Results 41 to 50 of about 3,316,815 (349)

Transcriptome analyses reveal reduced hepatic lipid synthesis and accumulation in more feed efficient beef cattle [PDF]

, 2018
peer-reviewedThe genetic mechanisms controlling residual feed intake (RFI) in beef cattle are still largely unknown. Here we performed whole transcriptome analyses to identify differentially expressed (DE) genes and their functional roles in liver ...
Fitzsimmons, Carolyn, Keogh, Kate, Li, Changxi, Mukiibi, Robert, Stothard, Paul, Vinsky, Michael, Waters, Sinead M.   +6 more
core   +3 more sources

Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease

Cellular and Molecular Life Sciences, 2018
Non-alcoholic fatty liver disease (NAFLD) is currently the world’s most common liver disease, estimated to affect up to one-fourth of the population.
D. H. Ipsen, J. Lykkesfeldt, P. Tveden-Nyborg   +2 more
semanticscholar   +1 more source

Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor. [PDF]

, 2016
Background and objectivesObesity is a global epidemic which increases the risk of the metabolic syndrome. Cathelicidin (LL-37 and mCRAMP) is an antimicrobial peptide with an unknown role in obesity.
Bakirtzi, K, Cheng, M, Fisseha, E, Fleshner, P, Gallo, RL, Hing, TC, Ho, S, Hoang-Ngoc Tran, D, Hoang-Yen Tran, D, Karagiannides, I, Koon, HW, Law, I, Lee, EC, Lee, JE, Li, Z, Mattai, SA, McGovern, DPB, Ortiz, C, Robbins, L, Sallam, T, Shieh, C, Shih, DQ, Sideri, A, Su, B, Targan, SR, Vu, M   +25 more
core   +1 more source

Lipid accumulation in macrophages confers protumorigenic polarization and immunity in gastric cancer

Cancer Science, 2020
Heterotypic interactions between tumor cells and macrophages can enable tumor progression and hold potential for the development of therapeutic interventions.
Qin Luo, Naisheng Zheng, Li Jiang, Tingting Wang, Peng Zhang, Yi Liu, P. Zheng, Weiwei Wang, Guo-hua Xie, Lei Chen, Dongdong Li, P. Dong, Xiangliang Yuan, Lisong Shen   +13 more
semanticscholar   +1 more source

Targeting MicroRNAs to Limit Myocardial Lipid Accumulation [PDF]

Circulation Research, 2015
Obesity and type 2 diabetes mellitus are major health concerns, with the incidence rapidly rising in the world. Among their many complications is an increased risk of developing heart failure.1,2 This increased incidence of heart failure in obese and diabetic individual occurs even when corrected for the increased prevalence of hypertension and ...
Gary D, Lopaschuk, John R, Ussher
openaire   +2 more sources

Inhibitory effects of compounds from the roots of Potentilla longifolia on lipid accumulation

PLoS ONE, 2020
Potentilla longifolia is a kind of Chaoyao medicine, which is a branch of traditional Chinese medicine. The plant is often referred to as ganyancao or ganyearmcao, which means that it has a significant therapeutic effect on liver inflammation.
Shengxi Lin, Xiaoyan Zhao, Yunpeng Sun, Huan Liu, Mingyang Shang, Jinyan Gong, Qianqian Ma, Guangchun Piao, Haidan Yuan, Leonidas Matsakas   +9 more
doaj   +2 more sources

Naringenin inhibits lipid accumulation by activating the AMPK pathway in vivo and vitro

Food Science and Human Wellness, 2023
The aim of this study was to explore the lipid-lowering effect of naringenin and the underlying mechanism in high-fat-diet-fed SD rats and 3T3-L1 cells. In this study, SD rats were divided into the normal chow diet group (NCD), high fat diet group (HFD),
Xiaoyu Cai, Songxue Wang, Huali Wang, Suwen Liu, Guishan Liu, Huibin Chen, Ji Kang, Hao Wang   +7 more
doaj   +1 more source

Synthesis and accumulation of a receptor regulatory protein associated with lipid droplet accumulation in 3T3-L1 cells

Journal of Lipid Research, 1998
Synthesis and accumulation of the recently identified prostaglandin F2α receptor regulatory protein (FPRP) was found to correlate closely with lipid droplet accumulation by 3T3-L1 preadipose cells.
D.J. Orlicky, J.G. Lieber, C.L. Morin, R.M. Evans   +3 more
doaj   +1 more source

Lipid accumulation product is a better predictor of metabolic syndrome in Chinese adolescents: a cross-sectional study

Frontiers in Endocrinology, 2023
AimConfirm and compare the degree of associations of non-traditional lipid profiles and metabolic syndrome (MetS) in Chinese adolescents, determine the lipid parameter with better predictive potential, and investigate their discriminatory power on MetS ...
Zi-yi Chen, Lei Liu, Xu-xiu Zhuang, Yi-cong Zhang, Ya-nan Ma, Yang Liu, De-liang Wen   +6 more
doaj   +1 more source

Characterization of key triacylglycerol biosynthesis processes in rhodococci. [PDF]

, 2016
Oleaginous microorganisms have considerable potential for biofuel and commodity chemical production. Under nitrogen-limitation, Rhodococcus jostii RHA1 grown on benzoate, an analog of lignin depolymerization products, accumulated triacylglycerols (TAGs ...
Amara, Sawsan, Diaz-Salazar, Carlos, Eltis, Lindsay D, Liu, Jie, Otani, Hiroshi, Seghezzi, Nicolas   +5 more
core   +2 more sources