Results 61 to 70 of about 2,128 (197)

In Vitro Assessment of Cardiac Fibroblast Activation at Physiologic Stiffness

Current Protocols, Volume 4, Issue 4, April 2024.
Abstract Cardiac fibroblasts (CF) are an essential cell type in cardiac physiology, playing diverse roles in maintaining structural integrity, extracellular matrix (ECM) synthesis, and tissue repair. Under normal conditions, these cells reside in the interstitium in a quiescent state poised to sense and respond to injury by synthesizing and secreting ...
Robert S. Goldsmith, Yao‐Chang Tsan, Rachel E. Scissors, Adam S. Helms, Matthew J. Brody   +4 more
wiley   +1 more source

Stigma and cystic fibrosis Estigma y fibrosis cística Estigma e fibrose c��stica

Revista Latino-Americana de Enfermagem, 2010
Cystic Fibrosis (CF), also known as Mucoviscidosis, is a chronic disease of autosomal recessive origin and so far incurable. This analysis considers some characteristics of patients and family members that indicate it is a stigmatizing disease.
Tainá Maues Peluci Pizzignacco, Débora Falleiros de Mello, Regina Aparecida Garcia de Lima   +2 more
doaj   +1 more source

Protection‐Free, Two‐step Synthesis of C5‐C Functionalized Pyrimidine Nucleosides

Current Protocols, Volume 4, Issue 2, February 2024.
Abstract A simple, reliable, and efficient method for the gram‐scale chemical synthesis of pyrimidine nucleosides functionalized with C5‐carboxyl, nitrile, ester, amide, or amidine, starting from unprotected uridine and cytidine, is described. The protocol involves the synthesis of 5‐trifluoromethyluridine and 5‐trifluoromethylcytidine with Langlois ...
Karolina Podskoczyj, Anna Kuszczynska, Agnieszka Dziergowska, Grazyna Leszczynska   +3 more
wiley   +1 more source

Safety, Tolerability, and Effects of Sodium Bicarbonate Inhalation in Cystic Fibrosis. [PDF]

, 2020
BACKGROUND:Among the many consequences of loss of CFTR protein function, a significant reduction of the secretion of bicarbonate (HCO3-) in cystic fibrosis (CF) is a major pathogenic feature.
Clinckspoor, Karl Jan, Conrad, Douglas, Gomez, Carla Cristina Souza, Levy, Carlos Emilio, Marson, Fernando Augusto Lima, Mauch, Renan Marrichi, Parazzi, Paloma Lopes Francisco, Peixoto, Andressa Oliveira, Pessine, Francisco Benedito Teixeira, Quinton, Paul Marquis, Ribeiro, Antônio Fernando, Ribeiro, José Dirceu, Ribeiro, Maria Ângela Gonçalves Oliveira   +12 more
core   +1 more source

Farmacogenética en Fibrosis Quística. [PDF]

, 2017
La fibrosis quística (a partir de ahora referida como FQ) fue descrita por primera vez en 1936 como una entidad separada. También recibía el nombre de “mucoviscidosis” debido a la acumulación de espesas secreciones mucosas que bloqueaban las vías aéreas,
Oraá Pérez, Javier
core  

Clinical experience with amikacin, a new aminoglycoside antibiotic [PDF]

, 1977
CITATION: Theron, F. P. & De Kock, M. A. 1977. Clinical experience with amikacin, a new aminoglycoside antibiotic. South African Medical Journal, 51(21):746-8.The original publication is available at http://www.samj.org.za[No abstract available]Publisher’
De Kock, M. A., Theron, F. P.
core  

Normal mucus formation requires cAMP-dependent HCO3- secretion and Ca2+-mediated mucin exocytosis. [PDF]

, 2013
  Evidence from the pathology in cystic fibrosis (CF) and recent results in vitro indicate that HCO3- is required for gel-forming mucins to form the mucus that protects epithelial surfaces.
Garcia, Mary Abigail S, Quinton, Paul M, Yang, Ning   +2 more
core   +1 more source

Learning from each other: ABC transporter regulation by protein phosphorylation in plant and mammalian systems [PDF]

, 2015
The ABC (ATP-binding cassette) transporter family in higher plants is highly expanded compared with those of mammalians. Moreover, some members of the plant ABCB subfamily display very high substrate specificity compared with their mammalian ...
Aryal, Bibek, Geisler, Markus, Laurent, Christophe   +2 more
core   +1 more source

Microbes Saving Lives and Reducing Suffering

Microbial Biotechnology, Volume 18, Issue 1, January 2025.
Kenneth Timmis, Zeynep Ceren Karahan, Juan Luis Ramos, Omry Koren, Ana Elena Pérez‐Cobas, Karen Steward, Victor de Lorenzo, Elisabetta Caselli, Margaret Douglas, Clarissa Schwab, Virginia Rivero, Rafael Giraldo, Junkal Garmendia, Raymond J. Turner, Jessamyn Perlmutter, José M. Borrero de Acuña, Pablo Ivan Nikel, Jerome Bonnet, Angela Sessitsch, James K. Timmis, Carla Pruzzo, M. Auxiliadora Prieto, Siavash Isazadeh, Wei E. Huang, Gerard Clarke, Danilo Ercolini, Max Häggblom   +26 more
wiley   +1 more source

Treatment adherence in individuals with cystic fibrosis: An Observational Study

Jornal de Assistência Farmacêutica e Farmacoeconomia
Introduction: Low treatment adherence is a complex issue frequently observed in cystic fibrosis (CF) patients. Objective: To evaluate the self-reported treatment adherence rate and the rate determined based on pharmacy medication dispensation records in
Fernanda Fontelle, LUCAS VIEIRA, ADRIANA FAIÇAL, JULIANA BRAZIL, MARCIA TEIXEIRA, EDNA LUCIA SOUZA   +5 more
doaj   +1 more source