Results 241 to 250 of about 178,661 (314)

Protocol for the Preparation of Polyphenols‐Polysaccharide Nanoparticles

Food Chemistry International, EarlyView.
ABSTRACT Polyphenols, natural compounds abundantly distributed in plants, possess potent antioxidant and anti‐inflammatory activities and hold promising potential in cardiovascular protection and the management of metabolic disorders. Nevertheless, their intrinsic instability and low bioavailability severely constrain their practical and large‐scale ...
Chenxu Bao, Boqian He, Siyu Han, Jingying Liu, Jia Yan, Chunlin Li, Qian Wu   +6 more
wiley   +1 more source

ROMO1 is involved in airway mucus hypersecretion in COPD through the mitochondrial ROS-STAT6 pathway. [PDF]

Respir Res
Ge S, Li R, Li Y, Liu J, Yao S, Zhang R, Sun Y, Zhang T, Zhang J, Zhang M.   +9 more
europepmc   +1 more source

Unveiling CLC as a Central Regulator of Allergic Rhinitis via the CLC‐CCL26/POSTN Axis: An Integrated Bioinformatics and Experimental Study

Flavour and Fragrance Journal, EarlyView.
We unveil that CLC orchestrates the dual role of eosinophil recruitment via CCL26 and tissue remodelling via POSTN in allergic rhinitis, identifying it as a potential therapeutic target. ABSTRACT Allergic rhinitis (AR) is a chronic airway inflammation driven by a type 2 immune response, yet the molecular mechanisms underlying its persistence and tissue
Fanyu Yuan, Yuhan Dong, Zishuo Guo, Xiaodong Zhao, Jian Liu, Fangyuan Zhu, Shengjie Ge, Chengcheng Liu, Shuai Xu, Ming Xia   +9 more
wiley   +1 more source

Integrated morphological, molecular, histological, and antimicrobial analysis of the leather leaf slug Eleutherocaulis alte from Assiut Governorate, Egypt. [PDF]

Sci Rep
Ali SM, Mohammed TA, Salem SH, Saber HA, Abdel-Malek AR.   +4 more
europepmc   +1 more source

Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content

Food Safety and Health, EarlyView.
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao, Jiayao Wang, Yilian Huang, Na Zhang, Xiaodan Shi, Zongcai Tu, Zuohua Xie, Tao Yuan, Hongmei Yin   +8 more
wiley   +1 more source

Synthetic mucus biomaterials enable localized therapeutic antibody delivery in inflammatory bowel disease. [PDF]

APL Bioeng
Yeruva T, Yang S, Kaluzienski M, Louisthelmy R, Doski S, Maisel K, Duncan GA.   +6 more
europepmc   +1 more source

ToxPoint: Mucus matters: pollution alters mucus pathophysiology

Toxicological Sciences
Kaitlyn R Rouillard, Ilona Jaspers, David B Hill   +2 more
openaire   +1 more source

<i>Akkermansia muciniphila</i> Selectively Reshapes Small Intestinal Cell Populations. [PDF]

J Histochem Cytochem
Edens-Valentine R, Engevik KA, Engevik MA, Engevik AC.   +3 more
europepmc   +1 more source

<i><b>Akkermansia muciniphila</b></i> <b>modulates intestinal mucus composition to counteract high-fat diet-induced obesity in mice</b>. [PDF]

Gut Microbes
Paone P, Petitfils C, Puel A, Latousakis D, de Vos WM, Delzenne NM, Juge N, Van Hul M, Cani PD.   +8 more
europepmc   +1 more source