Results 231 to 240 of about 120,394 (280)

Progress in Surface‐Enhanced Raman Scattering‐Based Volatile Organic Compounds Detection: Materials, Application, and Prospects

open access: yesRare Metals, EarlyView.
ABSTRACT The detection of volatile organic compounds (VOCs) holds significant implications in environmental monitoring and disease diagnosis. Traditional gas detection technologies are constrained by complex operation and high cost, thereby failing to satisfy real‐time detection demands.
Yuening Wang   +11 more
wiley   +1 more source

Epigenetic Dysregulation of the NKX2‐1/SPDEF Axis Drives Persistent Goblet Cell Differentiation and Epithelial Barrier Dysfunction in Chronic Obstructive Pulmonary Disease

open access: yesRespirology, EarlyView.
This study investigated airway epithelial barrier dysfunction persistence in ex‐smokers with COPD and underlying mechanisms using single‐cell RNA and ATAC sequencing. Epigenetic NKX2‐1/SPDEF dysregulation maintains goblet cell hyperplasia and barrier dysfunction despite long‐term smoking cessation.
Ayaka Shiota   +17 more
wiley   +1 more source

Responsive liquid metal materials towards unstructured environment

open access: yesResponsive Materials, EarlyView.
Room‐temperature liquid metals integrate conductivity, deformability, and interfacial dynamics, enabling robust performance in unstructured environments. This review highlights key properties, requirements, and applications across in vivo, underwater, natural, space, and radiation settings, with advances in sensing, actuation, thermal regulation, and ...
Bo Yuan   +5 more
wiley   +1 more source

Nasal Delivery of mRNA Using Thermoresponsive Gellable Aqueous Biphasic Systems

open access: yesSmall, EarlyView.
Nasal delivery of mRNA using gellable aqueous biphasic systems (ABS) represents a noninvasive alternative while reducing the need for trained professionals and cold chain storage. Composed of gelatin, PEG, and water, these thermoresponsive hydrogels ensure controlled mRNA delivery and prolonged retention at the nasal mucosa, improving transfection ...
Bojan Kopilovic   +4 more
wiley   +1 more source

Bioengineered Bacterial Vesicles and Biomimetic Hybrids Eliminate Biofilms and Balance the Gut Microbiome

open access: yesSmall, EarlyView.
Biomimetic nanocarriers based on liposomes and Myxobacteria outer‐membrane vesicles (OMVs) are effective antibiotic delivery systems. Hybrids have a higher drug loading and can target intracellular pathogens, while OMVs evade immune clearance. Biomimetic nanoantibiotics effectively eliminate the biofilms of Gram‐negative bacteria. Besides, Myxobacteria
Leila Pourtalebi Jahromi   +13 more
wiley   +1 more source

Wearable Sensors Fabricated by 3D‐Printed Composite Hydrogel with 2D Fillers

open access: yesSmall Methods, EarlyView.
This review explores how 3D printing integrates 2D conductive fillers into hydrogel matrices to fabricate high‐performance flexible sensors. By tailoring microstructures and nanomaterial interactions, these devices achieve enhanced sensitivity, durability, and environmental adaptability for healthcare monitoring, human‐machine interfaces, and robotic ...
Yaxuan Li   +5 more
wiley   +1 more source

Feasibility and acceptability of meticillin‐resistant Staphylococcus aureus biosecurity measures in equine facilities: A cross‐sectional study

open access: yesVeterinary Record, EarlyView.
Abstract Background Biosecurity measures are recommended in stables housing meticillin‐resistant Staphylococcus aureus (MRSA)‐positive horses, but their feasibility and acceptability, as well as their implementation barriers, remain unclear. Methods A cross‐sectional study was conducted among clients of a veterinary teaching hospital using an online ...
Pauline Planes   +3 more
wiley   +1 more source

Single‐cell RNA sequencing revealed the T‐cell heterogeneity and exhaustion subsets of Helicobacter pylori‐induced gastritis‐to‐cancer transformation

open access: yesVIEW, EarlyView.
H. pylori infection is a major cause of stomach cancer, but its effect on immune cells in tumors is unclear. Using single‐cell sequencing, we mapped the stomach tumor environment and discovered a specific exhausted T‐cell subtype, marked by the FYB1 gene, that is abundant in H. pylori‐positive tumors and linked to patient prognosis. Our findings reveal
Yanhui Yang   +22 more
wiley   +1 more source

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