Results 41 to 50 of about 437,042 (308)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Optimal AGC with redox flow batteries in multi-area restructured power systems

Engineering Science and Technology, an International Journal, 2016
This paper attempts to investigate the effect of Redox flow batteries (RFB) in Automatic Generation Control (AGC) of multi-area restructured power systems. Initially, a two-area restructured thermal power system is investigated. For the analysis, optimal
Yogendra Arya, Narendra Kumar
doaj   +1 more source

Power system modeling for multi-area regulating market simulation

, 2005
In a power system with many fast and/or large changes in the generation or the consumption, for example in a system with large amounts of wind power, the frequency control is more complicated to handle efficiently.
Elin Lindgren, Lindgren, Elin,, Lennart Soder, Söder, Lennart,   +3 more
core   +1 more source

Multi-Area Optimal Power Flow Problem Through Parallel Processing

, 2023
Funding Information: This paper was supported in part by the São Paulo Research Foundation (FAPESP) er rants 2019/0u1–G5 1n8d4 and2015/21972–6,npartytheBrazilianNatbiolCoucil nna for cientific nd TechSlogical Daevelopent (CNPq) under nmo Grant 304726 ...
Mantovani, Jose Roberto Sanches, Pourakbari-Kasmaei, Mahdi, Do Carmo Yamaguti, Lucas, Mantovani, Jose Roberto Sanches [UNESP], Home-Ortiz, Juan M., Home-Ortiz, Juan M. [UNESP], Do Carmo Yamaguti, Lucas [UNESP]   +6 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

A multi‐area design of under frequency load shedding schemes considering energy storage system

IET Generation, Transmission & Distribution, 2023
This paper presents a comprehensive under frequency load shedding (UFLS) model that can be implemented in a multi‐area power system with real network characteristics.
Ahmadreza Alavi‐Koosha, Turaj Amraee, Salar Saberi Oskouee   +2 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Economic Load Dispatch of A Multi‐Area Power System Using Multi‐Agent Distributed Optimization Based on Genetic Algorithm

Energy Science & Engineering
This study presents a new methodology for distributed multi‐agent optimization utilizing a genetic algorithm to address Multi‐Area Economic Dispatch Problem (MAEDP) in a power system.
Seyed Yaser Fakhrmousavi, Seyed Babak Mazafari, Shahram Javadi, Mahmood Hosseini Aliabadi   +3 more
doaj   +1 more source

Load Frequency Control Using Hybrid Intelligent Optimization Technique for Multi-Source Power Systems

Energies, 2021
The automatic load frequency control for multi-area power systems has been a challenging task for power system engineers. The complexity of this task further increases with the incorporation of multiple sources of power generation. For multi-source power
Deepak Kumar Gupta, Amitkumar V. Jha, Bhargav Appasani, Avireni Srinivasulu, Nicu Bizon, Phatiphat Thounthong   +5 more
doaj   +1 more source