Results 211 to 220 of about 197,930 (300)

A Practical Gut‐On‐Chip Workflow for Imaging‐Based Assessment of Epithelial Barrier Dynamics During E. coli Co‐Culture

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The intestinal epithelium and its resident microbiota form a dynamic interface that is central to gut homeostasis, but this interface is difficult to model with conventional tools. Static Transwell cultures lack physiological fluid shear, whereas animal models are costly and poorly suited to quantitative, high‐content imaging.
Shih‐Wei Chiang, Chuan‐Yi Yang, Guan‐Yu Chen   +2 more
wiley   +1 more source

Identification of Association Between Mucus Microbiota and Gene Expression in the Gill of a <i>Streptococcus agalactiae</i>-Resistant Nile Tilapia Strain Though Multi-Omics Analyses. [PDF]

Animals (Basel)
Wu H, Chen L, Huang T, Liu Y, Luo L, Kong L, Sun Y, Zhang W, Guo Z, He Z, Luo Y, Xiao J, Lu Y.   +12 more
europepmc   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Investigating sarcopenia and mucus plugging by chest computed tomography in patients with severe chronic obstructive pulmonary disease. [PDF]

Sci Rep
Petersen A, Hübner RH, Mall MA, Steffen IG, Weinheimer O, Witzenrath M, Saccomanno J, Elgeti T.   +7 more
europepmc   +1 more source

Eudragit®‐engineered pH‐responsive probiotic microspheres with enhanced gastrointestinal resistance and prolonged storage stability for inflammatory bowel disease therapy

BMEMat, EarlyView.
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng, Xiaomin Luo, Peng Zhang, Chen Yang, Yuniel Ma, Xinhua Liu   +5 more
wiley   +1 more source

A Zebrafish Galectin-1 Isoform Is Expressed in Skin and Gills and Binds to Bacteria, Bacterial Adhesin Receptors, and Epidermal Mucus Glycans. [PDF]

Int J Mol Sci
Feng C, Abernathy K, Wang S, Zong G, Zmora N, Shupp A, Iqbal M, Wang LX, Vasta GR.   +8 more
europepmc   +1 more source

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

Accelerated Mucopermeation and Penetration of the Polypeptide Antibiotic Colistin via Ionic Complexation with Polyphosphazene Carriers. [PDF]

ACS Omega
Stadler P, Kehrer S, Strasser P, Roschger C, Loretz B, Teasdale I.   +5 more
europepmc   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Mucoactive Agents in Muco-Obstructive Lung Diseases: A Critical Reappraisal of Pharmacological Effects and Clinical Outcomes. [PDF]

Pharmaceuticals (Basel)
Larobina D, Franzino G, Tescione F, Abrami M, Tierno D, Biasin A, Tonon F, De Nes A, Maggisano M, Confalonieri P, Carbone A, Confalonieri M, Grassi G, Di Gioia S, Grassi M, Conese M.   +15 more
europepmc   +1 more source