Results 31 to 40 of about 2,038,928 (302)
Lipid Droplet Accumulation Promotes RPE Dysfunction [PDF]
International Journal of Molecular Sciences, 2022 Non-exudative age-related macular degeneration (AMD) is an irreversibly progressive retinal degenerative disease characterized by dysfunction and loss of retinal pigment epithelium (RPE). It has been suggested that impaired phagocytosis of the RPE is involved in the progression of non-exudative AMD, but the mechanism is not fully clear.
Tomohiro Yako +4 more
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Effect of FTY720P on lipid accumulation in HEPG2 cells [PDF]
, 2023 Nonalcoholic fatty liver disease (NAFLD) is characterized by an increase in hepatic lipid accumulation due to impaired lipid metabolism. Although a correlation was found between NAFLD and sphingosine-1-phosphate (S1P), the role of the sphingolipid ...
Kreydiyyeh, Sawsan Ibrahim, Rida, Reem
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Frontiers in Endocrinology, 2023 AimConfirm and compare the degree of associations of non-traditional lipid profiles and metabolic syndrome (MetS) in Chinese adolescents, determine the lipid parameter with better predictive potential, and investigate their discriminatory power on MetS ...
Zi-yi Chen +6 more
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Naringenin inhibits lipid accumulation by activating the AMPK pathway in vivo and vitro
Food Science and Human Wellness, 2023 The aim of this study was to explore the lipid-lowering effect of naringenin and the underlying mechanism in high-fat-diet-fed SD rats and 3T3-L1 cells. In this study, SD rats were divided into the normal chow diet group (NCD), high fat diet group (HFD),
Xiaoyu Cai +7 more
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The Peroxisome Proliferator-activated Receptor γ (PPARγ) Controls Natural Protective Mechanisms against Lipid Peroxidation in Amyotrophic Lateral Sclerosis [PDF]
, 2012 Recent evidence highlights the peroxisome proliferator-activated receptors (PPARs) as critical neuroprotective factors in several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). To gain new mechanistic insights into the role of
Maggi, Adriana +8 more
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Calcium Affects Polyphosphate and Lipid Accumulation in Mucoromycota Fungi. Dataset
, 2022 Dataset: Calcium Affects Polyphosphate and Lipid Accumulation in Mucoromycota ...
Horn, Svein Jarle +13 more
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The Genetic Basis of Natural Variation in Algal Neutral Lipid Accumulation [PDF]
, 2021 Neutral lipids are known to be involved in an algal adaptation to cold, light, and nutrient stress, but the extent of intraspecific variation and the mechanisms maintaining the variation in this economically important trait are unclear.
Chen, Wen
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Journal of Lipid Research, 1998 Synthesis and accumulation of the recently identified prostaglandin F2α receptor regulatory protein (FPRP) was found to correlate closely with lipid droplet accumulation by 3T3-L1 preadipose cells.
D.J. Orlicky +3 more
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Myocardial Lipid Accumulation in the Diabetic Heart [PDF]
Circulation, 2007 The prevalence of type 2 diabetes mellitus is rising in the United States, with a recent estimate suggesting that 7% of the US population (or 21 million persons) have the disease.1 In addition to well-recognized contributions to coronary artery disease risk, the metabolic derangement of diabetes also can result in abnormalities of cardiac function ...
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Secondary lipid accumulation in lysosomal disease
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2009 Lysosomal diseases are inherited metabolic disorders caused by defects in a wide spectrum of lysosomal and a few non-lysosomal proteins. In most cases a single type of primary storage material is identified, which has been used to name and classify the disorders: hence the terms sphingolipidoses, gangliosidoses, mucopolysaccharidoses, glycoproteinoses,
Walkley, Steven U., Vanier, Marie T.
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