Results 71 to 80 of about 836,282 (224)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Hybrid Metaheuristics for Multi-Objective Optimization

open access: yesJournal of Algorithms & Computational Technology, 2015
Over the last two decades, interest on hybrid metaheuristics has risen considerably in the field of multi-objective optimization (MOP). The best results found for many real-life or academic multi-objective optimization problems are obtained by hybrid ...
E-G. Talbi
doaj   +1 more source

Multi-Objective Framework for Dynamic Optimization of OFDMA Cellular Systems

open access: yes, 2016
Green cellular networking has become an important research area in recent years due to environmental and economical concerns. Switching off under-utilized BSs during off-peak traffic load conditions is a promising approach to reduce energy consumption in
Chandhar, Prabhu, Das, Suvra Sekhar
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Multi-objective optimization of Resin Infusion

open access: yesAdvanced Manufacturing: Polymer & Composites Science, 2019
The present paper addresses the multi-objective optimization of the filling stage of the Resin Infusion manufacturing process. The optimization focuses on the selection of an optimal temperature profile which addresses the tradeoff between filling time ...
G. Struzziero, A. A. Skordos
doaj   +1 more source

Multi-Objective Optimization for Power Efficient Full-Duplex Wireless Communication Systems

open access: yes, 2015
In this paper, we investigate power efficient resource allocation algorithm design for multiuser wireless communication systems employing a full-duplex (FD) radio base station for serving multiple half-duplex (HD) downlink and uplink users simultaneously.
Ng, Derrick Wing Kwan   +2 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Research on Multi-Objective Optimization of Smart Grid Based on Particle Swarm Optimization

open access: yesElectrica, 2023
Fei Long   +5 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

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