Results 31 to 40 of about 17,273 (262)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Assessment of the Governance System Regarding Adoption of Energy Efficient Appliances by Households in Nigeria

open access: yesEnergies, 2017
The adoption of energy efficient electrical appliances by households has a great potential to reduce electricity consumption in Nigeria. A well-formulated and implemented policy (mix) to spur adoption is said to be required to drive this process.
James A. Gana, Thomas Hoppe
doaj   +1 more source

Collaborative Decision-Making Method for Multi-UAV Based on Multiagent Reinforcement Learning

open access: yesIEEE Access, 2022
The collaborative mission capability of multi-UAV has received more and more attention in recent years as the research on multi-UAV theories and applications has intensified.
Shaowei Li   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Operational Design Domain Requirements for Improved Performance of Lane Assistance Systems: A Field Test Study in The Netherlands

open access: yesIEEE Open Journal of Intelligent Transportation Systems, 2020
There is a pressing need for road authorities to take a proactive role in the deployment of automated vehicles on the existing road network. This requires a comprehensive understanding of the driving environment characteristics that affect the ...
Nagarjun Reddy   +4 more
doaj   +1 more source

A Relational Approach to Leadership for Multi-Actor Governance [PDF]

open access: yesAdministrative Sciences, 2019
Multi-actor governance, in which a broad mix of actors collaborates to deal with complex societal problems, requires a leadership approach that can take into account the dynamic interdependencies between the involved actors. A relational approach to leadership, focusing on processes and practices, is more adequate for that purpose than approaches ...
Craps, M.   +5 more
openaire   +3 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Private investments in climate change adaptation are increasing in Europe, although sectoral differences remain

open access: yesCommunications Earth & Environment
Climate-induced hazards are becoming more frequent and severe, causing escalating economic losses worldwide. Consequently, climate change adaptation is increasingly necessary to protect people, nature and the economy.
Ignasi Cortés Arbués   +4 more
doaj   +1 more source

Harvesting living labs outcomes through learning pathways

open access: yesCurrent Research in Environmental Sustainability
Living labs have emerged as a long-term, collaborative approach to addressing complex societal challenges, such as sustainable land and water management and climate change adaption.
Astha Bhatta   +2 more
doaj   +1 more source

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