Results 71 to 80 of about 73,485 (336)

Adjuvant External Beam Radiotherapy in Differentiated Thyroid Cancers: An Audit of Clinical Practice, Adapting to New Evidence

Head &Neck, EarlyView.
ABSTRACT Introduction There is limited evidence on the role of adjuvant external beam radiotherapy in differentiated thyroid cancer (DTC). Methods We conducted a retrospective study of patients with DTC treated with adjuvant Intensity Modulated radiotherapy (IMRT) from 2011 to 2024.
Sarbani Ghosh Laskar, Samarpita Mohanty, Shwetabh Sinha, Anuj Kumar, Gouri Pantvaidya, Shivakumar Thiagarajan, Ashwini Budrukkar, Monali Swain, Anuja Deshmukh, Deepa Nair, Richa Vaish, Vidisha Tuljapurkar, Chandrashekhar Dravid, Sudhir Nair, Poonam Joshi, Rathan Shetty, Arjun Gurmeet Singh, Pankaj Chaturvedi   +17 more
wiley   +1 more source

Oral mucosa tissue gene expression profiling before, during, and after radiation therapy for tonsil squamous cell carcinoma.

PLoS ONE, 2018
BACKGROUND:Radiation-therapy (RT) induces mucositis, a clinically challenging condition with limited prophylactic interventions and no predictive tests.
Mette Marcussen, Mads Sønderkær, Julie Støve Bødker, Maria Andersen, Søren Nielsen, Charles Vesteghem, Ilse Christiansen, Olav Jonas Bergmann, Martin Bøgsted, Karen Dybkær, Mogens Vyberg, Hans Erik Johnsen   +11 more
doaj   +1 more source

Topical Tocopherol for treatment of reticular oral lichen planus: randomized, double-blind, crossover study [PDF]

, 2016
This randomized, double-blind, placebo-controlled crossover study assessed the efficacy of topical tocopherol acetate compared with placebo in easing oral discomfort in patients with reticular oral lichen planus (ROLP)
Bacci, Christian, Frigo, Anna Chiara, Sbricoli, Luca, Stellini, Edoardo, Valente, Marialuisa, Vanzo, Veronica   +5 more
core   +1 more source

Prophylactic Versus Reactive (PvR) Feeding in Patients Undergoing (Chemo)radiation in Head and Neck Cancers: Results of a Phase III Randomized Controlled Trial

Head &Neck, EarlyView.
ABSTRACT Background Optimal feeding strategy (Prophylactic vs. Reactive) during Radiation Therapy (RT) for Head and Neck Cancers (HNC) remains to be established. Methods This phase III trial randomized (1:1) patients of HNC to prophylactic [nasogastric tube (NGT) placed at least 1 day before RT starting] versus reactive arm (NGT when required).
Sarbani Ghosh Laskar, Shwetabh Sinha, Meenakshi Jeeva, Meetakshi Gupta, Shreyasee Karmakar, Anuj Kumar, Samarpita Mohanty, Purabi Mahajan, Shivashankar Timmanpyati, Arun Balaji, Ashwini Budrukkar, Monali Swain, Faizalam Khan, Gouri Pantvaidya, Anuja Deshmukh, Deepa Nair, Devendra Chaukar, Prathamesh Pai, Shiva Thiagarajan, Richa Vaish, Vidisha Tuljapurkar, Pankaj Chaturvedi   +21 more
wiley   +1 more source

Real‐world study on fluoropyrimidine‐related toxicity outcomes in cancer patients with select DPYD variant alleles that received DPYD genotype‐guided dosing

