Results 231 to 240 of about 122,849 (305)

Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target‐Driven Drug Discovery

open access: yesMedicinal Research Reviews, Volume 46, Issue 4, Page 921-944, July 2026.
ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano   +4 more
wiley   +1 more source

Paediatric Acute Generalised and Localised Exanthematous Pustulosis: A Systematic Review

open access: yes
JEADV Clinical Practice, Volume 5, Issue 2, Page 678-681, June 2026.
Miranda K. Branyiczky   +6 more
wiley   +1 more source

Sustainable Metal Recovery From E‐Waste: Exploring Greener Leachates in Hydrometallurgical Processes

open access: yesMetalMat, EarlyView.
Recycling of electronic waste to synthesize valuable metals using green leachate. ABSTRACT The accumulation of electronic waste (e‐waste) poses environmental hazards and leads to the loss of valuable metals such as gold, silver, copper, and rare earth elements.
Shassatha Paul Saikat   +4 more
wiley   +1 more source

Post‐Traumatic Facial Macules

open access: yes
JEADV Clinical Practice, EarlyView.
Molly Papadopoullos   +3 more
wiley   +1 more source

Endoplasmic reticulum stress and the unfolded protein response in lung diseases: molecular pathways and therapeutic interventions

open access: yesThe Journal of Pathology, Volume 269, Issue 3, Page 268-283, July 2026.
Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song   +6 more
wiley   +1 more source

The Airway Epithelial Barrier in Childhood Asthma: A Central Player in Glucocorticoid Therapy, Resistance, and Severe Asthma

open access: yesPediatric Discovery, EarlyView.
ABSTRACT Childhood asthma remains a global public health challenge with suboptimal control, despite the availability of inhaled corticosteroids (ICS) as first‐line therapy. Glucocorticoids suppress inflammation and protect the airway epithelial barrier (AEB) via genomic and nongenomic pathways.
Tangqiaochu Gan, Zhou Fu, Chao Niu
wiley   +1 more source

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