Muir-Torre Syndrome: The Importance of a Detailed Family History [PDF]
Case Reports in Ophthalmology, 2019 Muir-Torre syndrome, a variant of Lynch syndrome or hereditary nonpolyposis colorectal cancer, is an autosomal dominant disease characterized by skin neoplasms (sebaceous or keratoacanthomas) and visceral malignancies.
Christopher K.H. Burris +7 more
doaj +4 more sources
Clinical and Molecular Features of Skin Malignancies in Muir-Torre Syndrome [PDF]
Genes, 2021 Background: We investigated the mutational landscape of skin tumors in patients with Muir-Torre Syndrome (MTS) a hereditary autosomal dominant mismatch repair disorder of increased cancer susceptibility, and examined mutations other than in the DNA ...
Sandra N Freiberger +2 more
exaly +8 more sources
Maintenance Intravenous Immunoglobulin Treatment for Multiple Sclerosis Coexisting with Ehlers-Danlos Syndrome and Muir-Torre Syndrome: A Case Study [PDF]
Neurology and Therapy, 2020 The therapeutic options for disease modification in relapsing-remitting multiple sclerosis (RRMS) have expanded remarkably in the last 15 years. Although intravenous immunoglobulins (IVIg) have shown some therapeutic effects in multiple sclerosis ...
Srishti Gupta +2 more
doaj +3 more sources
FDG-PET-positive lower-extremity sebaceous-gland carcinoma in a patient with Muir-Torre syndrome [PDF]
Radiology Case Reports, 2015 Sebaceous-gland carcinoma can occur alone or as one of the defining features of the Muir-Torre syndrome. Cases occurring below the head and neck are extremely rare.
Bina Kviatkovsky, MSc +7 more
doaj +3 more sources
Papillary Renal Cell Carcinoma in Lynch/Muir-Torre Syndrome with Germline Pathogenic Variant in MSH6 and Molecular Analysis [PDF]
Journal of Kidney Cancer and VHL, 2021 Lynch syndrome (LS) is an autosomal dominant inherited disorder due to pathogenic variations in the mismatch repair genes, which predisposes to malignancies, most commonly colon and endometrial carcinoma.
Yu Yang +3 more
doaj +2 more sources
Urothelial Carcinoma Recurrence in an Ileal Neobladder Nine Years after Primary Surgery with Muir-Torre Syndrome [PDF]
Case Reports in Urology, 2016 We report a patient who presented with a urothelial carcinoma recurrence developed nine years after radical cystoprostatectomy, related to Muir-Torre syndrome.
Floryn Cherbanyk +5 more
doaj +2 more sources
Hereditary Cancer in Clinical Practice, 2017 Background The tumor spectrum in the Lynch syndrome is well defined, comprising an increased risk of developing colonic and extracolonic malignancies. Muir-Torre syndrome is a variant with a higher risk of skin disease.
Caroline Kientz +9 more
doaj +2 more sources
Russian Journal of Clinical Dermatology and Venereology, 2023 The clinical case of Muir-Torre syndrome in a patient with multifocal synchronous basal cell skin cancer with sebaceous differentiation and endometrial cancer in a medical history, including clinical manifestations and dermatoscopic pattern features of sebaceous adenoma, epithelioma with sebaceous glandular differentiation and sebaceous glandular skin ...
Gay JT, Troxell T, Gross GP.
europepmc +2 more sources
Myxofibrosarcoma harboring an MLH1 pathogenic germline variant associated with Muir-Torre syndrome: a case report [PDF]
Hereditary Cancer in Clinical Practice, 2021 Background Muir–Torre syndrome (MTS), which accounts for a small subset (1–3 %) of Lynch syndrome (LS), is an autosomal dominant genetic disorder characterized by sebaceous gland or keratoacanthoma associated with visceral malignancies.
Makoto Nakagawa +13 more
doaj +2 more sources
Muir-Torre Syndrome: case report and molecular characterization
São Paulo Medical JournalCONTEXT: Muir-Torre syndrome is a rare autosomal dominant genodermatosis caused by mutations in the mismatch repair genes. It is characterized by the presence of sebaceous skin tumors and internal malignancies, affecting mainly the colon, rectum and ...
Carolina Alejandra Rios +4 more
doaj +2 more sources