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Mucorales Species and Macrophages [PDF]
Mucormycosis is an emerging fungal infection caused by Mucorales with an unacceptable high mortality rate. Mucorales is a complex fungal group, including eleven different genera that can infect humans.
Francisco E. Nicolás +5 more
doaj +6 more sources
IntroductionSerum Mucorales PCR can precede the final diagnosis of invasive mucormycosis by several days or weeks and could therefore be useful as a non-invasive screening tool.MethodsWe assessed the performance of a commercial Mucorales PCR assay ...
Robina Aerts +2 more
exaly +3 more sources
BackgroundIn this study, we used real-time quantitative PCR (RQ-PCR) to rapidly detect Mucorales and Aspergillus in formalin-fixed, paraffin-embedded (FFPE) samples, targeting 18SrRNA gene and 28SrRNA gene. Identification of Mucorales and Aspergillus was
Xiaolin Jiang +3 more
exaly +3 more sources
Innate and Adaptive Immunity to Mucorales [PDF]
Mucormycosis is an invasive fungal infection characterised by rapid filamentous growth, which leads to angioinvasion, thrombosis, and tissue necrosis. The high mortality rates (50–100%) associated with mucormycosis are reflective of not only the aggressive nature of the infection and the poor therapeutics currently employed, but also the failure of the
Harlene Ghuman, Kerstin Voelz
openalex +5 more sources
Mucorales-Specific T Cells in Patients with Hematologic Malignancies. [PDF]
BACKGROUND:Invasive mucormycosis (IM) is an emerging life-threatening fungal infection. It is difficult to obtain a definite diagnosis and to initiate timely intervention.
Leonardo Potenza +33 more
doaj +3 more sources
Diagnosis of Mucormycosis: Current Situation, Challenges and Future Prospects. [PDF]
ABSTRACT Mucormycosis, an aggressive fungal infection caused by members of the order Mucorales, progresses rapidly and is associated with high mortality, particularly in immunocompromised hosts such as patients with uncontrolled diabetes, transplant recipients or those with COVID‐19‐associated immunosuppression. Early diagnosis remains challenging with
Qu Y, Xiao Y, Liu L, Qu J.
europepmc +2 more sources
Mucorales from the semiarid of Pernambuco, Brazil [PDF]
Nineteen taxa of Mucorales, belonging to Absidia, Apophysomyces, Cunninghamella, Fennellomyces, Lichtheimia, Mucor, Mycotypha, Rhizopus and Syncephalastrum were isolated from 36 composite soil samples in three semiarid areas in the State of Pernambuco (Triunfo, Cabrobó and Belém de São Francisco), Northeast Brazil, which are characterized by Caatinga ...
André Luiz Cabral Monteiro de Azevedo Santiago +2 more
openalex +5 more sources
Cutaneous Mucormycosis Clinically Mimicking Necrotizing Fasciitis in a Patient Without Active Immunosuppression [PDF]
ABSTRACT Cutaneous mucormycosis is a rare invasive fungal infection caused by fungi of the order Mucorales. Although it classically occurs in immunocompromised hosts, traumatic or minor cutaneous inoculation may result in infection even in patients without active immunosuppression.
İnan A +5 more
europepmc +2 more sources
Antifungal-resistant Mucorales in different indoor environments
This paper sought to address the prevalence of Mucorales in different indoor environments in Portugal. Environmental samples (183 in total) were collected at dwellings (n = 79) and workplaces (bakeries, swine farms, taxis, waste-sorting plants) (n = 93 ...
Liliana Aranha Caetano +2 more
exaly +2 more sources
Clinical performance of metagenomic next-generation sequencing for distinction and diagnosis of Mucorales infection and colonization [PDF]
Mucormycosis is a lethal fungal infection disease with high mortality rate. However, investigations assessing the value of metagenomic next-generation sequencing (mNGS) for distinguishing Mucorales infection from colonization are currently insufficient ...
Xiaoli Zhou +8 more
doaj +2 more sources

