Results 11 to 20 of about 1,939,990 (302)
Vicious cycle of lipid peroxidation and iron accumulation in neurodegeneration
Neural Regeneration Research, 2023 Lipid peroxidation and iron accumulation are closely associated with neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, and Huntington’s diseases, or neurodegeneration with brain iron accumulation disorders.
Irene Villalón-García +10 more
doaj +1 more source
Toxics, 2023 Bisphenol S (BPS) is an environmental pollutant that can accumulate in the human body and cause harm. Puerarin (PUE) is a flavonoid with anti-inflammatory and antioxidant effects.
Zi-Yao Wu +6 more
doaj +1 more source
Lipid accumulation and oxidation in glioblastoma multiforme [PDF]
Scientific Reports, 2019 AbstractGlioblastoma multiforme (GBM) is the most common and lethal primary malignant brain tumor in adults. Despite the multimodal standard treatments for GBM, the median survival is still about one year. Analysis of brain tissues from GBM patients shows that lipid droplets are highly enriched in tumor tissues while undetectable in normal brain ...
Bouchra Taïb +6 more
openaire +2 more sources
THE SOURCE OF LIPID ACCUMULATION IN L CELLS [PDF]
The Journal of Cell Biology, 1961 Strain L cells accumulate lipid, concurrent with cessation of protein synthesis, in the stationary phase of growth from the extracellular medium and as a result of de novo synthesis. Cells which have been more severely damaged with an amino acid analogue also accumulate lipid from the extracellular medium, but synthesize very little lipid from labeled ...
K G, Bensch, D W, King, E L, Socolow
openaire +2 more sources
Animal Nutrition, 2023 It has been reported that selenium (Se) can reduce hepatopancreas lipid accumulation induced by high-fat diet. However, its mechanism is still unknown.
Xiaotian Zhang +6 more
doaj +1 more source
The accumulation of bactericidal lipids in staphylococcal abscesses [PDF]
Journal of Medical Microbiology, 1992 Abscesses were generated in the peritoneal cavity of mice by the inoculation of 10(9) staphylococci. Abscess weight increased rapidly, reaching about 200 mg by the fourth day; for the next 60 days, abscess weight increased only slightly. The amount of total lipid increased during abscess development, attaining a peak level of about 19 mg per abscess at
T R, Shryock, E S, Dye, F A, Kapral
openaire +2 more sources
Chloroquine-Induced Accumulation of Autophagosomes and Lipids in the Endothelium [PDF]
International Journal of Molecular Sciences, 2021 Chloroquine (CQ) is an antimalarial drug known to inhibit autophagy flux by impairing autophagosome–lysosome fusion. We hypothesized that autophagy flux altered by CQ has a considerable influence on the lipid composition of endothelial cells. Thus, we investigated endothelial responses induced by CQ on human microvascular endothelial cells (HMEC-1 ...
Ewelina Bik +5 more
openaire +3 more sources
Cell Reports, 2020 Summary: Obesity leads to a state of chronic, low-grade inflammation that features the accumulation of lipid-laden macrophages in adipose tissue. Here, we determined the role of macrophage lipid-droplet accumulation in the development of obesity-induced ...
Xanthe A.M.H. van Dierendonck +9 more
doaj +1 more source
Comparative proteomics profile of lipid-cumulating oleaginous yeast: an iTRAQ-coupled 2-D LC-MS/MS analysis. [PDF]
PLoS ONE, 2013 Accumulation of intracellular lipid in oleaginous yeast cells has been studied for providing an alternative supply for energy, biofuel. Numerous studies have been conducted on increasing lipid content in oleaginous yeasts.
Jiahua Shi +3 more
doaj +1 more source
BRAF Modulates Lipid Use and Accumulation
Cancers, 2022 There is increasing evidence that oxidative metabolism and fatty acids play an important role in BRAF-driven tumorigenesis, yet the effect of BRAF mutation and expression on metabolism is poorly understood. We examined how BRAF mutation and expression modulates metabolite abundance.
Jacqueline A. Turner +12 more
openaire +2 more sources