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The mechanism of chloroquine/hydroxychloroquine and its application in stomatological diseases

open access: yes口腔疾病防治, 2021
Chloroquine and hydroxychloroquine are both classic 4-aminoquinoline antimalarial drugs with similar chemical structures and mechanisms of action.
LIN Lin, WU Kaihui, WANG Wenmei
doaj   +1 more source

Armed to the Teeth—The Oral Mucosa Immunity System and Microbiota

open access: yesInternational Journal of Molecular Sciences, 2022
The oral cavity is inhabited by a wide spectrum of microbial species, and their colonization is mostly based on commensalism. These microbes are part of the normal oral flora, but there are also opportunistic species that can cause oral and systemic ...
M. Ptasiewicz   +6 more
semanticscholar   +1 more source

The Bigger Picture: Why Oral Mucosa Heals Better Than Skin

open access: yesBiomolecules, 2021
Wound healing is an essential process to restore tissue integrity after trauma. Large skin wounds such as burns often heal with hypertrophic scarring and contractures, resulting in disfigurements and reduced joint mobility.
M. Waasdorp   +5 more
semanticscholar   +1 more source

Tissue-engineered Oral Mucosa [PDF]

open access: yesJournal of Dental Research, 2012
Advances in tissue engineering have permitted the three-dimensional (3D) reconstruction of human oral mucosa for various in vivo and in vitro applications. Tissue-engineered oral mucosa have been further optimized in recent years for clinical applications as a suitable graft material for intra-oral and extra-oral repair and treatment of soft-tissue ...
Moharamzadeh, K.   +7 more
openaire   +3 more sources

An Overview of Physical, Microbiological and Immune Barriers of Oral Mucosa

open access: yesInternational Journal of Molecular Sciences, 2021
The oral mucosa, which is the lining tissue of the oral cavity, is a gateway to the body and it offers first-line protection against potential pathogens, exogenous chemicals, airborne allergens, etc.
S. Şenel
semanticscholar   +1 more source

Immune Tolerance in the Oral Mucosa

open access: yesInternational Journal of Molecular Sciences, 2021
The oral mucosa is a site of intense immune activity, where a large variety of immune cells meet to provide a first line of defense against pathogenic organisms.
Hector F. Pelaez-Prestel   +3 more
semanticscholar   +1 more source

Candida albicans commensalism in the oral mucosa is favoured by limited virulence and metabolic adaptation

open access: yesbioRxiv, 2021
As part of the human microbiota, the fungus Candida albicans colonizes the oral cavity and other mucosal surfaces of the human body. Commensalism is tightly controlled by complex interactions of the fungus and the host to preclude fungal elimination but ...
C. Lemberg   +10 more
semanticscholar   +1 more source

High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa

open access: yesInternational Journal of Oral Science, 2020
It has been reported that ACE2 is the main host cell receptor of 2019-nCoV and plays a crucial role in the entry of virus into the cell to cause the final infection.
Hao Xu   +7 more
semanticscholar   +1 more source

In vitro three-dimensional organotypic culture models of the oral mucosa

open access: yesIn Vitro Cellular & Developmental Biology - Animal, 2021
Three-dimensional, organotypic models of the oral mucosa have been developed to study a wide variety of phenomena occurring in the oral cavity. Although a number of models have been developed in academic research labs, only a few models have been ...
M. Klausner, Y. Handa, S. Aizawa
semanticscholar   +1 more source

Analysis of the bacterial flora of periodontal pockets and evaluation of the diagnostic value and the validity of using the PET test in the detection of Sockransky’s red complex pathogens at various stages and degrees of periodontitis

open access: yesJournal of Education, Health and Sport, 2022
Introduction: In microbiological diagnostics, a significant role is played by the PET test based on a polymerase chain reaction developed thanks to medical engineering methods, which, by amplifying specific fragments of genetic material, enables the ...
Aleksandra Adamus   +6 more
doaj   +1 more source

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