Results 21 to 30 of about 53,249 (182)

Supplementary Material for: Effect of benralizumab on mucus plugs in severe eosinophilic asthma

open access: yes, 2023
Introduction: Mucus plugs are associated with airway obstruction in severe asthma and are involved in the formation of activated eosinophils. Benralizumab, an anti-interleukin-5 receptor antibody, markedly reduces not only peripheral blood eosinophils ...
Sakai N. (4124452)   +11 more
core   +1 more source

Functional characterization of a mucus-specific LPXTG surface adhesin from probiotic Lactobacillus rhamnosus GG [PDF]

open access: yes, 2011
In spite of the wealth of clinical evidence supporting the health benefits of Lactobacillus rhamnosus GG in humans, there is still a lack of understanding of the molecular mechanisms behind its probiosis.
Vos, W.M., de   +17 more
core   +1 more source

Novel imaging phenotypes of naïve asthma patients with distinctive clinical characteristics and T2 inflammation traits

open access: yesTherapeutic Advances in Chronic Disease, 2022
Objective: This study aims to describe the imaging features of naïve asthma patients, defined as not receiving corticosteroids or other asthma medications for at least 1 month, and their association with therapeutic response, and to discover novel ...
Zhenyu Yang   +12 more
doaj   +1 more source

Case Report: Eosinophilic Bronchiolitis With Eosinophil ETosis in Mucus Plugs Successfully Treated With Benralizumab

open access: yesFrontiers in Pharmacology, 2022
Eosinophilic bronchiolitis is a rare allergic disorder caused by eosinophilic inflammation in the bronchioles of the lungs. An effective treatment strategy is needed in cases resistant to steroids.
Hisashi Sasaki   +6 more
doaj   +1 more source

The biochemical characterisation of respiratory mucus & mucins in normal, asthma & COPD [PDF]

open access: yes, 2009
Includes abstract.Includes bibliographical references (leaves 78-87).Airway mucus hyper-secretion is the main cause of mortality and morbidity in respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD) and is the leading ...
Trimmel, Astrid Joan
core   +1 more source

Clinical periodontal diagnosis

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi   +5 more
wiley   +1 more source

A case of allergic bronchopulmonary aspergillosis with marked peripheral blood eosinophilia successfully treated with benralizumab

open access: yesRespiratory Medicine Case Reports, 2021
We herein report a case of allergic bronchopulmonary aspergillosis (ABPA) with marked eosinophilia and high attenuation mucus (HAM) on chest computed tomography (CT), which demonstrated a rapid and remarkable improvement with benralizumab treatment. A 67-
Kazuya Tsubouchi   +5 more
doaj   +1 more source

Location of Clot in Patients with COPD Experiencing Pulmonary

open access: yesThoracic Research and Practice
Objective: The study aimed to investigate the impact of mucus plugs on the localization of clots in pulmonary embolisms among chronic obstructive pulmonary disease (COPD) patients.
Neda Akhoundi   +3 more
doaj   +1 more source

Comparison of hyperpolarized 3He-MRI, CT based parametric response mapping, and mucus scores in asthmatics

open access: yesFrontiers in Physiology, 2023
Purpose: The purpose of this study was to anatomically correlate ventilation defects with regions of air trapping by whole lung, lung lobe, and airway segment in the context of airway mucus plugging in asthma.Methods: A total of 34 asthmatics [13M:21F ...
Katherine J. Carey   +14 more
doaj   +1 more source

Mucus-Inspired Tribology, a Sticky Yet Flowing Hydrogel

open access: yes
The mucus blanket can trap foreign particles before they enter the lungs, while at the same time, it flows up to remove these particles. This manifests the dual nature of mucus: sticky, on one hand, and fluid, on the other.
Prabir K. Patra (1920082)   +9 more
core   +7 more sources

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