Results 31 to 40 of about 1,939,990 (302)

The Peroxisome Proliferator-activated Receptor γ (PPARγ) Controls Natural Protective Mechanisms against Lipid Peroxidation in Amyotrophic Lateral Sclerosis [PDF]

, 2012
Recent evidence highlights the peroxisome proliferator-activated receptors (PPARs) as critical neuroprotective factors in several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). To gain new mechanistic insights into the role of
Maggi, Adriana, L. Brambilla, Benedusi, Valeria, Brambilla, Liliana, A. Maggi, V. Benedusi, Martorana, Francesca, F. Martorana, Rossi, Daniela   +8 more
core   +1 more source

Lipid accumulation product is a better predictor of metabolic syndrome in Chinese adolescents: a cross-sectional study

Frontiers in Endocrinology, 2023
AimConfirm and compare the degree of associations of non-traditional lipid profiles and metabolic syndrome (MetS) in Chinese adolescents, determine the lipid parameter with better predictive potential, and investigate their discriminatory power on MetS ...
Zi-yi Chen, Lei Liu, Xu-xiu Zhuang, Yi-cong Zhang, Ya-nan Ma, Yang Liu, De-liang Wen   +6 more
doaj   +1 more source

Synthesis and accumulation of a receptor regulatory protein associated with lipid droplet accumulation in 3T3-L1 cells

Journal of Lipid Research, 1998
Synthesis and accumulation of the recently identified prostaglandin F2α receptor regulatory protein (FPRP) was found to correlate closely with lipid droplet accumulation by 3T3-L1 preadipose cells.
D.J. Orlicky, J.G. Lieber, C.L. Morin, R.M. Evans   +3 more
doaj   +1 more source

Naringenin inhibits lipid accumulation by activating the AMPK pathway in vivo and vitro

Food Science and Human Wellness, 2023
The aim of this study was to explore the lipid-lowering effect of naringenin and the underlying mechanism in high-fat-diet-fed SD rats and 3T3-L1 cells. In this study, SD rats were divided into the normal chow diet group (NCD), high fat diet group (HFD),
Xiaoyu Cai, Songxue Wang, Huali Wang, Suwen Liu, Guishan Liu, Huibin Chen, Ji Kang, Hao Wang   +7 more
doaj   +1 more source

results in increased lipid accumulation in vegetative tissue [PDF]

, 2020
Alfalfa (Medicago sativa L.), is the most widely grown perennial forage crop, which is a close relative of the model diploid legume Medicago truncatula.
Stacy D. Singer, Singh, S., Guanqun Chen, James R. Petrie, Peter J. Eastmond, Surinder Singh, Petrie, J. R., Surya N. Acharya, Weselake, R. J., Acharya, S. N., Champa Wijekoon, Eastmond, P. J., Chen, G., Wijekoon, C., Singer, S. D., Randall J. Weselake   +15 more
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Growth kinetics and lipid accumulation in Rhodosporidium toruloides [PDF]

, 2010
The current interest in oleaginous yeasts as a viable source for microbial oil production has led to increasing research in understanding the growth conditions and kinetics of oleaginous yeasts with the aim to optimise productivity. Microbial oils can be
Trzcinski, Antoine
core   +1 more source

Myocardial Lipid Accumulation in the Diabetic Heart [PDF]

Circulation, 2007
The prevalence of type 2 diabetes mellitus is rising in the United States, with a recent estimate suggesting that 7% of the US population (or 21 million persons) have the disease.1 In addition to well-recognized contributions to coronary artery disease risk, the metabolic derangement of diabetes also can result in abnormalities of cardiac function ...
openaire   +2 more sources

Using lipidomics to reveal details of lipid accumulation in developing seeds from oilseed rape (Brassica napus L.) [PDF]

, 2018
With dwindling available agricultural land, concurrent with increased demand for oil, there is much current interest in raising oil crop productivity.
Cazenave-Gassiot, Amaury, Haslam, R. P., Amaury Cazenave-Gassiot, Haslam, Richard P., Woodfield, Helen K., Helen K. Woodfield, Wenk, M.R., Irina A. Guschina, Markus R. Wenk, Cazenave-Gassiot, A., Richard P. Haslam, Wenk, Markus R., Guschina, I.A., Woodfield, H.K., Harwood, J.L., John L. Harwood, Harwood, John L., Guschina, Irina A.   +17 more
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Secondary lipid accumulation in lysosomal disease

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2009
Lysosomal diseases are inherited metabolic disorders caused by defects in a wide spectrum of lysosomal and a few non-lysosomal proteins. In most cases a single type of primary storage material is identified, which has been used to name and classify the disorders: hence the terms sphingolipidoses, gangliosidoses, mucopolysaccharidoses, glycoproteinoses,
Walkley, Steven U., Vanier, Marie T.
openaire   +2 more sources

Chemical chaperone 4-phenyl butyric acid (4-PBA) reduces hepatocellular lipid accumulation and lipotoxicity through induction of autophagy[S]

Journal of Lipid Research, 2017
Defective autophagy has been linked to lipotoxicity in several cellular models. We aimed to investigate autophagy in lipid-stimulated hepatoma (Huh7) cells and tested whether 4-phenyl butyric acid (4-PBA), a chemical chaperone, has a beneficial role in ...
Ashraf U. Nissar, Love Sharma, Malik A. Mudasir, Lone A. Nazir, Sheikh A. Umar, Parduman R. Sharma, Ram A. Vishwakarma, Sheikh A. Tasduq   +7 more
doaj   +1 more source