Results 21 to 30 of about 1,065 (178)
Measurement of Trogocytosis: Quantitative Analyses Validated with Rigorous Controls
Current Protocols, Volume 3, Issue 10, October 2023., 2023 Abstract Trogocytosis is a process in which receptors on acceptor cells remove and internalize cognate ligands from donor cells. Trogocytosis has a profound and negative impact on mAb‐based cancer immunotherapy, as seen in the treatment of chronic lymphocytic leukemia (CLL) with CD20 mAbs, such as rituximab (RTX) and ofatumumab (OFA).
Ronald P. Taylor, Margaret A. Lindorfer
wiley +1 more source
Spatial Single Cell Analysis of Proteins in 2D Human Gastruloids Using Iterative Immunofluorescence
Current Protocols, Volume 3, Issue 10, October 2023., 2023 Abstract During development, cell signaling instructs tissue patterning, the process by which initially identical cells give rise to spatially organized structures consisting of different cell types. How multiple signals combinatorially instruct fate in space and time remains poorly understood.
Emily Freeburne +7 more
wiley +1 more source
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 43, Issue 8, Page 740-777, August 2023., 2023 Abstract Intravenous β‐lactam antibiotics remain a cornerstone in the management of bacterial infections due to their broad spectrum of activity and excellent tolerability. β‐lactams are well established to display time‐dependent bactericidal activity, where reductions in bacterial burden are directly associated with the time that free drug ...
Lisa T. Hong +16 more
wiley +1 more source
Ethics Committees' Practices in Healthcare, Banking and Research: Key Requirements for Their Functionality. [PDF]
J Eval Clin PractABSTRACT Rationale To meet concerns about ethical and unethical behavior in their work environments and workplaces, organizations began establishing ethics programs that contain ethics committees (ECs). There is now a tradition and diverse use of ECs for ethical decision‐making in many different organizational settings.
Arık T, Michl S.
europepmc +2 more sources
Distinct Roles of SLC26A3 and CFTR in Surface pH Regulation and Bicarbonate Secretion in Human Intestinal Epithelium. [PDF]
Acta Physiol (Oxf)ABSTRACT Background and Aims Colonic bicarbonate secretion is mediated by the chloride/bicarbonate exchanger SLC26A3 and the cystic fibrosis transmembrane conductance regulator (CFTR). Dysfunction of either causes luminal acidosis, altered mucus properties, and inflammation.
Amiri M, Salari A, Seidler U.
europepmc +2 more sources
Isolation of Adult Mouse Cardiac Fibroblasts
Current Protocols, Volume 3, Issue 7, July 2023., 2023 Abstract Fibroblasts are dynamic cells of mesenchymal origin that regulate tissue homeostasis, extracellular matrix production, and acute wound healing. Fibroblasts respond to tissue injury and inflammation by differentiating into myofibroblasts and secreting extracellular matrix proteins.
Abir Almazloum, Hadi Khalil
wiley +1 more source
CLINICAL - GENEALOGICAL ANALYSIS OF MUCOVISCIDOSIS
, 2020 1. The genetic relations in families with mucoviscidosis found in the present clinical material do not correspond to the true segregational relations of the frequencies of the affected children. 2. One of the reasons which influence the increase of the
Southern Caucasus Media group (8691924)
core +1 more source
Distal intestinal obstruction syndrome as unusual manifestation of cystic fibrosis. Report of a case
Acta Pediátrica de México, 2014 Introduction: Distal intestinal obstruction syndrome (DIOS) or “meconium ileus equivalent” is a blockage of the terminal ileum or of the ascending colon caused by inspissated stools in patients with cystic fibrosis (CF) beyond the neonatal period.
Gómez Ruiz Alejandro +2 more
doaj +1 more source
Severe liver dysfunction in an infant with cystic fibrosis masquerading as metabolic liver disease
Indian Journal of Pathology and Microbiology, 2016 We present a rare presentation of cystic fibrosis with neonatal cholestasis. Histological features of mucoviscidosis were present in liver involving the biliary tract, intestinal mucosa, pancreas, and lung.
K P Srikanth +3 more
doaj +1 more source
Histopathological effects of Doxorubicin on pancreas in male Albino rats [PDF]
Iraqi Journal of Veterinary Sciences, 2015 The aim of this study was to investigate the histopathological side effects of doxorubicin on pancreas tissue in male albino rats Rattus norvegicus. This study were used 55 adult rats (2.5-3.5) month of age.
I.A. Ali, H.J. Jumaa, H.Kh. Ismael
doaj +3 more sources