Results 61 to 70 of about 136,140 (230)

Effectiveness of biologics for reducing occlusive mucus plugs in patients with severe asthma: a systematic review

Respiratory Research
Asthma is a heterogeneous disease characterized by chronic airway inflammation and reversible airflow obstruction. Particularly in severe asthma, airway mucus plugs can contribute to substantial and persistent airflow obstruction, despite inhaled ...
Helena Aegerter, Christopher E Brightling, Eleanor M Dunican, Bart N Lambrecht, Njira L Lugogo, John D Newell, Celeste Porsbjerg, Sarah Svenningsen, Deborah Clarke, Andrew W Lindsley, Lars Nordenmark, Christopher S Ambrose, Mario Castro   +12 more
doaj   +1 more source

Plasma Cell Mucositis: A 20‐Year Retrospective Review at a Tertiary Center

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Plasma cell mucositis (PCM) is a rare, chronic inflammatory condition of mucosal surfaces that is likely underdiagnosed and underreported, with limited data on its clinical characteristics, extracavitary involvement, and treatment outcomes.
Miguel A. Aristizabal‐Torres, Jessi M. Larrinaga, Katherine Bodiford, Olayemi Sokumbi, Leila Tolaymat   +4 more
wiley   +1 more source

Allergic Bronchopulmonary Mycosis Caused by Schizophyllum commune Successfully Treated With Mepolizumab

Respirology Case Reports
Allergic bronchopulmonary mycosis (ABPM) is a complication of bronchial asthma (BA) and can lead to lung damage and respiratory failure. The standard treatment for ABPM is steroid therapy.
Mitsuki Kakiuchi, Yuki Takigawa, Ken Sato, Hiromi Watanabe, Kenichiro Kudo, Akiko Sato, Keiichi Fujiwara, Takuo Shibayama   +7 more
doaj   +1 more source

Adapted Linear Binning Method to Assess Pulmonary Ventilation and Perfusion in Children Using Lung Matrix Pencil Decomposition (MP)‐MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To adapt and validate a linear binning technique, developed for hyper‐polarized 129Xe MRI, for functional lung MRI with matrix‐pencil decomposition (MP)‐MRI. Methods First, a dedicated normalization was applied to the perfusion‐weighted and the ventilation‐weighted map histograms.
Marion Curdy, Carmen Streibel, Oliver Bieri, Elisabeth Kieninger, Florian Wyler, Lukas Ebner, Grzegorz Bauman, Philipp Latzin   +7 more
wiley   +1 more source

Simulation-Driven Annotation-Free Deep Learning for Automated Detection and Segmentation of Airway Mucus Plugs on Non-Contrast CT Images

Bioengineering
Mucus plugs are airway-obstructing accumulations of inspissated secretions frequently observed in obstructive lung diseases (OLDs), including chronic obstructive pulmonary disease (COPD), severe asthma, and cystic fibrosis.
Lucy Pu, Naciye Sinem Gezer, Tong Yu, Zehavit Kirshenboim, Emrah Duman, Rajeev Dhupar, Xin Meng   +6 more
doaj   +1 more source

Effects of Surface Tension and Yield Stress on Mucus Plug Rupture: a Numerical Study

, 2019
International audienceWe study the effects of surface tension and yield stress on mucus plug rupture. A three-dimensional simplified configuration is employed to simulate mucus plug rupture in a collapsed lung airway of the 10 th generation. The Herschel-
Romano, Francesco, Grotberg, James B., Hu, Yingying   +2 more
core   +1 more source

Gastric Output of Pancreatic Secretory Trypsin-Inhibitor Is Increased by Misoprostol [PDF]

, 1991
Pancreatic secretory trypsin inhibitor (PSTI) is a potent protease inhibitor that also has growth promoting activity. It has recently been identified in the foveolar cells of the stomach, which secrete mucus.
Batten, J J, Calam, J, Freeman, T C, Vesey, D A, Batten, JJ, Baron, J H, Baron, JH, Playford, RJ, Fenn, GC, Freeman, TC, Beardshall, K, Playford, R J, Beardsall, K, Fenn, G C, Vesey, DA   +14 more
core   +1 more source

Emergencies in Amyotrophic Lateral Sclerosis

Muscle &Nerve, EarlyView.
ABSTRACT Emergencies are frequent in people living with amyotrophic lateral sclerosis (pALS), especially as the disease progresses, and can necessitate urgent evaluation and intervention. Progressive weakness in ALS inevitably increases fall risk, making discussion of fall prevention strategies integral to caring for pALS.
S. Pinar Uysal, Katherine A. Dudley, Stacey Sullivan, Kate T. Brizzi, Katherine M. Burke, Sydney Hall, Kiersten Pease, Joshua N. Goldstein, James D. Berry, Doreen T. Ho   +9 more
wiley   +1 more source

Maternal Lead Exposure Induces Glandular Alterations in the Salivary Glands of Rat Male Offspring

Environmental Toxicology, EarlyView.
ABSTRACT Lead (Pb) is a widely distributed environmental pollutant that is highly noxious due to its toxicokinetic characteristics. Pb exposure can damage vital organ systems, including the central nervous and stomatognathic systems. As salivary glands play an important role in oral homeostasis, this study aimed to investigate the effects of maternal ...
Rayssa Maitê Farias Nazário, Deiweson Souza‐Monteiro, Walessa Alana Bragança Aragão, Luciana Eiró‐Quirino, Leonardo Oliveira Bittencourt, Raquel Fernanda Gerlach, Antônio Hernandes Chaves‐Neto, Michael Aschner, Rafael Rodrigues Lima   +8 more
wiley   +1 more source

High Versus Low Transvaginal Cerclage and Pregnancy Outcomes: A Secondary Analysis of the C‐STICH Trial

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To compare pregnancy outcomes following high versus low vaginal cerclage in women at high risk of preterm birth. Design Secondary analysis of a multi‐centre randomised control trial. Setting Obstetric units across the UK. Sample Women participating in the C‐STICH trial who received a transvaginal cerclage. Methods Cerclage height was
Laura van der Krogt, Nicole Pilarski, Victoria Hodgetts Morton, Alexandra Emms, Philip Toozs‐Hobson, Lee Middleton, Andrew Shennan, Catherine A. Moakes   +7 more
wiley   +1 more source