fat diet-induced non-alcoholic fatty liver disease in rats by inhibiting expression the TLR4/MyD88 and the phosphorylation of NF-κB

open access: yesPharmaceutical Biology, 2022
Context Swertia mussotii Franch. (Gentianaceae) is a source of the traditional Tibetan medicine, ZangYinChen, and is used to treat chronic hepatitis and many types of jaundice.Objective This study explored the therapeutic effects and mechanism of S ...
Ming Dong Si   +8 more
doaj   +1 more source

How does hepatic lipid accumulation lead to lipotoxicity in non-alcoholic fatty liver disease?

open access: yesHepatology International, 2021
Non-alcoholic fatty liver disease (NAFLD), characterized as excess lipid accumulation in the liver which is not due to alcohol use, has emerged as one of the major health problems around the world.
Yana Geng   +4 more
semanticscholar   +1 more source

Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy

open access: yesDiabetes, 2023
Ectopic lipid accumulation in renal tubules is closely related to the pathogenesis of diabetic kidney disease (DKD), and mitochondrial dysfunction is thought to play a key role in lipid accumulation. Therefore, maintaining mitochondrial homeostasis holds
Yuxia Zhou   +18 more
semanticscholar   +1 more source

ACSM5 inhibits ligamentum flavum hypertrophy by regulating lipid accumulation mediated by FABP4/PPAR signaling pathway

open access: yesBiology Direct, 2023
Background Ligamentum flavum (LF) hypertrophy is the main cause of lumbar spinal canal stenosis (LSCS). Previous studies have shown that LF hypertrophy tissue exhibits abnormal lipid accumulation, but the regulatory mechanism remains unclear.
Yanlin Cao   +4 more
doaj   +1 more source

Role of Lipid Accumulation and Inflammation in Atherosclerosis: Focus on Molecular and Cellular Mechanisms

open access: yesFrontiers in Cardiovascular Medicine, 2021
Atherosclerosis is a chronic lipid-driven and maladaptive inflammatory disease of arterial intima. It is characterized by the dysfunction of lipid homeostasis and signaling pathways that control the inflammation.
Khojasteh Malekmohammad   +2 more
semanticscholar   +1 more source

Lipid Accumulation Induced by APOE4 Impairs Microglial Surveillance of Neuronal-Network Activity

open access: yesbioRxiv, 2022
Apolipoprotein E4 (APOE4) is the greatest known genetic risk factor for developing late- onset Alzheimer’s disease and its expression in microglia is associated with pro- inflammatory states.
Matheus B. Victor   +15 more
semanticscholar   +1 more source

Puerarin Prevents Bisphenol S Induced Lipid Accumulation by Reducing Liver Lipid Synthesis and Promoting Lipid Metabolism in C57BL/6J Mice

open access: yesToxics, 2023
Bisphenol S (BPS) is an environmental pollutant that can accumulate in the human body and cause harm. Puerarin (PUE) is a flavonoid with anti-inflammatory and antioxidant effects.
Zi-Yao Wu   +6 more
doaj   +1 more source

Selenium reduces hepatopancreas lipid accumulation of grass carp (Ctenopharyngodon idella) fed high-fat diet via lipophagy activation

open access: yesAnimal Nutrition, 2023
It has been reported that selenium (Se) can reduce hepatopancreas lipid accumulation induced by high-fat diet. However, its mechanism is still unknown.
Xiaotian Zhang   +6 more
doaj   +1 more source

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