Results 51 to 60 of about 1,065 (178)

Protection‐Free, Two‐step Synthesis of C5‐C Functionalized Pyrimidine Nucleosides

open access: yesCurrent Protocols, Volume 4, Issue 2, February 2024.
Abstract A simple, reliable, and efficient method for the gram‐scale chemical synthesis of pyrimidine nucleosides functionalized with C5‐carboxyl, nitrile, ester, amide, or amidine, starting from unprotected uridine and cytidine, is described. The protocol involves the synthesis of 5‐trifluoromethyluridine and 5‐trifluoromethylcytidine with Langlois ...
Karolina Podskoczyj   +3 more
wiley   +1 more source

Aspectos celulares y moleculares de la mucoviscidosis

open access: yes, 1992
Cystic fibrosis, also known as CF or mucoviscidosis, is a serious inherited disorder that affects the lungs, digestive tract, and other organs.La mucoviscidosis o fibrosis quística (CF de  ''cystic fibrosis'')  es una ...
Muñoz Chapulí , Ramón
core  

Microbes Saving Lives and Reducing Suffering

open access: yes
Microbial Biotechnology, Volume 18, Issue 1, January 2025.
Kenneth Timmis   +26 more
wiley   +1 more source

GENE THERAPY IN MUCOVISCIDOSIS

open access: yes, 2023
<p><strong>Abstract</strong></p><p>The article describes the advantage of the CRISPR-Cas 9 gene editing method for the treatment of cystic fibrosis.
Talibova J.   +4 more
core   +1 more source

Treatment adherence in individuals with cystic fibrosis: An Observational Study

open access: yesJornal de Assistência Farmacêutica e Farmacoeconomia
Introduction: Low treatment adherence is a complex issue frequently observed in cystic fibrosis (CF) patients. Objective: To evaluate the self-reported treatment adherence rate and the rate determined based on pharmacy medication dispensation records in
Fernanda Fontelle   +5 more
doaj   +1 more source

The clinic peculiarities of the mucoviscidosis depending on the genotype

open access: yes, 1992
The families of patients with mucoviscidosis have been examined. The work is aimed at studying the clinic peculiarities of the mucoviscidosis depending on the type of mutations in gene CFTR.
Khafizova Zukhra Azizovna
core  

NTIBIOTICS SENSITIVITY OF STAPHYLOCOCCUS AUREUS, PSEUDOMONAS AERUGINOSA AND BACTERIA OF BURKHOLDERIA CEPACIA COMPLEX, PERSISTING IN LUNGS OF PATIENTS WITH MUCOVISCIDOSIS (MV)

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2015
Aim. Study the spectrum of resistance to antibiotics and its variability of Staphylococcus aureus, Pseudomonas aeruginosa and Вurkholderia cepacia complex (BCC), persisting in lungs of MV patients. Materials and methods. 312 strains of S.
L. R Avetisyan   +10 more
doaj  

Chronic polyposis rhinosinusitis in children with mucoviscidosis [PDF]

open access: yes
Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, Chişinău, Republica MoldovaIntroducere. Cea mai frecventă tulburare la pacienții cu mucoviscidoza este rinosinuzita cronică polipoasă, care se dezvoltă la 90% copii.
Maniuc, Mihail   +3 more
core  

Use of inhaled tobramycin in patients with cystic fibrosis

open access: yesТерапевтический архив, 2010
The results of a few studies evaluating the efficacy and safety of nebulized tobramycin solution used in patients with cystic fibrosis have been published to date. Pulmonary deposition of inhaled tobramycin and its lung produced concentrations are rather
A G Chermensky, M E Gembitskaya
doaj  

IMMUNE PREVENTION OF RESPIRATORY-SYNCYTIAL VIRAL INFECTION: 15 YEARS OF WORLD EXPERIENCE

open access: yesПедиатрическая фармакология, 2013
The article is dedicated to one of the most important issues of modern neonatology – prevention of respiratory-syncytial virus infection, which is a frequent cause of bronchiolites and pneumoniae in infants and neonates, especially premature infants. The
E. S. Keshishyan
doaj   +1 more source

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