Results 41 to 50 of about 1,109,385 (152)

Emerging Paediatric Uses of Dupilumab Beyond Approvals

Clinical &Experimental Allergy, EarlyView.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese, Anna Calamita, Diletta D'Angelo, Alessia Marseglia, Esther Mesa Lombardero, Sara Pedersoli, Micol Tedeschi, Mara De Amici, Sara Manti, Valeria Brazzelli, Amelia Licari, Gian Luigi Marseglia   +11 more
wiley   +1 more source

Rapid effector function of circulating NC16A-specific T cells in individuals with mucous membrane pemphigoid

, 2004
Background Mucous membrane pemphigoid (MMP) is a chronic blistering skin disease frequently associated with circulating autoantibodies directed to a number of antigens including the NC16A region of BP180.
Ogg, GS, Jones, L, Arsecularatne, G, King, AS, Black, A., Seneviratne, SL, Winsey, S, Wojnarowska, F   +7 more
core   +1 more source

Rapid Disease Control in First-Line Therapy-Resistant Mucous Membrane Pemphigoid and Bullous Pemphigoid with Omalizumab as Add-On Therapy: A Case Series Of 13 Patients

Frontiers in Immunology, 2022
The role of IgE autoantibodies has been demonstrated in the pathogenesis of bullous pemphigoid for many years. Recently, omalizumab (OMZ), a humanized monoclonal anti-IgE antibody that depletes total serum IgE, has been used off-label in a few case ...
Marina Alexandre, Gérôme Bohelay, Gérôme Bohelay, Thomas Gille, Thomas Gille, Christelle Le Roux-Villet, Isaac Soued, Florence Morin, Frédéric Caux, Frédéric Caux, Sabine Grootenboer-Mignot, Catherine Prost-Squarcioni, Catherine Prost-Squarcioni, Catherine Prost-Squarcioni   +13 more
doaj   +1 more source

Anti-laminin 332 mucous membrane pemphigoid in a young woman treated with rituximab [PDF]

, 2022
Mucous membrane pemphigoid, formerly known as cicatricial pemphigoid, is a rare and difficult-to-treat bullous disorder that occurs most commonly in older adults.
Braunlich, Katherine, Bisbee, Elizabeth, Porta, Adriana Della, Gitin, Alexander, Motaparthi, Kiran   +4 more
core   +1 more source

The role of inflammation and fibroblasts in conjunctival scarring in ocular mucous membrane pemphigoid [PDF]

, 2009
Ocular mucous membrane pemphigoid (ocular MMP) is a visually devastating disease where up to 30% of patients become blind due to the consequences of conjunctival inflammation and aggressive fibrosis.
Saw, V.P.J.
core  

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra, Cecile Wasielewski, Bruno Špiljak, Maja Sabalić‐Schoener, Sebastien Jungo, Ivan Alajbeg   +5 more
wiley   +1 more source

Mucous Membrane Pemphigoid-Immunofluorescent Studies

, 1969
Mucous membrane pemphigoid differs from pemphigus vulgaris or bullous pemphigoid in clinical course, response to steroid therapy, and absence of characteristic antibodies.
Harvey A. Brody, Kirk D. Wuepper
core   +1 more source

Expert consensus on oral management in autoimmune bullous diseases, erythema multiforme and SJS/TEN

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This international Delphi study achieved expert consensus on 58 statements guiding the management of oral involvement in autoimmune bullous diseases, erythema multiforme and SJS‐TEN. The recommendations emphasize multidisciplinary care, oral hygiene and tailored topical, systemic and inpatient oral management.
Shalini Nayee, Molly Harte, Saskia Ingen‐Housz‐Oro, Milad Ameri, Sarah Walsh, Pascal Joly, Michael Ardern‐Jones, Vlaho Brailo, Marie‐Charlotte Brueggen, Christopher Bunker, Barbara Carey, Marco Carrozzo, Ser‐Ling Chua, Daniel Creamer, Donna Culton, Konstantina Delli, Marcio Diniz‐Freitas, Roni Dodiuk‐Gad, Sophie‐Myriam Dridi, Anne‐Laure Ejeil, Lars French, Krisztian Gaspar, Jon Higham, Barbara Horvarth, Esther Hullah, Sabine Jurge, Roddy McMillan, Helen McParland, Dedee Murrell, Martyn Ormond, Ana Poveda‐Gallego, Mahtab Samimi, Enno Schmidt, Martina Shephard, Tom Sollecito, Jennifer Taylor, Soner Uzun, Skaidra Valiukeviciene, Amanda Willis, Jane Setterfield   +39 more
wiley   +1 more source

Oral Health–Related Quality of Life and Depressive Symptoms in Oral Mucosal Diseases: A Cross‐Sectional Observational Pilot Study

Oral Diseases, EarlyView.
ABSTRACT Objectives To evaluate the association between oral mucosal diseases, oral health‐related quality of life (OHRQoL), and depressive symptoms, and to explore differences across categories. Materials and Methods In this cross‐sectional observational pilot study, consecutive outpatients with oral mucosal disease were enrolled at the Dental Clinic ...
Domenico Cutecchia, Tommaso Marvulli, Vittorio Dibello, Alberta Lucchese, Massimo Petruzzi, Domenico De Falco   +5 more
wiley   +1 more source

Management of Mucous Membrane Pemphigoid [PDF]

, 2021
Mucous membrane pemphigoid (MMP) is a chronic autoimmune subepithelial vesiculobullousdisorder predominantly affects the mucous membranes more frequently than the skin. Several targetantigens in basement membrane zone have been identified in MMP.
Sanguansin, Nutchaporn, Sappayatosok, Kraisorn   +1 more
core