Results 41 to 50 of about 191,080 (266)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Nondestructive intervention to multi-agent systems through an intelligent agent. [PDF]

open access: yesPLoS ONE, 2013
For a given multi-agent system where the local interaction rule of the existing agents can not be re-designed, one way to intervene the collective behavior of the system is to add one or a few special agents into the group which are still treated as ...
Jing Han, Lin Wang
doaj   +1 more source

Multi-Agent-Based Controller for Microgrids: An Overview and Case Study

open access: yesEnergies, 2023
A microgrid can be defined as a grid of interconnected distributed energy resources, loads and energy storage systems. In microgrid systems containing renewable energy resources, the coordinated operation of distributed generation units is important to ...
Necmi Altin   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Rationality in Multi-Agent Systems [PDF]

open access: yesThe Knowledge Engineering Review, 1998
This report is the result of a panel discussion at the Second UK Workshop on Foundations of Multi-Agent Systems (FOMAS'97). All members of the panel are authors, listed alphabetically.
Ken Binmore   +3 more
openaire   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Observer-Based PID Control Protocol of Positive Multi-Agent Systems

open access: yesMathematics, 2023
This paper proposes the observer-based proportional-integral-derivative control of positive multi-agent systems. First, a positive observer is constructed for the considered multi-agent systems in terms of a matrix decomposition approach.
Xiaogang Yang   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Niching In Evolutionary Multi-Agent Systems

open access: yesComputer Science, 2013
Niching is a group of techniques used in evolutionary algorithms, useful inseveral types of problems, including multimodal or nonstationary optimiza-tion. This paper investigates the applicability of these methods to evolutionarymulti-agent systems (EMAS)
Daniel Krzywicki
doaj   +1 more source

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