Results 51 to 60 of about 645,469 (305)

Dextran sulfate enhances the level of an oxidative DNA damage biomarker, 8-oxo-7,8-dihydro-2 0-deoxyguanosine, in rat colonic mucosa [PDF]

, 1998
Dextran sodium sulfate (DSS) given in drinking water can induce colonic Inflammation and produce colorectal tumors in rodents, although it is not directly genotoxic.
Petit, Claude, Embvani, E., Jaeg, Jean-Philippe, Tardieu, Didier, Corpet, Denis E., Cadet, Jean   +5 more
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Serum and Plasma Zinc and Copper Levels in Oral Leukoplakia: A Systematic Review and Meta-Analysis

Antioxidants
Background: Oral leukoplakia (OL) is a common oral potentially malignant disorder in which oxidative imbalance and altered trace-element homeostasis may contribute to pathogenesis.
Patryk Wiśniewski, Monika Stępniewska, Piotr Melion, Zuzanna Poloczek, Maksymilian Pawluczuk, Dawid Chodziński, Magdalena Sulewska, Małgorzata Pietruska   +7 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Clinical and Radiological Evaluation of Flap and Flapless Procedures with Biomaterials in Alveolar Ridge Preservation

Journal of Functional Biomaterials
Although ridge preservation procedures have been shown to prevent post-extraction bone loss, the effectiveness of using a flap or flapless surgical approach remains unclear.
Ewa Dolińska, Ewa Duraj, Marcin Bernaczyk, Magdalena Sulewska, Małgorzata Pietruska   +4 more
doaj   +1 more source

Mucosa associated lymphoid tissue lymphoma of the thyroid gland: a case report and literature review = MALT linfoma della tiroide: caso clinico e revisione della letteratura [PDF]

, 2012
Mucosa associated lymphoid tissue (MALT) lymphomas are low-grade, non-Hodgkin’s B cell lymphomas, mainly occurring in the gastrointestinal tract, but also in other tissues.
Paliogiannis, Panagiotis, Pulighe, Fabio, Pisano, Ilia Patrizio, Trignano, Mario, Attene, Federico, Scognamillo, Fabrizio   +5 more
core  

Enjekte edilebilen trombositten zengin fibrin: Tıpta ve diş hekimliğinde yeni bir materyal [PDF]

, 2020
Blood concentrates have been used in medicine and dentistry for many years as a wide variety of products. However, injectable platelet-rich fibrin (i-PRF), an autogenous blood concentrate found three years ago, is noteworthy.
Zeliha Betül ÖZSAĞIR, Tunalı, Mustafa, Mustafa TUNALI, Özsağır, Zeliha Betül   +3 more
core   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Oral mucosal lesions in Polish patients with acute myeloid leukemia after allogeneic hematopoietic cell transplantation

Scientific Reports
The number of allogeneic hematopoietic cell transplantation constantly increases. Therefore, there is an urgent need to carefully analyze the general and oral health state of people with acute myeloid leukemia who underwent this procedure.
Aleksandra Wysocka-Słowik, Zuzanna Ślebioda, Barbara Dorocka-Bobkowska, Marzena Liliana Wyganowska   +3 more
doaj   +1 more source