Diagnostics, 2023 Sebaceous neoplasms describe a group of tumors with sebaceous differentiation commonly seen in lesions located primarily in the face and neck. The majority of these lesions are benign, while malignant neoplasms with sebaceous differentiation are uncommon.
Ilias Papadimitriou +5 more
doaj +1 more source
Case for diagnosis. Verrucous plaque on the pubic region, [PDF]
Anais Brasileiros de Dermatologia, 2021 Muir-Torre syndrome is a rare, autosomal dominant genodermatosis, characterized by sebaceous neoplasms and visceral carcinomas. The authors describe the case of a patient who, 16 years after the diagnosis of colon carcinoma, presented a verrucous plaque ...
Diego Henrique Morais Silva +3 more
doaj +1 more source
Multiple sebaceous tumors in a 58‐year‐old man with colorectal cancer
Clinical Case Reports, 2022 The Muir‐Torre Syndrome is a rare genodermatosis, defined by the occurrence of sebaceous neoplasia and internal malignancies and caused by mutations in the mismatch repair gene.
Mohamed Ben Rejeb +6 more
doaj +1 more source
Muir-Torre syndrome - Treatment with isotretinoin and interferon alpha-2a can prevent tumour development [PDF]
, 2000 Muir-Torre syndrome is a genodermatosis in which multiple internal malignancies are associated with cutaneous sebaceous tumours and kerato-acanthomas. A 57-year-old man presented with multiple sebaceous tumours, kerato-acanthomas, verrucous carcinoma of ...
Burgdorf, Walter H. C. +3 more
core +1 more source
Role of microsatellite instability, immunohistochemistry and Mismatch Repair germline aberrations in immunosuppressed transplant patients: a phenocopy dilemma in Muir-Torre Syndrome. [PDF]
, 2016 Sebaceous tumours and keratoacanthomas are uncommon neoplasms that constitute important clinical criteria for Muir-Torre Syndrome (MTS) diagnosis. In MTS patients, the increased risk of developing synchronous or metachronous visceral malignancies is ...
Manfredini, Marco +3 more
core +1 more source
FDG-PET-positive lower-extremity sebaceous-gland carcinoma in a patient with Muir-Torre syndrome
Radiology Case Reports, 2015 Sebaceous-gland carcinoma can occur alone or as one of the defining features of the Muir-Torre syndrome. Cases occurring below the head and neck are extremely rare.
Bina Kviatkovsky, MSc +7 more
doaj +1 more source
Identification of human papillomavirus DNA in cutaneous lesions of Cowden syndrome [PDF]
, 2003 Background: Cowden syndrome (CS) or multiple hamartoma syndrome is a cancer-associated genodermatosis inherited in an autosomal dominant pattern. One of the diagnostic criteria is facial papules which are felt to be trichilemmomas, benign hair follicle ...
Burgdorf, Walter H. C. +4 more
core +1 more source
Journal of Surgical Oncology, Volume 128, Issue 8, Page 1380-1384, December 15, 2023., 2023 Abstract Background Muir–Torre syndrome (MTS) is a rare genetic disorder that is caused by mismatch repair (MMR) protein mutations. MTS increases the risk of developing skin and gastrointestinal tumors such as sebaceous adenomas (SAs), sebaceous carcinomas, colorectal cancer, endometrial cancer, and ovarian cancer. The risk of developing these types of
Nada Shaker +5 more
wiley +1 more source
Microsatellite instability, immunohistochemistry and germline mismatch repair gene mutations for the diagnosis of Muir-Torre syndrome in immunosuppressed patients [PDF]
, 2016 Although rare sebaceous tumors and keratoacanthomas are clinical criteria for Muir-Torre syndrome (MTS), they can also be found in the context of immunosuppression.
Gorelli, Greta +4 more
core +1 more source
Muir-Torre Syndrome with Novel Mutation in the MSH2 Gene [PDF]
, 2023 Muir-Torre syndrome (MST) is a rare autosomal dominant subtype of hereditary non-polyposis colorectal carcinoma. The diagnosis is established based on the coexistence of sebaceous gland tumors and visceral organ malignancies. Mutations in the mismatch
Agirgol, Senay +3 more
core +1 more source