International Journal of Cancer, EarlyView.
What's New? Fluoropyrimidines, a key component of chemotherapy regimens for a variety of solid tumors, can cause severe toxicity. Patients who have specific genetic variants in the DPYD gene, which encodes an enzyme that inactivates fluoropyrimidines, have increased susceptibility to this toxicity.
Sofía L. J. Peeters, Didier Meulendijks, Zerina Kadric, Sara Ibrovic, Geert‐Jan Creemers, Vanja Milosevic, Matthijs van de Poll, Lieke H. J. Simkens, Birgit A. L. M. Deiman, Hans Gelderblom, Henk‐Jan Guchelaar, Anna M. J. Thijs, Maarten J. Deenen   +12 more
wiley   +1 more source

Adjunctive Treatments for the Prevention of Chemotherapy- and Radiotherapy-Induced Mucositis

Integrative Cancer Therapies, 2018
Background: Chemoradiotherapy-associated mucositis can manifest as pain, inflammation, dysphagia, diarrhea, weight loss, rectal bleeding, and infection. Mucositis is a major dose-limiting side effect of chemotherapy, affecting nutritional intake and oral
Michael Thomsen MSc, Luis Vitetta PhD
doaj   +1 more source

Psychological profile of laryngectomized patients [PDF]

, 2016
Larynx cancer is one of the most susceptible form of cancer susceptible to induce alteration of the patient’s psychological profile due to the social role that the larynx has in communication.
Balalau, Cristian, Bertesteanu, Serban V, Paun, Oana A, Popescu, Bogdan, Scaunasu, Razvan V   +4 more
core   +3 more sources

The Role of Interleukin‐23 and Interleukin‐17 in Peri‐Implant Crevicular Fluid of Subjects With Peri‐Implant Disease: A Systematic Review

Journal of Clinical Laboratory Analysis, EarlyView.
The role of IL‐23/IL‐17 cytokine axis in peri‐implant disease. ABSTRACT Background Activation of the IL‐23/IL‐17 cytokine axis could trigger peri‐implant bone loss. The aim of this review was to analyze whether in people with peri‐implantitis (PI) and peri‐implant mucositis (PM) the concentrations of the interleukin‐23 and interleukin‐17 in peri ...
Mario Alberto Alarcón‐Sánchez, Julieta Sarai Becerra‐Ruiz, Ruth Rodríguez‐Montaño, Sarah Monserrat Lomelí‐Martínez, Lilibeth‐Stephania Escoto‐Vasquez, Artak Heboyan   +5 more
wiley   +1 more source

The Effect of Rabdosia rubescens on Radiotherapy-Induced Oral Mucositis in Nasopharyngeal Carcinoma Patients: A Phase II Clinical Study

Integrative Cancer Therapies
Purpose: Radiotherapy-induced oral mucositis is the most common side effect in nasopharyngeal carcinoma (NPC) patients. We aimed to evaluate the efficacy and safety of Rabdosia rubescens drop pills in NPC patients with radiation-induced oral mucositis ...
Lu Li MS, Yecai Huang MD, Jun Yin MD, Peng Xu MS, Mei Lan MD, Churong Li MS, Yunxiang Qi MD, Ke Xu MS, Bosen Li MS, Yukun Luo MS, Qinghua Jiang MS, Shanshan Peng MS, Jinyi Lang MD, Mei Feng MD   +13 more
doaj   +1 more source

First-in-Human Phase I Study to Evaluate the Brain-Penetrant PI3K/mTOR Inhibitor GDC-0084 in Patients with Progressive or Recurrent High-Grade Glioma. [PDF]

, 2020
PurposeGDC-0084 is an oral, brain-penetrant small-molecule inhibitor of PI3K and mTOR. A first-in-human, phase I study was conducted in patients with recurrent high-grade glioma.Patients and methodsGDC-0084 was administered orally, once daily, to ...
Cloughesy, Timothy F, Coimbra, Alexandre F, Ellingson, Benjamin M, Gerstner, Elizabeth, Lee, Eudocia Q, Lu, Xuyang, Morrissey, Kari M, Mueller, Lars U, Olivero, Alan G, Rodon, Jordi, Wen, Patrick Y, Wilson, Timothy R   +11 more
core