Results 11 to 20 of about 14,816 (282)

Development of a monoclonal antibody and a lateral-flow device for the rapid detection of a Mucorales-specific biomarker

Frontiers in Cellular and Infection Microbiology, 2023
Mucoromycosis is a highly aggressive angio-invasive disease of humans caused by fungi in the zygomycete order, Mucorales. While Rhizopus arrhizus is the principal agent of mucoromycosis, other Mucorales fungi including Apophysomyces, Cunninghamella ...
Christopher R. Thornton, Christopher R. Thornton, Genna E. Davies, Laura Dougherty   +3 more
doaj   +2 more sources

Mucorales-Specific T Cells in Patients with Hematologic Malignancies. [PDF]

PLoS ONE, 2016
BACKGROUND:Invasive mucormycosis (IM) is an emerging life-threatening fungal infection. It is difficult to obtain a definite diagnosis and to initiate timely intervention.
Leonardo Potenza, Daniela Vallerini, Patrizia Barozzi, Giovanni Riva, Andrea Gilioli, Fabio Forghieri, Anna Candoni, Simone Cesaro, Chiara Quadrelli, Johan Maertens, Giulio Rossi, Giulio Rossi, Monica Morselli, Mauro Codeluppi, Cristina Mussini, Elisabetta Colaci, Andrea Messerotti, Ambra Paolini, Monica Maccaferri, Valeria Fantuzzi, Cinzia Del Giovane, Alessandro Stefani, Uliano Morandi, Rossana Maffei, Roberto Marasca, Franco Narni, Renato Fanin, Patrizia Comoli, Luigina Romani, Anne Beauvais, Pier Luigi Viale, Jean Paul Latgè, Russell E Lewis, Mario Luppi   +33 more
doaj   +3 more sources

Clinical performance of metagenomic next-generation sequencing for distinction and diagnosis of Mucorales infection and colonization [PDF]

Frontiers in Cellular and Infection Microbiology
Mucormycosis is a lethal fungal infection disease with high mortality rate. However, investigations assessing the value of metagenomic next-generation sequencing (mNGS) for distinguishing Mucorales infection from colonization are currently insufficient ...
Xiaoli Zhou, Chenxi Yang, Xin Liu, Jiaqiang Wang, Yanqiao Li, Lingai Pan, Shengkun Peng, Hua Yu, Xiren Deng   +8 more
doaj   +2 more sources

Evaluation of environmental Mucorales contamination in and around the residence of COVID-19-associated mucormycosis patients

Frontiers in Cellular and Infection Microbiology, 2022
IntroductionRecently, India witnessed an unprecedented surge of coronavirus disease 2019 (COVID-19)-associated mucormycosis (CAM) cases. In addition to patient management issues, environmental Mucorales contamination possibly contributed to the outbreak.
Anup K. Ghosh, Ravinder Singh, Snigdha Reddy, Shreya Singh, Shivaprakash M. Rudramurthy, Harsimran Kaur, Hansraj Choudhary, Arunaloke Chakrabarti   +7 more
doaj   +2 more sources

Accuracy of plasma cell-free DNA PCR for non-invasive diagnosis of mucormycosis [PDF]

Journal of Clinical Microbiology
Diagnosis of mucormycosis poses a substantial challenge due to the lack of a non-invasive biomarker and limitations of conventional diagnostics using invasive specimens.
Jordan Mah, Anthony Lieu, Veronica Nicholas, Angel Moreno, Kanagavel Murugesan, Indre Budvytiene, Niaz Banaei   +6 more
doaj   +2 more sources

Detection of <i>Mucorales</i> antigen in bronchoalveolar lavage samples using a newly developed lateral-flow device. [PDF]

J Clin Microbiol
A murine IgG2b monoclonal antibody, named TG11, binding to an extracellular polysaccharide antigen secreted by all Mucorales fungi has been recently developed and integrated into a lateral-flow device (TG11-LFD).
Rousselot J, Millon L, Scherer E, Bourgeois N, Imbert S, Dupont D, Debourgogne A, Maubon D, Bellanger AP, Thornton CR.   +9 more
europepmc   +2 more sources

Antifungal-resistant Mucorales in different indoor environments [PDF]

Mycology, 2019
This paper sought to address the prevalence of Mucorales in different indoor environments in Portugal. Environmental samples (183 in total) were collected at dwellings (n = 79) and workplaces (bakeries, swine farms, taxis, waste-sorting plants) (n = 93 ...
Liliana Aranha Caetano, Tiago Faria, Jan Springer, Juergen Loeffler, Carla Viegas   +4 more
doaj   +4 more sources

Breakthrough Mucormycosis Developing on Mucorales-Active Antifungals Portrays a Poor Prognosis in Patients with Hematologic Cancer

Journal of Fungi, 2021
Although breakthrough mucormycosis (BT-MCR) is known to develop on mold-active antifungals without Mucorales activity, it can also occur while on Mucorales-active antifungals.
Dierdre B. Axell-House, Sebastian Wurster, Ying Jiang, Andreas Kyvernitakis, Russell E. Lewis, Jeffrey J. Tarrand, Issam I. Raad, Dimitrios P. Kontoyiannis   +7 more
doaj   +2 more sources

Interlaboratory assays from the fungal PCR Initiative and the Modimucor Study Group to improve qPCR detection of Mucorales DNA in serum: one more step toward standardization

Journal of Clinical Microbiology
The aim of this study was to identify parameters influencing DNA extraction and PCR amplification efficiencies in an attempt to standardize Mucorales qPCR.
S. Rocchi, E. Scherer, P. L. White, Audrey Guitton, Alexandre Alanio, Françoise Botterel, M. Bougnoux, M. J. Buitrago, Massimo Cogliati, M. Cornu, Céline Damiani, J. Denis, D. Dupont, S. Fuchs, Rebecca Gorton, Pieter-Jan Haas, Ferry Hagen, R. Hare, Xavier Iriart, C. Klaassen, M. Lackner, Martina Lengerova, W. Melchers, F. Morio, Philippe Poirier, Jan Springer, S. Valot, Birgit Willinger, Cristina Mazzi, Mario Cruciani, R. Barnes, J. P. Donnelly, Jurgen Loeffler, Laurence Millon   +33 more
semanticscholar   +2 more sources

Updates on the Taxonomy of Mucorales with an Emphasis on Clinically Important Taxa [PDF]

Journal of Fungi, 2019
Fungi of the order Mucorales colonize all kinds of wet, organic materials and represent a permanent part of the human environment. They are economically important as fermenting agents of soybean products and producers of enzymes, but also as plant ...
G. Walther, Lysett Wagner, O. Kurzai
semanticscholar   +2 more sources