IgG “Detoxes” the Intestinal Mucosa [PDF]
Secretory IgA is important in mucosal defense, but other, incompletely understood effectors exist. In this issue of Cell Host & Microbe, Kamada et al. (2015) show that IgG antibodies are produced against surface virulence factors of an intestinal attaching/effacing pathogen, bind to bacteria localized at the epithelium, and direct their destruction by ...
Eckmann, Lars, Stappenbeck, Thaddeus S.
openaire +2 more sources
Dendritic cell subsets in the intestinal lamina propria: ontogeny and function [PDF]
The intestinal mucosa is exposed to large amounts of foreign antigen (Ag) derived from commensal bacteria, dietary Ags, and intestinal pathogens. Dendritic cells (DCs) are believed to be involved in the induction of tolerance to harmless Ags and in ...
Agace +87 more
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Does CDX2 expression predict Barrett's metaplasia in oesophageal columnar epithelium without goblet cells? [PDF]
Background: Intestinal metaplasia (Barrett's oesophagus), but not cardiac-type mucosa in columnar-lined oesophagus, is regarded as premalignant. As intestinal metaplasia and cardiac-type mucosa are endoscopically indiscernible, it is difficult to take ...
Bax, D.A. (Dorine) +8 more
core +1 more source
To respond or not to respond - a personal perspective of intestinal tolerance [PDF]
For many years, the intestine was one of the poor relations of the immunology world, being a realm inhabited mostly by specialists and those interested in unusual phenomena.
A Besredka +142 more
core +1 more source
Iron metabolism of intestinal mucosa in various blood diseases [PDF]
For the investigation of iron metabolism in the intestinal mucosa in various blood diseases, intestinal biopsy (duodenum) was performed on 10 healthy controls and 35 cases with various blood diseases.
Kimura, Ikuro +2 more
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Micromanagement in the gut : microenvironmental factors govern colon mucosal biofilm structure and functionality [PDF]
The human gut microbiome provides us with functional features that we did not have to evolve ourselves and can be viewed as a structured microbial community that operates like a microbial organ within the human host.
De Weirdt, Rosemarie, Van de Wiele, Tom
core +2 more sources
Early markers of angiogenesis and ischemia during bowel conduit neovascularization [PDF]
Background Bowel flaps are a good and reliable method to restore the continuity of the aerodigestive tract. Radiated fields, contaminated recipient sites, or depleted recipient vessels may increase the risk for ischemic injury after transfer.
Chen, Hung-chi +7 more
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Fibrotic and Vascular Remodelling of Colonic Wall in Patients with Active Ulcerative Colitis [PDF]
open16noIntestinal fibrosis is a complication of inflammatory bowel disease [IBD]. Although fibrostenosis is a rare event in ulcerative colitis [UC], there is evidence that a fibrotic rearrangement of the colon occurs in the later stages.
Bassotti, Gabrio +15 more
core +2 more sources
Detection of inflammation- and neoplasia-associated alterations in human large intestine using plant/invertebrate lectins, galectin-1 and neoglycoproteins [PDF]
Commonly, plant and invertebrate lectins are accepted glycohistochemical tools for the analysis of normal and altered structures of glycans in histology and pathology.
Bosbach, R. +3 more
core +1 more source
Occurrence of gastric cancer and carcinoids in atrophic gastritis during prospective long-term follow up [PDF]
Objective. Atrophic gastritis (AG) is a risk condition for gastric cancer and type I gastric carcinoids. Recent studies assessing the overall risk of gastric cancer and carcinoids in AG at long-term follow up are lacking.
Annibale, Bruno +6 more
core +2 more sources

