Results 1 to 10 of about 53,249 (182)

Mucus Plugs Persist in Asthma, and Changes in Mucus Plugs Associate with Changes in Airflow over Time [PDF]

American Journal of Respiratory and Critical Care Medicine, 2022
Abstract Rationale Cross-sectional analysis of mucus plugs in computed tomography (CT) lung scans in the Severe Asthma Research Program (SARP)-3 showed a high mucus plug phenotype. Objectives To determine if mucus ...
John Fahy, Sb Fain, Brett Elicker
exaly   +6 more sources

Airway mucus plugs in COPD clinical phenotypes and prognosis across stable and exacerbation states

Scientific Reports
The study aimed to observe the airway mucus plugs in patients with stable chronic obstructive pulmonary disease (COPD) versus those with acute exacerbation of COPD(AECOPD), and examine the clinical characteristics and prognosis in stable COPD and AECOPD ...
Zeng Yuqin
exaly   +3 more sources

Differential role of mucus plugs in asthma: Effects of smoking and association with airway inflammation

Allergology International, 2023
Background: The physiological importance of mucus plugs in computed tomography (CT) imaging is being increasingly recognized. However, whether airway inflammation and smoking affect the association between mucus plugs and clinical–physiological outcomes ...
Isao Yokota, Satoshi Konno, Masaru Suzuki   +2 more
exaly   +4 more sources

Effectiveness of biologics for reducing occlusive mucus plugs in patients with severe asthma: a systematic review

Respiratory Research
Asthma is a heterogeneous disease characterized by chronic airway inflammation and reversible airflow obstruction. Particularly in severe asthma, airway mucus plugs can contribute to substantial and persistent airflow obstruction, despite inhaled ...
Mario Castro, Helena Catharine Aegerter, Chris Brightling   +2 more
exaly   +3 more sources

Successful treatment with dupilumab for mucus plugs in severe asthma

Respirology Case Reports, 2023
A 29‐year‐old man presented to our hospital with severe eosinophilic asthma. He needed a short OCS burst for exacerbation of asthma once every 1 or 2 months, although he used a high dose of inhaled corticosteroids and a long‐acting beta‐2 agonists. Chest
Takuro Sakagami, Moriyasu Anai
exaly   +4 more sources

Mucus plugs in the airways of asthmatic subjects and smoking status

Respiratory Research
Background Mucus plugs have been described in the airways of asthmatic subjects, particularly those with associated with type 2 inflammation and sputum eosinophilia.
Camille Audousset, Sana Swaleh, Ron Olivenstein, Motahareh Vameghestahbanati, Miranda Kirby, Alexandre Semionov, Benjamin M. Smith, James G. Martin   +7 more
doaj   +4 more sources

Mucus plug and lung cancer incidence in patients with COPD

Scientific Reports
Airway mucus plugs are frequently observed on chest computed tomography (CT) scans in patients with chronic obstructive pulmonary disease (COPD). However, the association between the presence of mucus plugs and the risk of lung cancer in COPD patients ...
So Jeong Kim, Heemoon Park, Hyo Jin Lee, Jung-Kyu Lee, Eun Young Heo, Kwang Nam Jin, Deog Kyeom Kim, Hyun Woo Lee   +7 more
doaj   +4 more sources

Compilation of Harm: Tobacco, Chronic Obstructive Pulmonary Disease, and Mucus Plugs. Systematic Review of the Literature and Meta-Analysis

Open Respiratory Archives
Introduction: In COPD patients, mucus plugs are associated with lower lung function, worse quality of life, higher all-cause mortality, and a higher rate of exacerbations.
Daniel Lopez-Padilla, José Ignacio de Granda-Orive, Rafael Aleixandre-Benavent   +2 more
exaly   +4 more sources

Clinical characteristics and factors associated with mucus plugs under bronchoscopy in children hospitalized for acute asthma attack

Frontiers in Pediatrics
ObjectiveTo describe clinical characteristics of hospitalized children with acute asthma attacks complicated with mucus plugs and to investigate the factors associated with mucus plugs in asthma children.MethodsThis retrospective study analyzed ...
Anxia Jiao
exaly   +3 more sources

Possible Biological Heterogeneity of Airway Mucus Plugs in a Patient with Asthma

Journal of Asthma and Allergy
Hiroki Tashiro, Mizuki Nanri, Yuki Kuwahara, Yuki Kurihara, Shinya Kimura, Koichiro Takahashi Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Saga, Saga Prefecture ...
Hiroki Tashiro, Koichiro Takahashi, Shinya Kimura   +2 more
exaly   +2 more sources